DK138418B - Analogifremgangsmåde til fremstilling af 3-hydroxy-alfa-(1-aminoethyl)-benzylalkohol-derivater eller syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af 3-hydroxy-alfa-(1-aminoethyl)-benzylalkohol-derivater eller syreadditionssalte deraf.

Info

Publication number
DK138418B
DK138418B DK358870AA DK358870A DK138418B DK 138418 B DK138418 B DK 138418B DK 358870A A DK358870A A DK 358870AA DK 358870 A DK358870 A DK 358870A DK 138418 B DK138418 B DK 138418B
Authority
DK
Denmark
Prior art keywords
aminoethyl
alpha
hydroxy
preparation
acid addition
Prior art date
Application number
DK358870AA
Other languages
Danish (da)
English (en)
Other versions
DK138418C (fr
Inventor
Walfred S Saari
Charles Stewart Miller
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK138418B publication Critical patent/DK138418B/da
Application granted granted Critical
Publication of DK138418C publication Critical patent/DK138418C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK358870AA 1969-07-10 1970-07-09 Analogifremgangsmåde til fremstilling af 3-hydroxy-alfa-(1-aminoethyl)-benzylalkohol-derivater eller syreadditionssalte deraf. DK138418B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84512069A 1969-07-10 1969-07-10

Publications (2)

Publication Number Publication Date
DK138418B true DK138418B (da) 1978-09-04
DK138418C DK138418C (fr) 1979-02-12

Family

ID=25294452

Family Applications (1)

Application Number Title Priority Date Filing Date
DK358870AA DK138418B (da) 1969-07-10 1970-07-09 Analogifremgangsmåde til fremstilling af 3-hydroxy-alfa-(1-aminoethyl)-benzylalkohol-derivater eller syreadditionssalte deraf.

Country Status (14)

Country Link
US (1) US3714229A (fr)
JP (1) JPS5220463B1 (fr)
AU (1) AU1710070A (fr)
BE (1) BE753237A (fr)
BR (1) BR6914798D0 (fr)
CH (1) CH565138A5 (fr)
DK (1) DK138418B (fr)
ES (1) ES381597A1 (fr)
FR (1) FR2059503B1 (fr)
GB (1) GB1273653A (fr)
IL (1) IL34831A0 (fr)
NL (1) NL7009390A (fr)
SE (1) SE383511B (fr)
ZA (1) ZA704157B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138581A (en) * 1969-04-01 1979-02-06 Sterling Drugs Inc. 3(Hydroxy or hydroxymethyl)-4(hydroxy)-α-(aminomethyl)benzyl alcohols
US4336400A (en) * 1969-04-01 1982-06-22 Sterling Drug Inc. 3-(Hydroxy or hydroxymethyl)-4-hydroxy-alpha(aminomethyl)benzyl alcohols and methods of use
GB1346401A (en) * 1971-05-12 1974-02-13 Lepetit Spa Cardioactive arylaminobutanols
US3928426A (en) * 1972-01-28 1975-12-23 Robins Co Inc A H 1-Cyclopropyl-1-phenyl-omega-amino-1-lower alkanoyloxyalkanes
US4001429A (en) * 1974-04-01 1977-01-04 A. H. Robins Company, Incorporated 1-Cyclopropyl-1-phenyl-ω-amino-1-alkanols and 1-lower-alkylacyl derivatives as analgetics
JPS556625B2 (fr) * 1974-05-16 1980-02-18
JPS52171571U (fr) * 1976-06-16 1977-12-27
JPS53114564U (fr) * 1977-02-16 1978-09-12
DE2817494A1 (de) * 1977-05-03 1978-11-09 Continental Pharma Aminoalkohol-derivat
JPS6210048A (ja) * 1985-07-04 1987-01-19 Microbial Chem Res Found 新規生理活性物質ｍｈ４３５
US5220063A (en) * 1991-05-10 1993-06-15 Hoechst Celanese Corporation Method for the preparation of arylalkanolacylamides
CN116332774A (zh) * 2023-03-29 2023-06-27 成都瑞尔医药科技有限公司 一种高手性纯度的重酒石酸间羟胺的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2442797A (en) * 1943-10-05 1948-06-08 Sharp & Dohme Inc Para-amino benzoic acid esters
FR1537803A (fr) * 1966-07-14 1968-08-30 Diwag Chemische Fabriken Gmbh Procédé pour fabriquer des acylaminophénolalcanols

Also Published As

Publication number Publication date
JPS5220463B1 (fr) 1977-06-03
FR2059503B1 (fr) 1973-07-13
BE753237A (fr) 1971-01-11
SE383511B (sv) 1976-03-15
NL7009390A (fr) 1971-01-12
GB1273653A (en) 1972-05-10
BR6914798D0 (pt) 1973-03-08
ZA704157B (en) 1972-01-26
CH565138A5 (fr) 1975-08-15
US3714229A (en) 1973-01-30
AU1710070A (en) 1972-01-06
FR2059503A1 (fr) 1971-06-04
ES381597A1 (es) 1973-04-16
DE2034139A1 (de) 1971-02-04
IL34831A0 (en) 1970-09-17
DK138418C (fr) 1979-02-12

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