DK130847B - Process for the preparation of an antibiotic active substance containing antibiotic G-418, and optionally verdamicin I, gentamicin A and sisomycin, the individual components antibiotic G-418 and optionally verdamicin I, gentamicin A and sisomicin or salts or Schiff-base-oxazolidine derivatives thereof. - Google Patents

Process for the preparation of an antibiotic active substance containing antibiotic G-418, and optionally verdamicin I, gentamicin A and sisomycin, the individual components antibiotic G-418 and optionally verdamicin I, gentamicin A and sisomicin or salts or Schiff-base-oxazolidine derivatives thereof.

Info

Publication number
DK130847B
DK130847B DK407772AA DK407772A DK130847B DK 130847 B DK130847 B DK 130847B DK 407772A A DK407772A A DK 407772AA DK 407772 A DK407772 A DK 407772A DK 130847 B DK130847 B DK 130847B
Authority
DK
Denmark
Prior art keywords
antibiotic
verdamicin
gentamicin
optionally
sisomycin
Prior art date
Application number
DK407772AA
Other languages
Danish (da)
Other versions
DK130847C (en
Inventor
M J Weinstein
G H Wagman
R Testa
J A Marquez
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of DK130847B publication Critical patent/DK130847B/en
Application granted granted Critical
Publication of DK130847C publication Critical patent/DK130847C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK407772AA 1971-11-08 1972-08-17 Process for the preparation of an antibiotic active substance containing antibiotic G-418, and optionally verdamicin I, gentamicin A and sisomycin, the individual components antibiotic G-418 and optionally verdamicin I, gentamicin A and sisomicin or salts or Schiff-base-oxazolidine derivatives thereof. DK130847B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19670771A 1971-11-08 1971-11-08

Publications (2)

Publication Number Publication Date
DK130847B true DK130847B (en) 1975-04-21
DK130847C DK130847C (en) 1975-09-29

Family

ID=22726520

Family Applications (1)

Application Number Title Priority Date Filing Date
DK407772AA DK130847B (en) 1971-11-08 1972-08-17 Process for the preparation of an antibiotic active substance containing antibiotic G-418, and optionally verdamicin I, gentamicin A and sisomycin, the individual components antibiotic G-418 and optionally verdamicin I, gentamicin A and sisomicin or salts or Schiff-base-oxazolidine derivatives thereof.

Country Status (20)

Country Link
JP (1) JPS4852991A (en)
AR (1) AR193286A1 (en)
AT (1) AT319469B (en)
BE (1) BE787758A (en)
CA (1) CA972303A (en)
CH (1) CH586281A5 (en)
CS (1) CS163282B2 (en)
DD (1) DD102161A5 (en)
DE (1) DE2239964A1 (en)
DK (1) DK130847B (en)
FR (1) FR2159246A1 (en)
IL (1) IL40151A (en)
LU (1) LU65922A1 (en)
NL (1) NL7211265A (en)
NO (1) NO136050C (en)
OA (1) OA04260A (en)
PH (1) PH13016A (en)
PL (1) PL84893B1 (en)
RO (1) RO58761A (en)
SE (1) SE384691B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2349974A1 (en) * 1972-10-10 1974-04-18 Scherico Ltd PSEUDODI- AND TRISACCHARIDES AND THE PROCESS FOR THEIR PRODUCTION

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7012428A (en) * 1969-08-25 1971-03-01
DE2130113C3 (en) * 1970-06-22 1980-07-03 Scherico Ltd., Luzern (Schweiz) Gentamicin B, gentamicin B1 and gentamicin X, processes for their production and pharmaceutical preparations containing these gentamicins

Also Published As

Publication number Publication date
JPS4852991A (en) 1973-07-25
OA04260A (en) 1979-12-31
FR2159246B1 (en) 1976-03-05
PL84893B1 (en) 1976-04-30
LU65922A1 (en) 1973-01-15
NO136050B (en) 1977-04-04
CH586281A5 (en) 1977-03-31
PH13016A (en) 1979-11-09
DK130847C (en) 1975-09-29
NO136050C (en) 1977-07-13
FR2159246A1 (en) 1973-06-22
IL40151A0 (en) 1972-10-29
DE2239964A1 (en) 1973-06-14
CS163282B2 (en) 1975-08-29
BE787758A (en) 1973-02-19
NL7211265A (en) 1973-05-10
AT319469B (en) 1974-12-27
AR193286A1 (en) 1973-04-11
CA972303A (en) 1975-08-05
RO58761A (en) 1975-12-15
SE384691B (en) 1976-05-17
IL40151A (en) 1976-01-30
DD102161A5 (en) 1973-12-05

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