DK1431391T3 - RANTES-mutanter og terapeutiske anvendelser heraf - Google Patents

RANTES-mutanter og terapeutiske anvendelser heraf

Info

Publication number
DK1431391T3
DK1431391T3 DK03027936T DK03027936T DK1431391T3 DK 1431391 T3 DK1431391 T3 DK 1431391T3 DK 03027936 T DK03027936 T DK 03027936T DK 03027936 T DK03027936 T DK 03027936T DK 1431391 T3 DK1431391 T3 DK 1431391T3
Authority
DK
Denmark
Prior art keywords
rantes
therapeutic uses
rantes mutants
mutants
wild
Prior art date
Application number
DK03027936T
Other languages
Danish (da)
English (en)
Inventor
Paolo Lusso
Simona Polo
Original Assignee
San Raffaele Centro Fond
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI972865 external-priority patent/IT1297015B1/it
Priority claimed from IT98MI001866 external-priority patent/IT1302012B1/it
Application filed by San Raffaele Centro Fond filed Critical San Raffaele Centro Fond
Application granted granted Critical
Publication of DK1431391T3 publication Critical patent/DK1431391T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK03027936T 1997-12-23 1998-12-21 RANTES-mutanter og terapeutiske anvendelser heraf DK1431391T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI972865 IT1297015B1 (it) 1997-12-23 1997-12-23 Mutanti di rantes e loro applicazioni terapeutiche
IT98MI001866 IT1302012B1 (it) 1998-08-07 1998-08-07 Derivati di rantes e loro applicazioni terapeutiche.
EP98966650A EP1040191B1 (de) 1997-12-23 1998-12-21 Rantes mutanten und deren therapeutische verwendungen

Publications (1)

Publication Number Publication Date
DK1431391T3 true DK1431391T3 (da) 2005-12-19

Family

ID=26331556

Family Applications (2)

Application Number Title Priority Date Filing Date
DK98966650T DK1040191T3 (da) 1997-12-23 1998-12-21 RANTES-mutanter og terapeutiske anvendelser heraf
DK03027936T DK1431391T3 (da) 1997-12-23 1998-12-21 RANTES-mutanter og terapeutiske anvendelser heraf

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK98966650T DK1040191T3 (da) 1997-12-23 1998-12-21 RANTES-mutanter og terapeutiske anvendelser heraf

Country Status (10)

Country Link
US (2) US6608177B1 (de)
EP (2) EP1431391B1 (de)
JP (1) JP4323094B2 (de)
AT (2) ATE308617T1 (de)
AU (1) AU2415599A (de)
CA (1) CA2316447C (de)
DE (2) DE69832216T2 (de)
DK (2) DK1040191T3 (de)
ES (2) ES2247475T3 (de)
WO (1) WO1999033989A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743594B1 (en) 1995-06-06 2004-06-01 Human Genome Sciences, Inc. Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5)
US6025154A (en) 1995-06-06 2000-02-15 Human Genome Sciences, Inc. Polynucleotides encoding human G-protein chemokine receptor HDGNR10
UA77950C2 (en) * 2000-10-04 2007-02-15 Applied Research Systems Use of mutants of cc chemokines for treatment of multiple sclerosis
IL162600A0 (en) 2001-12-17 2005-11-20 Applied Research Systems Cc-chemokine mutants as cc-chemokine antagonists
PT1494703E (pt) * 2002-04-04 2006-05-31 Applied Research Systems Quimiocinas mutantes que apresentam uma disponibilidade biologica oral melhorada
US7981410B2 (en) * 2006-11-13 2011-07-19 Functional Genetics, Inc. Therapeutic targeting of escort proteins
MX2010001307A (es) 2007-08-02 2010-07-30 Novimmune Sa Anticuerpos anti-proteína regulada con la activación, expresada y secretada por los linfocitos t normales y metodos de uso de los mismos.
CA3101052A1 (en) 2018-05-28 2019-12-05 ORION Biotechnology Switzerland Sarl Methods of inhibiting cerebral inflammation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9703889A (es) * 1994-12-08 1997-08-30 Glaxo Group Ltd Peptido rantes y fragmentos y composiciones que lo contienen, para el tratamiento de la inflamacion.
FR2748938B1 (fr) * 1996-05-22 1998-07-31 Pasteur Institut Utilisation de molecules antagonistes de chemokines pour leur activite antivirale notamment contre un retrovirus de type vih
AU4561497A (en) * 1996-09-25 1998-04-17 British Biotech Pharmaceuticals Limited Human rantes mutants incapable of aggregate formation

Also Published As

Publication number Publication date
DE69832197T2 (de) 2006-05-24
ATE308616T1 (de) 2005-11-15
US20030216549A1 (en) 2003-11-20
DK1040191T3 (da) 2005-12-19
EP1040191B1 (de) 2005-11-02
EP1431391B1 (de) 2005-11-02
WO1999033989A3 (en) 1999-08-26
JP2002507388A (ja) 2002-03-12
ATE308617T1 (de) 2005-11-15
WO1999033989A2 (en) 1999-07-08
DE69832216D1 (de) 2005-12-08
DE69832197D1 (de) 2005-12-08
EP1431391A3 (de) 2004-10-06
JP4323094B2 (ja) 2009-09-02
ES2247475T3 (es) 2006-03-01
US7164000B2 (en) 2007-01-16
CA2316447A1 (en) 1999-07-08
DE69832216T2 (de) 2006-05-24
EP1040191A2 (de) 2000-10-04
AU2415599A (en) 1999-07-19
EP1431391A2 (de) 2004-06-23
CA2316447C (en) 2009-07-28
ES2247738T3 (es) 2006-03-01
US6608177B1 (en) 2003-08-19

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