DK156003C - METHOD OF ANALOGUE FOR THE PREPARATION OF (2,4,6-TRIMETHOXYPHENYL) - (3-HEXAMETHYLENIMINOPROPYL) -KETON OR ACID ADDITION SALTS OR QUATERNARY AMMONIUM SALTS. - Google Patents

METHOD OF ANALOGUE FOR THE PREPARATION OF (2,4,6-TRIMETHOXYPHENYL) - (3-HEXAMETHYLENIMINOPROPYL) -KETON OR ACID ADDITION SALTS OR QUATERNARY AMMONIUM SALTS.

Info

Publication number
DK156003C
DK156003C DK489283A DK489283A DK156003C DK 156003 C DK156003 C DK 156003C DK 489283 A DK489283 A DK 489283A DK 489283 A DK489283 A DK 489283A DK 156003 C DK156003 C DK 156003C
Authority
DK
Denmark
Prior art keywords
trimethoxyphenyl
addition salts
hexamethyleniminopropyl
keton
analogue
Prior art date
Application number
DK489283A
Other languages
Danish (da)
Other versions
DK489283D0 (en
DK156003B (en
DK489283A (en
Inventor
Louis Lafon
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of DK489283D0 publication Critical patent/DK489283D0/en
Publication of DK489283A publication Critical patent/DK489283A/en
Publication of DK156003B publication Critical patent/DK156003B/en
Application granted granted Critical
Publication of DK156003C publication Critical patent/DK156003C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Claims for the contracting state AT Use of the (2,4,6-trimethoxyphenyl)-3-(hexamethyleneiminopropyl)-ketone having the following structural formula see diagramm : EP0110748,P6,F1 and its non toxic addition salts, for the manufacture of a medicine. 1. Claims for the contracting states BE, CH, DE, FR, GB, IT, LI, LU, NL, SE, The (2,4,6-trimethoxyphenyl)-(3-hexamethyleneiminopropyl)-ketone having the following structural formula see diagramm : EP0110748,P7,F1 and its addition salts.
DK489283A 1982-10-26 1983-10-25 METHOD OF ANALOGUE FOR THE PREPARATION OF (2,4,6-TRIMETHOXYPHENYL) - (3-HEXAMETHYLENIMINOPROPYL) -KETON OR ACID ADDITION SALTS OR QUATERNARY AMMONIUM SALTS. DK156003C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8217937 1982-10-26
FR8217937A FR2534916B1 (en) 1982-10-26 1982-10-26 NOVEL PHENYL- (3-AMINOPROPYL) -CETONE DERIVATIVES, USE IN THERAPEUTICS AND PREPARATION METHOD

Publications (4)

Publication Number Publication Date
DK489283D0 DK489283D0 (en) 1983-10-25
DK489283A DK489283A (en) 1984-04-27
DK156003B DK156003B (en) 1989-06-12
DK156003C true DK156003C (en) 1989-11-13

Family

ID=9278617

Family Applications (1)

Application Number Title Priority Date Filing Date
DK489283A DK156003C (en) 1982-10-26 1983-10-25 METHOD OF ANALOGUE FOR THE PREPARATION OF (2,4,6-TRIMETHOXYPHENYL) - (3-HEXAMETHYLENIMINOPROPYL) -KETON OR ACID ADDITION SALTS OR QUATERNARY AMMONIUM SALTS.

Country Status (11)

Country Link
EP (1) EP0110748B1 (en)
JP (1) JPS5995283A (en)
AT (1) ATE26712T1 (en)
AU (1) AU556589B2 (en)
CA (1) CA1212944A (en)
DE (1) DE3371077D1 (en)
DK (1) DK156003C (en)
ES (1) ES8406069A1 (en)
FR (1) FR2534916B1 (en)
GR (1) GR79617B (en)
IE (1) IE56129B1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2584715B1 (en) * 1985-07-10 1987-10-09 Lafon Labor PHENYL- (3-HEXAMETHYLENEIMINOPROPYL) -CETONE, PROCESS FOR PREPARATION AND THERAPEUTIC USE
TW248554B (en) * 1993-05-26 1995-06-01 Syntex Inc

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR6945M (en) * 1967-12-22 1969-05-12
FR2092133B1 (en) * 1970-05-06 1974-03-22 Orsymonde
FR2101045A1 (en) * 1970-08-12 1972-03-31 Penciolelli Madeleine Omega-dialkylamino-1-(2,4,6-trialkoxy phenyl) alkan-1-ones - with vasodilator and spasmolytic activity
FR2134218A1 (en) * 1971-04-27 1972-12-08 Penciolelli Madeleine Phloroglucinol aminoketones - vasodilators and antispasmodics

Also Published As

Publication number Publication date
ES526736A0 (en) 1984-07-01
DK489283D0 (en) 1983-10-25
GR79617B (en) 1984-10-31
EP0110748B1 (en) 1987-04-22
CA1212944A (en) 1986-10-21
ATE26712T1 (en) 1987-05-15
AU2056883A (en) 1984-05-03
EP0110748A1 (en) 1984-06-13
FR2534916B1 (en) 1985-11-22
DE3371077D1 (en) 1987-05-27
AU556589B2 (en) 1986-11-13
DK156003B (en) 1989-06-12
IE832488L (en) 1984-04-26
FR2534916A1 (en) 1984-04-27
JPS5995283A (en) 1984-06-01
DK489283A (en) 1984-04-27
ES8406069A1 (en) 1984-07-01
IE56129B1 (en) 1991-04-24

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