DK1315729T3 - Forbindelser i form af homo- eller heterodimere prolægemidler; fremgangsmåder til opnåelse af disse prolægemidler og deres farmaceutiske acceptable salte og anvendelse af forbindelser ved behandling af phosphordiesterease-medierede sygdomme eller .... - Google Patents
Forbindelser i form af homo- eller heterodimere prolægemidler; fremgangsmåder til opnåelse af disse prolægemidler og deres farmaceutiske acceptable salte og anvendelse af forbindelser ved behandling af phosphordiesterease-medierede sygdomme eller ....Info
- Publication number
- DK1315729T3 DK1315729T3 DK01953709T DK01953709T DK1315729T3 DK 1315729 T3 DK1315729 T3 DK 1315729T3 DK 01953709 T DK01953709 T DK 01953709T DK 01953709 T DK01953709 T DK 01953709T DK 1315729 T3 DK1315729 T3 DK 1315729T3
- Authority
- DK
- Denmark
- Prior art keywords
- sub
- prodrugs
- compounds
- homo
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0003386A BRPI0003386B8 (pt) | 2000-08-08 | 2000-08-08 | pró-droga homo ou heterodiméricas úteis no tratamento de doenças ou disfunções mediadas por fosfodiesterases; composições farmacêuticas contendo a pró-droga ou seus sais farmacêuticos aceitáveis; processo de obtenção destas pró-drogas |
| PCT/BR2001/000096 WO2002012241A1 (en) | 2000-08-08 | 2001-08-07 | Compounds in the form of homodimeric, heterodimeric and/or homo and heteromultimeric pro-drugs; process for obtaining these pro-drugs and their acceptable pharmaceutical salts and use of compounds in the treatment of phosphodiesterasis-mediated diseases or dysfunction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1315729T3 true DK1315729T3 (da) | 2008-05-26 |
Family
ID=3944849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01953709T DK1315729T3 (da) | 2000-08-08 | 2001-08-07 | Forbindelser i form af homo- eller heterodimere prolægemidler; fremgangsmåder til opnåelse af disse prolægemidler og deres farmaceutiske acceptable salte og anvendelse af forbindelser ved behandling af phosphordiesterease-medierede sygdomme eller .... |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7148350B2 (de) |
| EP (1) | EP1315729B1 (de) |
| AT (1) | ATE383363T1 (de) |
| AU (1) | AU2001276200A1 (de) |
| BR (1) | BRPI0003386B8 (de) |
| DE (1) | DE60132339T2 (de) |
| DK (1) | DK1315729T3 (de) |
| ES (1) | ES2299497T3 (de) |
| HK (1) | HK1058189A1 (de) |
| WO (1) | WO2002012241A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200719916A (en) * | 2005-04-12 | 2007-06-01 | Psivida Inc | HMGCoA reductase inhibitor combinations and uses thereof |
| EP1909848A2 (de) * | 2005-08-01 | 2008-04-16 | PSivida Inc. | Hmgcoa-reduktase-inhibitor-angiotensin zur umwandlung von enzym-inhibitor-verbindungen |
| JP2009184981A (ja) * | 2008-02-07 | 2009-08-20 | Shiseido Co Ltd | 抗ｄ−アミノ酸モノクローナル抗体及び、抗ｄ−アミノ酸モノクローナル抗体を用いたｄ−アミノ酸の免疫学的分析方法 |
| WO2015093924A1 (es) * | 2013-12-19 | 2015-06-25 | CASTRO ALDRETE, Jorge Issac | Vehículo para la administración de compuestos farmacéuticos |
| CN109658984B (zh) * | 2018-12-18 | 2021-12-03 | 北京深度制耀科技有限公司 | 一种信息推荐和信息推荐模型训练方法、相关装置 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4127118B1 (en) | 1977-03-16 | 1995-12-19 | Alvaro Latorre | Method of effecting and enhancing an erection |
| US4631190A (en) | 1981-06-26 | 1986-12-23 | Shen Wei C | Acidity-sensitive spacer molecule to control the release of pharmaceuticals from molecular carriers |
| US4997913A (en) | 1986-06-30 | 1991-03-05 | Oncogen | pH-sensitive immunoconjugates and methods for their use in tumor therapy |
| US4863911A (en) | 1986-08-04 | 1989-09-05 | University Of Florida | Method for treating male sexual dysfunction |
| US4801587A (en) | 1987-03-02 | 1989-01-31 | Gene Voss | Impotence ointment |
| US5059603A (en) | 1989-06-12 | 1991-10-22 | Centuries Laboratories, Inc. | Method and composition for treating impotence |
