DK121757B - Process for the preparation of 10,11-dihydro-10,11-dihydroxy-5- (3-substituted aminopropylidene) -5H-dibenzo- [a, d] -cycloheptene compounds. - Google Patents

Process for the preparation of 10,11-dihydro-10,11-dihydroxy-5- (3-substituted aminopropylidene) -5H-dibenzo- [a, d] -cycloheptene compounds.

Info

Publication number
DK121757B
DK121757B DK351165AA DK351165A DK121757B DK 121757 B DK121757 B DK 121757B DK 351165A A DK351165A A DK 351165AA DK 351165 A DK351165 A DK 351165A DK 121757 B DK121757 B DK 121757B
Authority
DK
Denmark
Prior art keywords
aminopropylidene
dibenzo
dihydroxy
dihydro
substituted
Prior art date
Application number
DK351165AA
Other languages
Danish (da)
Inventor
H Hucker
M Christy
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK121757B publication Critical patent/DK121757B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK351165AA 1963-07-22 1965-07-09 Process for the preparation of 10,11-dihydro-10,11-dihydroxy-5- (3-substituted aminopropylidene) -5H-dibenzo- [a, d] -cycloheptene compounds. DK121757B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US296463A US3390179A (en) 1963-07-22 1963-07-22 Novel 10, 11-dihydro-10, 11-dihydroxy-(3-substituted aminopropylidene)-5h-dibenzo [a, d] cycloheptenes
US4847870A 1970-06-22 1970-06-22

Publications (1)

Publication Number Publication Date
DK121757B true DK121757B (en) 1971-11-29

Family

ID=26726156

Family Applications (3)

Application Number Title Priority Date Filing Date
DK362064AA DK127723B (en) 1963-07-22 1964-07-21 Analogous process for the preparation of trans-10,11-dihydro-10,11-dihydroxy-5 (3-dialkylaminopropylidene) -5H-dibenzo [a, d] cycloheptene compounds or acid addition salts thereof.
DK351265AA DK121856B (en) 1963-07-22 1965-07-09 Analogous process for the preparation of 10,11-dihydro-10,11-dihydroxy-5- (3-monosubstituted aminopropylidene) -5H-dibenzo [a, d] -cycloheptene compounds.
DK351165AA DK121757B (en) 1963-07-22 1965-07-09 Process for the preparation of 10,11-dihydro-10,11-dihydroxy-5- (3-substituted aminopropylidene) -5H-dibenzo- [a, d] -cycloheptene compounds.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK362064AA DK127723B (en) 1963-07-22 1964-07-21 Analogous process for the preparation of trans-10,11-dihydro-10,11-dihydroxy-5 (3-dialkylaminopropylidene) -5H-dibenzo [a, d] cycloheptene compounds or acid addition salts thereof.
DK351265AA DK121856B (en) 1963-07-22 1965-07-09 Analogous process for the preparation of 10,11-dihydro-10,11-dihydroxy-5- (3-monosubstituted aminopropylidene) -5H-dibenzo [a, d] -cycloheptene compounds.

Country Status (11)

Country Link
US (2) US3390179A (en)
BE (1) BE650800A (en)
BR (1) BR6460953D0 (en)
CH (1) CH494731A (en)
DE (1) DE1468339A1 (en)
DK (3) DK127723B (en)
FR (2) FR1572128A (en)
GB (4) GB1074085A (en)
IL (2) IL29677A (en)
NL (1) NL6408390A (en)
SE (3) SE332820B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905981A (en) * 1973-10-12 1975-09-16 Research Corp N-dealkylation of tertiary amines
US4089864A (en) * 1974-03-25 1978-05-16 Merck & Co., Inc. 4-(10,11-Dihydro-cis and trans-10,11-dihydroxy-5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidines
US3894032A (en) * 1974-04-10 1975-07-08 Merck & Co Inc 10,11-Furo derivatives of cyproheptadine
US4044143A (en) * 1975-01-30 1977-08-23 Merck & Co., Inc. 10,11-Bis-(hydroxyalkyl) derivatives of cyproheptadine
DE4232173A1 (en) * 1992-09-25 1994-03-31 Bayer Ag 5-oxo-dibenzo (a, d) cyclohepta-1,4-diene

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3234279A (en) * 1962-09-14 1966-02-08 Merck & Co Inc 5-(gamma-amino-propyl- and propylidene-) 5h-dibenzo[a, d]-10-hydroxy-10, 11-dihydrocycloheptenes and amine borane salts thereof

Also Published As

Publication number Publication date
GB1074082A (en) 1967-06-28
GB1074083A (en) 1967-06-28
SE332820B (en) 1971-02-22
DK127723B (en) 1973-12-24
GB1074084A (en) 1967-06-28
FR1572128A (en) 1969-06-27
DK121856B (en) 1971-12-13
IL29677A (en) 1969-01-29
SE320963B (en) 1970-02-23
SE332819B (en) 1971-02-22
IL21665A (en) 1969-01-29
US3660389A (en) 1972-05-02
GB1074085A (en) 1967-06-28
CH494731A (en) 1970-08-15
BR6460953D0 (en) 1973-08-02
BE650800A (en) 1965-01-20
NL6408390A (en) 1965-01-25
DE1468339A1 (en) 1968-12-19
US3390179A (en) 1968-06-25
FR3905M (en) 1966-02-07

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