DK1383516T3 - Indgivelse af et polysaccharid samtidig med et kemoterapeutisk middel til behandling af cancer - Google Patents

Indgivelse af et polysaccharid samtidig med et kemoterapeutisk middel til behandling af cancer

Info

Publication number
DK1383516T3
DK1383516T3 DK02731178.6T DK02731178T DK1383516T3 DK 1383516 T3 DK1383516 T3 DK 1383516T3 DK 02731178 T DK02731178 T DK 02731178T DK 1383516 T3 DK1383516 T3 DK 1383516T3
Authority
DK
Denmark
Prior art keywords
polysaccharide
cancer
concomitantly
administration
treatment
Prior art date
Application number
DK02731178.6T
Other languages
Danish (da)
English (en)
Inventor
Anatole Klyosov
David Platt
Original Assignee
Pro Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/818,596 external-priority patent/US6645946B1/en
Application filed by Pro Pharmaceuticals Inc filed Critical Pro Pharmaceuticals Inc
Application granted granted Critical
Publication of DK1383516T3 publication Critical patent/DK1383516T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK02731178.6T 2001-03-27 2002-03-27 Indgivelse af et polysaccharid samtidig med et kemoterapeutisk middel til behandling af cancer DK1383516T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/818,596 US6645946B1 (en) 2001-03-27 2001-03-27 Delivery of a therapeutic agent in a formulation for reduced toxicity
US31709201P 2001-09-04 2001-09-04
PCT/US2002/009524 WO2002076474A1 (en) 2001-03-27 2002-03-27 Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer

Publications (1)

Publication Number Publication Date
DK1383516T3 true DK1383516T3 (da) 2012-02-20

Family

ID=26980760

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02731178.6T DK1383516T3 (da) 2001-03-27 2002-03-27 Indgivelse af et polysaccharid samtidig med et kemoterapeutisk middel til behandling af cancer

Country Status (7)

Country Link
US (1) US7012068B2 (enExample)
EP (1) EP1383516B1 (enExample)
JP (1) JP4744782B2 (enExample)
AT (1) ATE532524T1 (enExample)
DK (1) DK1383516T3 (enExample)
ES (1) ES2376739T3 (enExample)
WO (1) WO2002076474A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6680306B2 (en) 2001-06-21 2004-01-20 Glycogenesys, Inc. Method for enhancing the effectiveness of cancer therapies
US20040223971A1 (en) * 2003-04-07 2004-11-11 Glycogenesys, Inc. Composition and uses of galectin antagonists
US20050053664A1 (en) * 2003-09-08 2005-03-10 Eliezer Zomer Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer
WO2005037293A1 (en) * 2003-10-16 2005-04-28 Univ Monash Immunomodulating compositions and uses therefor
KR20060127874A (ko) * 2003-12-12 2006-12-13 타이요 카가꾸 가부시키가이샤 장질환 개선용 조성물
JP2008503583A (ja) * 2004-06-22 2008-02-07 プロ−ファーマシューティカルズ，インコーポレイティド 抗がん薬、抗血管形成薬、及び多糖類を共デリバリーするための組成物及び方法
US20080286251A1 (en) * 2004-08-02 2008-11-20 Propharmaceuticals, Inc. Compositions and Methods for the Enhancement of Chemotherapy with Microbial Cytotoxins
WO2008011216A2 (en) 2006-05-16 2008-01-24 Pro-Pharmaceuticals, Inc. Galactose-pronged polysaccharides in a formulation for antifibrotic therapies
WO2011016811A1 (en) * 2009-08-07 2011-02-10 Pro-Pharmaceuticals, Inc. Methods for reducing the incidence of chemotherapy - induced mucositis
US8604187B2 (en) * 2010-01-14 2013-12-10 North Texas Medical Associates Compositions and methods of aloe polysaccharides
ES2698101T3 (es) 2012-10-10 2019-01-31 Galectin Therapeutics Inc Compuestos de carbohidrato con restos de galactosa para el tratamiento de la nefropatía diabética y trastornos asociados
US9339515B2 (en) 2013-02-20 2016-05-17 Galectin Therapeutics, Inc. Method for treatment of pulmonary fibrosis
CA3102155A1 (en) 2018-06-29 2020-01-02 Glykos Biomedical Oy Conjugates
WO2021123506A1 (en) 2019-12-18 2021-06-24 Glykos Biomedical Oy Stabile conjugate

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5308838A (en) * 1982-05-07 1994-05-03 Carrington Laboratories, Inc. Uses of aloe products
US5118673A (en) * 1982-05-07 1992-06-02 Carrington Laboratories, Inc. Uses of aloe products
WO1993008810A1 (en) * 1991-11-05 1993-05-13 Carrington Laboratories, Inc. Uses of aloe products, e.g. acemannan, in the treatment of diseases requiring intervention of the immune system for cure
JP3801658B2 (ja) 1993-03-02 2006-07-26 太陽化学株式会社 β−グルクロニダーゼ活性抑制組成物
GB9412394D0 (en) 1994-06-21 1994-08-10 Danbiosyst Uk Colonic drug delivery composition
US5834442A (en) * 1994-07-07 1998-11-10 Barbara Ann Karmanos Cancer Institute Method for inhibiting cancer metastasis by oral administration of soluble modified citrus pectin
WO1996004014A1 (en) 1994-07-29 1996-02-15 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Controlled-release drug preparation
US5861142A (en) * 1996-03-25 1999-01-19 Schick; Mary Pichler Method for promoting hair, nail, and skin keratinization
WO1998050018A1 (en) * 1997-05-06 1998-11-12 Xiao Yu Wu Drug delivery system
NZ507211A (en) 1998-03-26 2003-07-25 Fujisawa Pharmaceutical Co Sustained release preparations
KR20000011247A (ko) * 1998-07-23 2000-02-25 김윤 다당류를이용한대장선택성약물전달조성물및약학제제
ID28275A (id) 1998-09-28 2001-05-10 Warner Lambert Co Penghantaran kolon dan enterik yang menggunakan kapsul-kapsul hpmc
WO2000059481A1 (en) 1999-04-06 2000-10-12 Pharmaquest Ltd. PHARMACEUTICAL DOSAGE FORM FOR PULSATILE DELIVERY OF d-threo-METHYLPHENIDATE AND A SECOND CNS STIMULANT

Also Published As

Publication number Publication date
EP1383516A4 (en) 2007-08-01
US7012068B2 (en) 2006-03-14
JP4744782B2 (ja) 2011-08-10
EP1383516B1 (en) 2011-11-09
JP2004525143A (ja) 2004-08-19
US20030064957A1 (en) 2003-04-03
ES2376739T3 (es) 2012-03-16
WO2002076474A1 (en) 2002-10-03
ATE532524T1 (de) 2011-11-15
EP1383516A1 (en) 2004-01-28

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