DK120489B - Analogifremgangsmåde til fremstilling af 17α-alkenyl- eller -alkynyl-11,13β-dialkylgon-4-en-3,17β-dioler eller estere deraf. - Google Patents

Analogifremgangsmåde til fremstilling af 17α-alkenyl- eller -alkynyl-11,13β-dialkylgon-4-en-3,17β-dioler eller estere deraf.

Info

Publication number
DK120489B
DK120489B DK582567AA DK582567A DK120489B DK 120489 B DK120489 B DK 120489B DK 582567A A DK582567A A DK 582567AA DK 582567 A DK582567 A DK 582567A DK 120489 B DK120489 B DK 120489B
Authority
DK
Denmark
Prior art keywords
dialkylgon
diols
ene
alkynyl
alkenyl
Prior art date
Application number
DK582567AA
Other languages
Danish (da)
English (en)
Inventor
J Baran
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of DK120489B publication Critical patent/DK120489B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Knives (AREA)
DK582567AA 1966-11-22 1967-11-21 Analogifremgangsmåde til fremstilling af 17α-alkenyl- eller -alkynyl-11,13β-dialkylgon-4-en-3,17β-dioler eller estere deraf. DK120489B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59609066A 1966-11-22 1966-11-22

Publications (1)

Publication Number Publication Date
DK120489B true DK120489B (da) 1971-06-07

Family

ID=24385944

Family Applications (1)

Application Number Title Priority Date Filing Date
DK582567AA DK120489B (da) 1966-11-22 1967-11-21 Analogifremgangsmåde til fremstilling af 17α-alkenyl- eller -alkynyl-11,13β-dialkylgon-4-en-3,17β-dioler eller estere deraf.

Country Status (17)

Country Link
US (1) US3465010A (sv)
AT (1) AT275749B (sv)
BE (1) BE706819A (sv)
CH (1) CH509297A (sv)
DE (1) DE1618980B2 (sv)
DK (1) DK120489B (sv)
ES (1) ES347422A1 (sv)
FI (1) FI45857C (sv)
FR (2) FR1577245A (sv)
GB (1) GB1190240A (sv)
GR (1) GR37269B (sv)
IL (1) IL28982A (sv)
MY (1) MY7300398A (sv)
NL (1) NL160273C (sv)
NO (1) NO126365B (sv)
OA (1) OA02672A (sv)
SE (1) SE337818B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723483A (en) * 1970-07-27 1973-03-27 R Coombs 11{62 -methyl-17{60 -propadienyl steroids
FR2377418A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments
FR2377419A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides 11b-substitues 1,3,5 (10) trieniques, leur procede de preparation et leur application comme medicament
NL7701384A (nl) * 1977-02-10 1978-08-14 Akzo Nv Werkwijze voor het bereiden van nieuwe steroiden van de oestraanreeks.
DE4235220A1 (de) * 1992-10-13 1994-06-16 Schering Ag Gestagen wirksame 19,11ß-überbrückte 4-Estrene
US6037339A (en) 1993-02-08 2000-03-14 Akzo Nobel N.V. C-11 substituted steroids for treating menopausal complaints
ZA94715B (en) * 1993-02-08 1994-10-24 Akzo Nv Steroids for treating menopausal complaints
US5710144A (en) * 1993-02-08 1998-01-20 Akzo Nobel N.V. C-11 substituted steroids for treating menopausal complaints
MXPA02001831A (es) 1999-09-06 2002-10-23 Akzo Nobel Nv Esteroides estrogenicos no aromaticos con un sustituyente de hidrocarburo en posicion 11.
AU8201601A (en) * 2000-07-28 2002-02-13 Akzo Nobel Nv 16alpha-methyl or ethyl substituted estrogens
UA89964C2 (ru) 2004-09-08 2010-03-25 Н.В. Органон 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2843609A (en) * 1955-10-11 1958-07-15 Searle & Co 17-alkenyl and alkynyl derivatives of 4-estrene-3, 17-diol
US3176013A (en) * 1963-07-25 1965-03-30 Searle & Co 17alpha-(aliphatic hydrocarbon)-4, 5-epoxy-19-norandrostane-3beta, 17beta-diols and lower alkanoates thereof
US3346602A (en) * 1966-10-12 1967-10-10 Searle & Co 13beta-alkyl-11-alkylgona-1, 3, 5 (10)-trien-17-ones, ethers and esters thereof

Also Published As

Publication number Publication date
AT275749B (de) 1969-11-10
ES347422A1 (es) 1969-11-01
NL6715790A (sv) 1968-05-24
BE706819A (sv) 1968-05-21
SE337818B (sv) 1971-08-23
IL28982A (en) 1971-12-29
FI45857C (sv) 1972-10-10
DE1618980A1 (de) 1971-04-29
US3465010A (en) 1969-09-02
DE1618980B2 (de) 1976-07-22
GB1190240A (en) 1970-04-29
NL160273C (nl) 1979-10-15
FR7830M (sv) 1970-05-25
OA02672A (fr) 1970-12-15
CH509297A (de) 1971-06-30
NO126365B (sv) 1973-01-29
NL160273B (nl) 1979-05-15
GR37269B (el) 1969-05-12
FI45857B (sv) 1972-06-30
FR1577245A (sv) 1969-08-08
MY7300398A (en) 1973-12-31

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