DK121606B - Fremgangsmåde til fremstilling af substituerede piperaziner eller syreadditionssalte deraf. - Google Patents

Fremgangsmåde til fremstilling af substituerede piperaziner eller syreadditionssalte deraf.

Info

Publication number
DK121606B
DK121606B DK122766A DK122766A DK121606B DK 121606 B DK121606 B DK 121606B DK 122766 A DK122766 A DK 122766A DK 122766 A DK122766 A DK 122766A DK 121606 B DK121606 B DK 121606B
Authority
DK
Denmark
Prior art keywords
preparation
acid addition
addition salts
substituted piperazines
piperazines
Prior art date
Application number
DK122766A
Other languages
Danish (da)
English (en)
Inventor
J Vacher
R Mauvernay
N Busch
Original Assignee
R Mauvernay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by R Mauvernay filed Critical R Mauvernay
Publication of DK121606B publication Critical patent/DK121606B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK122766A 1965-03-09 1966-03-09 Fremgangsmåde til fremstilling af substituerede piperaziner eller syreadditionssalte deraf. DK121606B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9981/65A GB1097572A (en) 1965-03-09 1965-03-09 Novel piperazines for pharmaceutical use

Publications (1)

Publication Number Publication Date
DK121606B true DK121606B (da) 1971-11-08

Family

ID=9882344

Family Applications (1)

Application Number Title Priority Date Filing Date
DK122766A DK121606B (da) 1965-03-09 1966-03-09 Fremgangsmåde til fremstilling af substituerede piperaziner eller syreadditionssalte deraf.

Country Status (11)

Country Link
US (1) US3448192A (xx)
BE (1) BE676842A (xx)
CH (1) CH448100A (xx)
DE (1) DE1595984A1 (xx)
DK (1) DK121606B (xx)
ES (1) ES323532A1 (xx)
FR (1) FR5390M (xx)
GB (1) GB1097572A (xx)
IL (1) IL25219A (xx)
NL (2) NL143925B (xx)
SE (1) SE327406B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
FR2081557B1 (xx) * 1970-03-02 1973-08-10 Cerm Cent Europ Rech Mauvernay
US3755309A (en) * 1971-07-16 1973-08-28 T Takahashi 2-substituted pyridine derivatives and synthesis thereof
DE3139970A1 (de) * 1981-10-08 1983-04-28 Boehringer Mannheim Gmbh, 6800 Mannheim Neue carbonsaeurederivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
FR2543139B1 (fr) * 1983-03-22 1985-08-16 Cerm Cent Europ Rech Mauvernay Derives de (1-alcoxy 2-amino) ethyl pyridine ou pyrazine, leur preparation et leur application en therapeutique
IT1200928B (it) * 1983-07-11 1989-01-27 Malesci Sas Procedimento per la preparazione di 1-piridil-alchil-4-aril piperazine utili per la loro attivita' antiipertensiva,lloro separazione nei relativi antipodi ottici e composti stereoisomeri cosi' ottenuti
EP2027087A2 (en) * 2006-05-18 2009-02-25 MannKind Corporation Intracellular kinase inhibitors
CN101759665B (zh) 2008-12-23 2012-03-28 江苏恩华药业股份有限公司 取代苯基哌嗪芳烷醇衍生物及其在制备镇痛药物中的应用
JP6540505B2 (ja) * 2013-03-29 2019-07-10 国立大学法人 熊本大学 2型糖尿病治療剤

Also Published As

Publication number Publication date
NL143925B (nl) 1974-11-15
FR5390M (xx) 1967-09-18
IL25219A (en) 1970-05-21
NL6602581A (xx) 1966-09-12
BE676842A (xx) 1966-07-18
ES323532A1 (es) 1967-01-01
DE1595984A1 (de) 1970-02-05
US3448192A (en) 1969-06-03
SE327406B (xx) 1970-08-24
NL143925C (xx)
GB1097572A (en) 1968-01-03
CH448100A (fr) 1967-12-15

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