| US5140013A (en) | 1989-11-28 | 1992-08-18 | Universite Laval | Maleic anhydride derivatives used as conjugation agents of anti-tumor agents on desired carriers |
| FI101678B (fi) | 1990-12-31 | 1998-08-14 | Akzo Nv | Happolabiileja kytkentämolekyylejä |
| SE9103701D0 (sv) * | 1991-12-13 | 1991-12-13 | Kabi Pharmacia Ab | Apolipoprotein |
| GB9311920D0 (en) * | 1993-06-09 | 1993-07-28 | Pfizer Ltd | Therapeutic agents |
| US6051576A (en) * | 1994-01-28 | 2000-04-18 | University Of Kentucky Research Foundation | Means to achieve sustained release of synergistic drugs by conjugation |
| ES2129893T3 (es) | 1994-07-15 | 1999-06-16 | Biosearch Italia Spa | Dinucleosido-5',5'-pirofosfatos. |
| US5731339A (en) | 1995-04-28 | 1998-03-24 | Zonagen, Inc. | Methods and formulations for modulating the human sexual response |
| US6031096A (en) | 1997-05-15 | 2000-02-29 | Drug Innovation & Design, Inc. | Acyclovir diester derivatives |
| US6037346A (en) | 1997-10-28 | 2000-03-14 | Vivus, Inc. | Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
| US6030997A (en) | 1998-01-21 | 2000-02-29 | Eilat; Eran | Acid labile prodrugs |
| AU4068599A (en) | 1998-05-20 | 1999-12-06 | Schering Corporation | Combination of phentolamine and cyclic gmp phosphodiesterase inhibitors for the treatment of sexual dysfunction |
| US6124461A (en) | 1998-05-26 | 2000-09-26 | Saint Louis University, Health Services Center, Research Administration | Compounds, compositions, and methods for treating erectile dysfunction |
| CA2319495A1 (en) * | 1998-06-08 | 1999-12-16 | Advanced Medicine, Inc. | Multibinding inhibitors of microsomal triglyceride transferase protein |
| US6265420B1 (en) | 1998-06-23 | 2001-07-24 | Medinox, Inc. | Use of nitric oxide scavengers to treat side effects caused by therapeutic administration of sources of nitric oxide |
| US6200591B1 (en) | 1998-06-25 | 2001-03-13 | Anwar A. Hussain | Method of administration of sildenafil to produce instantaneous response for the treatment of erectile dysfunction |
| WO2000000199A1 (en) | 1998-06-26 | 2000-01-06 | Nastech Pharmaceutical Company, Inc. | Nasal delivery of sildenafil citrate |
| DE19834505A1 (de) | 1998-07-31 | 2000-02-03 | Hexal Ag | Transdermales therapeutisches System zur Anwendung von Sildenafil |
| DE19834507A1 (de) | 1998-07-31 | 2000-02-03 | Hexal Ag | Pharmazeutische, wasserlösliche Tablettenformulierung zur Anwendung von Sildenafil |
| DE19834506A1 (de) | 1998-07-31 | 2000-02-03 | Hexal Ag | Transmucosales therapeutisches System zur Anwendung von Sildenafil |
-
2000
- 2000-08-08 BR BRPI0003386A patent/BRPI0003386B8/pt not_active IP Right Cessation
-
2001
- 2001-08-07 EP EP01953709A patent/EP1315729B1/de not_active Expired - Lifetime
- 2001-08-07 DE DE60132339T patent/DE60132339T2/de not_active Expired - Lifetime
- 2001-08-07 WO PCT/BR2001/000096 patent/WO2002012241A1/en active IP Right Grant
- 2001-08-07 DK DK01953709T patent/DK1315729T3/da active
- 2001-08-07 AT AT01953709T patent/ATE383363T1/de active
- 2001-08-07 US US10/362,602 patent/US7148350B2/en not_active Expired - Fee Related
- 2001-08-07 ES ES01953709T patent/ES2299497T3/es not_active Expired - Lifetime
- 2001-08-07 AU AU2001276200A patent/AU2001276200A1/en not_active Abandoned
-
2003
- 2003-12-04 HK HK03108868A patent/HK1058189A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US7148350B2 (en) | 2006-12-12 |
| EP1315729A1 (de) | 2003-06-04 |
| WO2002012241A8 (en) | 2003-12-04 |
| WO2002012241A1 (en) | 2002-02-14 |
| BR0003386A (pt) | 2004-07-06 |
| EP1315729A4 (de) | 2004-07-07 |
| ATE383363T1 (de) | 2008-01-15 |
| HK1058189A1 (en) | 2004-05-07 |
| US20040106629A1 (en) | 2004-06-03 |
| BRPI0003386B8 (pt) | 2021-05-25 |
| DE60132339T2 (de) | 2008-12-24 |
| ES2299497T3 (es) | 2008-06-01 |
| AU2001276200A1 (en) | 2002-02-18 |
| BRPI0003386B1 (pt) | 2016-10-11 |
| DE60132339D1 (de) | 2008-02-21 |
| EP1315729B1 (de) | 2008-01-09 |
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