DK124027B - Analogous process for the preparation of α-phenyl-α- (2-piperidyl) -methanol compounds or acid addition salts or quaternary ammonium salts thereof. - Google Patents

Analogous process for the preparation of α-phenyl-α- (2-piperidyl) -methanol compounds or acid addition salts or quaternary ammonium salts thereof.

Info

Publication number
DK124027B
DK124027B DK253670AA DK253670A DK124027B DK 124027 B DK124027 B DK 124027B DK 253670A A DK253670A A DK 253670AA DK 253670 A DK253670 A DK 253670A DK 124027 B DK124027 B DK 124027B
Authority
DK
Denmark
Prior art keywords
piperidyl
phenyl
preparation
quaternary ammonium
acid addition
Prior art date
Application number
DK253670AA
Other languages
Danish (da)
Inventor
G Sankey
K Whiting
Original Assignee
Minnesota 3M Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota 3M Lab Ltd filed Critical Minnesota 3M Lab Ltd
Publication of DK124027B publication Critical patent/DK124027B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02Preparation by ring-closure or hydrogenation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK253670AA 1969-05-20 1970-05-19 Analogous process for the preparation of α-phenyl-α- (2-piperidyl) -methanol compounds or acid addition salts or quaternary ammonium salts thereof. DK124027B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2563469 1969-05-20

Publications (1)

Publication Number Publication Date
DK124027B true DK124027B (en) 1972-09-04

Family

ID=10230843

Family Applications (1)

Application Number Title Priority Date Filing Date
DK253670AA DK124027B (en) 1969-05-20 1970-05-19 Analogous process for the preparation of α-phenyl-α- (2-piperidyl) -methanol compounds or acid addition salts or quaternary ammonium salts thereof.

Country Status (12)

Country Link
JP (1) JPS4920787B1 (en)
BE (1) BE750590A (en)
CH (1) CH541557A (en)
DE (1) DE2024049C3 (en)
DK (1) DK124027B (en)
FR (1) FR2051549B1 (en)
GB (1) GB1316424A (en)
IL (1) IL34537A (en)
NL (1) NL169314C (en)
NO (1) NO133448C (en)
SE (1) SE374366B (en)
ZA (1) ZA703208B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA960676A (en) * 1970-05-21 1975-01-07 Smith Kline And French Canada Ltd. 3-sulfonamido-4-hydroxyphenyl-2-piperidinylcarbinols
US5169096A (en) * 1985-07-02 1992-12-08 Merrell Dow Pharmaceuticals Inc. N-aralkyl-piperidine-methanol derivatives
US6004980A (en) * 1990-06-01 1999-12-21 Merrell Pharmaceuticals, Inc. (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
ATE114467T1 (en) * 1990-06-01 1994-12-15 Merrell Dow Pharma (+)-ALPHA-(2,3 DIMETHOXYPHENYL)-1-(2-(FLUOROPHENYL)ETHYL>-4-PIPERIDINEMETHANOL.
US6028083A (en) * 1997-07-25 2000-02-22 Hoechst Marion Roussel, Inc. Esters of (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE569836A (en) *

Also Published As

Publication number Publication date
FR2051549B1 (en) 1974-08-30
DE2024049A1 (en) 1970-12-17
NL169314B (en) 1982-02-01
CH541557A (en) 1973-09-15
FR2051549A1 (en) 1971-04-09
JPS4920787B1 (en) 1974-05-27
NL7007303A (en) 1970-11-24
BE750590A (en) 1970-11-19
NO133448B (en) 1976-01-26
SE374366B (en) 1975-03-03
NL169314C (en) 1982-07-01
IL34537A0 (en) 1970-07-19
ZA703208B (en) 1971-01-27
GB1316424A (en) 1973-05-09
DE2024049B2 (en) 1977-11-24
IL34537A (en) 1973-03-30
NO133448C (en) 1976-05-05
DE2024049C3 (en) 1978-07-20

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Legal Events

Date Code Title Description
PBP Patent lapsed