DK151813C - METHOD OF ANALOGUE FOR THE PREPARATION OF ESTERS OF N-ACETYL-MURAMYL-L-ALANYL-D-GLUTAMIC ACID AND OF N-ACETYL-MURAMYL-L-ALANYL-D-ISOGLUTAMINE - Google Patents

METHOD OF ANALOGUE FOR THE PREPARATION OF ESTERS OF N-ACETYL-MURAMYL-L-ALANYL-D-GLUTAMIC ACID AND OF N-ACETYL-MURAMYL-L-ALANYL-D-ISOGLUTAMINE

Info

Publication number
DK151813C
DK151813C DK105477A DK105477A DK151813C DK 151813 C DK151813 C DK 151813C DK 105477 A DK105477 A DK 105477A DK 105477 A DK105477 A DK 105477A DK 151813 C DK151813 C DK 151813C
Authority
DK
Denmark
Prior art keywords
muramyl
alanyl
acetyl
isoglutamine
analogue
Prior art date
Application number
DK105477A
Other languages
Danish (da)
Other versions
DK105477A (en
DK151813B (en
Inventor
Francoise Audibert
Louis Chedid
Pierre Lefrancier
Jean Choay
Edgar Lederer
Original Assignee
Anvar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7606820A external-priority patent/FR2343483A1/en
Priority claimed from FR7702646A external-priority patent/FR2369292A1/en
Application filed by Anvar filed Critical Anvar
Publication of DK105477A publication Critical patent/DK105477A/en
Publication of DK151813B publication Critical patent/DK151813B/en
Application granted granted Critical
Publication of DK151813C publication Critical patent/DK151813C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/5555—Muramyl dipeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK105477A 1976-03-10 1977-03-10 METHOD OF ANALOGUE FOR THE PREPARATION OF ESTERS OF N-ACETYL-MURAMYL-L-ALANYL-D-GLUTAMIC ACID AND OF N-ACETYL-MURAMYL-L-ALANYL-D-ISOGLUTAMINE DK151813C (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
FR7606820A FR2343483A1 (en) 1976-03-10 1976-03-10 Immunogical adjuvants for weak vaccine antigens - are (2)-acetamido-deoxy (D)-glucopyranosyl (D)-propionyl (L)-alanyl (D)-glutamic acid esters and (D)-isoglutamines
FR7606820 1976-03-10
GB4559776 1976-11-02
GB4559776 1976-11-02
FR7702646 1977-01-31
FR7702646A FR2369292A1 (en) 1976-11-02 1977-01-31 ADJUSTING AGENTS IMMUNITY

Publications (3)

Publication Number Publication Date
DK105477A DK105477A (en) 1977-09-11
DK151813B DK151813B (en) 1988-01-04
DK151813C true DK151813C (en) 1988-07-04

Family

ID=27250596

Family Applications (1)

Application Number Title Priority Date Filing Date
DK105477A DK151813C (en) 1976-03-10 1977-03-10 METHOD OF ANALOGUE FOR THE PREPARATION OF ESTERS OF N-ACETYL-MURAMYL-L-ALANYL-D-GLUTAMIC ACID AND OF N-ACETYL-MURAMYL-L-ALANYL-D-ISOGLUTAMINE

Country Status (4)

Country Link
CH (1) CH619469A5 (en)
DE (1) DE2710454C2 (en)
DK (1) DK151813C (en)
NL (1) NL7702579A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2442241A2 (en) * 1978-03-20 1980-06-20 Anvar NOVEL ESTER COMPOUNDS OF MURAMYL-PEPTIDE, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, IN PARTICULAR IN THE FORM OF LIPOSOMES
FR2420545A1 (en) * 1978-03-20 1979-10-19 Anvar NEW ESTERS OF N-ACETYL-MURAMYL-AMINOACYL-GLUTAMIC ACID OR SUBSTITUTION DERIVATIVES THEREOF WITH ANTI-INFECTIOUS PROPERTIES AND / OR IMMUNOLOGICAL ADJUVANTS
US7112564B2 (en) * 2003-04-09 2006-09-26 Zylacta Corporation Biodegradable glucosaminemuramyl peptides for apoptosis modulation

Also Published As

Publication number Publication date
DE2710454C2 (en) 1986-03-27
DE2710454A1 (en) 1977-09-22
NL7702579A (en) 1977-09-13
DK105477A (en) 1977-09-11
DK151813B (en) 1988-01-04
CH619469A5 (en) 1980-09-30

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