DK1599478T3 - Dihydropteridinones, their method of preparation and their use as a drug - Google Patents

Dihydropteridinones, their method of preparation and their use as a drug

Info

Publication number
DK1599478T3
DK1599478T3 DK03816028T DK03816028T DK1599478T3 DK 1599478 T3 DK1599478 T3 DK 1599478T3 DK 03816028 T DK03816028 T DK 03816028T DK 03816028 T DK03816028 T DK 03816028T DK 1599478 T3 DK1599478 T3 DK 1599478T3
Authority
DK
Denmark
Prior art keywords
dihydropteridinones
drug
preparation
isomers
rests
Prior art date
Application number
DK03816028T
Other languages
Danish (da)
Inventor
Steffen Breitfelder
Christian Eickmeier
Martin Steegmaier
Gisela Schnapp
Anke Baum
Jens Juergen Quant
Flavio Solca
Florian Colbatzky
Matthias Hoffmann
Matthias Grauert
Trixi Brandl
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Application granted granted Critical
Publication of DK1599478T3 publication Critical patent/DK1599478T3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The invention relates to novel dihydropteridinones of general formula (I), wherein rests L, R<1>-R<5 >have the significance indicated in claims and a specification, in the isomers thereof, in a method for producing and using said dihydropteridinones in the form of drugs.
DK03816028T 2003-02-26 2003-02-26 Dihydropteridinones, their method of preparation and their use as a drug DK1599478T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2003/001935 WO2004076454A1 (en) 2003-02-26 2003-02-26 Dihydropteridinones, method for the production and use thereof in the form of drugs

Publications (1)

Publication Number Publication Date
DK1599478T3 true DK1599478T3 (en) 2007-09-17

Family

ID=32921552

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03816028T DK1599478T3 (en) 2003-02-26 2003-02-26 Dihydropteridinones, their method of preparation and their use as a drug

Country Status (27)

Country Link
EP (1) EP1599478B1 (en)
JP (1) JP3876265B2 (en)
KR (1) KR100983462B1 (en)
CN (2) CN101200457A (en)
AT (1) ATE361924T1 (en)
AU (1) AU2003215591B2 (en)
BR (1) BR0318145A (en)
CA (1) CA2517020C (en)
CY (1) CY1106752T1 (en)
DE (1) DE50307267D1 (en)
DK (1) DK1599478T3 (en)
EA (1) EA008778B1 (en)
ES (1) ES2287583T3 (en)
HK (1) HK1089444A1 (en)
HR (1) HRP20050735B1 (en)
IL (1) IL170419A (en)
ME (1) ME00376B (en)
MX (1) MXPA05009068A (en)
NO (1) NO332538B1 (en)
NZ (1) NZ542498A (en)
PL (1) PL226417B1 (en)
PT (1) PT1599478E (en)
RS (1) RS52386B (en)
SI (1) SI1599478T1 (en)
TW (1) TWI313600B (en)
UA (1) UA80743C2 (en)
WO (1) WO2004076454A1 (en)

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Also Published As

Publication number Publication date
SI1599478T1 (en) 2007-10-31
UA80743C2 (en) 2007-10-25
CN101200457A (en) 2008-06-18
ME00376B (en) 2011-10-10
TWI313600B (en) 2009-08-21
IL170419A (en) 2013-11-28
NZ542498A (en) 2009-01-31
WO2004076454A1 (en) 2004-09-10
RS52386B (en) 2013-02-28
HRP20050735A2 (en) 2006-07-31
ATE361924T1 (en) 2007-06-15
NO20054414L (en) 2005-09-23
KR20050113198A (en) 2005-12-01
CA2517020A1 (en) 2004-09-10
EP1599478B1 (en) 2007-05-09
CN100537570C (en) 2009-09-09
HRP20050735B1 (en) 2013-08-31
JP2006514667A (en) 2006-05-11
EA200501222A1 (en) 2006-04-28
PL378168A1 (en) 2006-03-06
PL226417B1 (en) 2017-07-31
JP3876265B2 (en) 2007-01-31
MEP58808A (en) 2011-05-10
MXPA05009068A (en) 2005-10-19
BR0318145A (en) 2006-02-21
KR100983462B1 (en) 2010-09-27
EP1599478A1 (en) 2005-11-30
EA008778B1 (en) 2007-08-31
CA2517020C (en) 2012-06-26
CN1745081A (en) 2006-03-08
PT1599478E (en) 2007-05-31
DE50307267D1 (en) 2007-06-21
AU2003215591A1 (en) 2004-09-17
AU2003215591B2 (en) 2010-06-17
CY1106752T1 (en) 2012-05-23
NO332538B1 (en) 2012-10-15
ES2287583T3 (en) 2007-12-16
HK1089444A1 (en) 2006-12-01
RS20050648A (en) 2007-11-15
TW200417369A (en) 2004-09-16

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