DK124336B - Fremgangsmåde til fremstilling af de antibiotiske stoffer (-)(cis-1,2-epoxypropyl)-phosphonsyre eller et salt heraf. - Google Patents

Fremgangsmåde til fremstilling af de antibiotiske stoffer (-)(cis-1,2-epoxypropyl)-phosphonsyre eller et salt heraf.

Info

Publication number
DK124336B
DK124336B DK357368AA DK357368A DK124336B DK 124336 B DK124336 B DK 124336B DK 357368A A DK357368A A DK 357368AA DK 357368 A DK357368 A DK 357368A DK 124336 B DK124336 B DK 124336B
Authority
DK
Denmark
Prior art keywords
epoxypropyl
cis
salt
preparation
phosphonic acid
Prior art date
Application number
DK357368AA
Other languages
Danish (da)
English (en)
Inventor
J Mata
Val S Del
D Hendlin
E Stapley
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK124336B publication Critical patent/DK124336B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y10S435/896—Streptomyces fradiae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK357368AA 1967-07-25 1968-07-24 Fremgangsmåde til fremstilling af de antibiotiske stoffer (-)(cis-1,2-epoxypropyl)-phosphonsyre eller et salt heraf. DK124336B (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65575767A 1967-07-25 1967-07-25
US67916567A 1967-10-30 1967-10-30
US72805968A 1968-05-09 1968-05-09

Publications (1)

Publication Number Publication Date
DK124336B true DK124336B (da) 1972-10-09

Family

ID=27417948

Family Applications (1)

Application Number Title Priority Date Filing Date
DK357368AA DK124336B (da) 1967-07-25 1968-07-24 Fremgangsmåde til fremstilling af de antibiotiske stoffer (-)(cis-1,2-epoxypropyl)-phosphonsyre eller et salt heraf.

Country Status (18)

Country Link
US (1) US3639590A (xx)
AT (1) AT290011B (xx)
BE (1) BE718507A (xx)
CH (1) CH521440A (xx)
DE (1) DE1768965B1 (xx)
DK (1) DK124336B (xx)
ES (1) ES356487A1 (xx)
FI (1) FI45863C (xx)
FR (2) FR7683M (xx)
GB (1) GB1223923A (xx)
IL (1) IL30384A (xx)
IT (1) IT1008508B (xx)
LU (1) LU56580A1 (xx)
MT (1) MTP565B (xx)
NL (1) NL143130B (xx)
NO (1) NO127758B (xx)
SE (1) SE367020B (xx)
YU (1) YU33669B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3873547A (en) * 1973-05-02 1975-03-25 Merck & Co Inc The salt of 3-nitro-9-aminoacridine and -(cis)-1,2-epoxypropylphosphonic acid
IT1112282B (it) * 1978-07-19 1986-01-13 Zambon Spa Bis-(2-ammonio-2-idrossimetil-1,3-propandiolo)(2r-cis)-(3-metilossiranil)fosfonato
IT1124610B (it) * 1979-10-18 1986-05-07 Zambo Spa Mono(2-ammonio-2-idrossimetil-1,3-propandiolo) (2r-cis)-(o-metilossiranil)fosfonato
US4463092A (en) * 1982-09-27 1984-07-31 Eli Lilly And Company Process for production antibiotic A53868
US4482488A (en) * 1982-09-27 1984-11-13 Eli Lilly And Company Antibiotic A53868 and process for production thereof
IT1212777B (it) * 1983-10-07 1989-11-30 Seuref Ag Antibiotica. composto ad attivita'
CH660306A5 (de) * 1984-10-05 1987-04-15 Schering Spa Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2895952A (en) * 1955-04-21 1959-07-21 Merck & Co Inc Purification of novobiocin

Also Published As

Publication number Publication date
YU176368A (en) 1977-06-30
FR7683M (xx) 1970-02-16
ES356487A1 (es) 1970-10-16
GB1223923A (en) 1971-03-03
FR1574556A (xx) 1969-07-11
NL143130B (nl) 1974-09-16
FI45863B (xx) 1972-06-30
NO127758B (xx) 1973-08-13
IL30384A0 (en) 1968-09-26
MTP565B (en) 1969-09-22
LU56580A1 (xx) 1969-05-16
US3639590A (en) 1972-02-01
SE367020B (xx) 1974-05-13
FI45863C (fi) 1972-10-10
AT290011B (de) 1971-05-10
NL6810011A (xx) 1969-01-28
IL30384A (en) 1973-01-30
IT1008508B (it) 1976-11-30
BE718507A (xx) 1969-01-24
YU33669B (en) 1977-12-31
CH521440A (de) 1972-04-15
DE1768965B1 (de) 1971-12-23

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Legal Events

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PUP Patent expired