DK116294B - Analogifremgangsmåde til fremstilling af 4'-demethyl-epipodophyllotoxin. - Google Patents
Analogifremgangsmåde til fremstilling af 4'-demethyl-epipodophyllotoxin.Info
- Publication number
- DK116294B DK116294B DK108468AA DK108468A DK116294B DK 116294 B DK116294 B DK 116294B DK 108468A A DK108468A A DK 108468AA DK 108468 A DK108468 A DK 108468A DK 116294 B DK116294 B DK 116294B
- Authority
- DK
- Denmark
- Prior art keywords
- epipodophyllotoxin
- demethyl
- preparation
- analogous process
- analogous
- Prior art date
Links
- FOVRGQUEGRCWPD-UHFFFAOYSA-N (5aR)-9t-beta-D-Glucopyranosyloxy-5t-(4-hydroxy-3,5-dimethoxy-phenyl)-(5ar,8at)-5,8,8a,9-tetrahydro-5aH-furo[3',4';6,7]naphtho[2,3-d][1,3]dioxol-6-on Natural products COC1=C(O)C(OC)=CC(C2C3=CC=4OCOC=4C=C3C(OC3C(C(O)C(O)C(CO)O3)O)C3C2C(OC3)=O)=C1 FOVRGQUEGRCWPD-UHFFFAOYSA-N 0.000 title 1
- YVCVYCSAAZQOJI-JHQYFNNDSA-N 4'-demethylepipodophyllotoxin Chemical compound COC1=C(O)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@@H](O)[C@@H]3[C@@H]2C(OC3)=O)=C1 YVCVYCSAAZQOJI-JHQYFNNDSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1050964A CH454169A (de) | 1964-08-12 | 1964-08-12 | Verfahren zur Herstellung von neuen Podophyllotoxin-Derivaten |
| CH788865 | 1965-06-04 | ||
| CH819965 | 1965-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK116294B true DK116294B (da) | 1969-12-29 |
Family
ID=27175878
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK490666AA DK111362B (da) | 1964-08-12 | 1966-09-21 | Fremgangsmåde til fremstilling af carbamater af α- eller β-peltatiner |
| DK490566AA DK113368B (da) | 1964-08-12 | 1966-09-21 | Fremgangsmåde til fremstilling af carbamater af forbindelser af lignanrækken. |
| DK108468AA DK116294B (da) | 1964-08-12 | 1968-03-14 | Analogifremgangsmåde til fremstilling af 4'-demethyl-epipodophyllotoxin. |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK490666AA DK111362B (da) | 1964-08-12 | 1966-09-21 | Fremgangsmåde til fremstilling af carbamater af α- eller β-peltatiner |
| DK490566AA DK113368B (da) | 1964-08-12 | 1966-09-21 | Fremgangsmåde til fremstilling af carbamater af forbindelser af lignanrækken. |
Country Status (14)
| Country | Link |
|---|---|
| AT (1) | AT268540B (da) |
| BE (1) | BE668122A (da) |
| BR (1) | BR6572038D0 (da) |
| CH (1) | CH454169A (da) |
| DE (1) | DE1518324A1 (da) |
| DK (3) | DK111362B (da) |
| ES (3) | ES316314A1 (da) |
| FI (1) | FI44410B (da) |
| FR (2) | FR1468767A (da) |
| GB (1) | GB1114123A (da) |
| IL (1) | IL24135A (da) |
| NL (1) | NL6510414A (da) |
| NO (1) | NO119416B (da) |
| OA (1) | OA01792A (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1256336C (zh) * | 2000-11-20 | 2006-05-17 | 金松培 | 新的4′－脱甲基－4′－o－取代的－1－脱氧鬼臼毒衍生物及其几何异构体,制备方法和包含它的抗癌组合物 |
| US7342114B2 (en) | 2003-07-01 | 2008-03-11 | California Pacific Medical Center | Podophyllotoxin derivatives |
| CN112759603B (zh) | 2015-10-27 | 2022-09-09 | 加州太平洋医疗中心 | 鬼臼毒素衍生物及其应用 |
| US10087194B2 (en) | 2015-10-27 | 2018-10-02 | California Pacific Medical Center | Podophyllotoxin derivatives and their use |
-
1964
- 1964-08-12 CH CH1050964A patent/CH454169A/de unknown
-
1965
- 1965-07-30 GB GB32730/65A patent/GB1114123A/en not_active Expired
- 1965-08-06 DE DE19651518324 patent/DE1518324A1/de active Pending
- 1965-08-10 BE BE668122D patent/BE668122A/xx unknown
- 1965-08-10 FR FR27816A patent/FR1468767A/fr not_active Expired
- 1965-08-10 ES ES0316314A patent/ES316314A1/es not_active Expired
- 1965-08-10 NL NL6510414A patent/NL6510414A/xx unknown
- 1965-08-11 IL IL24135A patent/IL24135A/xx unknown
- 1965-08-11 BR BR172038/65A patent/BR6572038D0/pt unknown
- 1965-08-11 FI FI1939/65A patent/FI44410B/fi active
- 1965-08-11 OA OA52144A patent/OA01792A/xx unknown
- 1965-08-11 AT AT823567A patent/AT268540B/de active
- 1965-10-14 ES ES0318460A patent/ES318460A1/es not_active Expired
- 1965-10-14 ES ES0318461A patent/ES318461A1/es not_active Expired
- 1965-11-09 FR FR37802A patent/FR4867M/fr not_active Expired
-
1966
- 1966-09-21 DK DK490666AA patent/DK111362B/da unknown
- 1966-09-21 DK DK490566AA patent/DK113368B/da unknown
- 1966-11-04 NO NO165461A patent/NO119416B/no unknown
-
1968
- 1968-03-14 DK DK108468AA patent/DK116294B/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR1468767A (fr) | 1967-02-10 |
| ES318461A1 (es) | 1966-06-01 |
| CH454169A (de) | 1968-04-15 |
| FR4867M (da) | 1967-02-27 |
| DK113368B (da) | 1969-03-17 |
| NO119416B (da) | 1970-05-19 |
| FI44410B (da) | 1971-08-02 |
| AT268540B (de) | 1969-02-10 |
| NL6510414A (da) | 1966-02-14 |
| DE1518324A1 (de) | 1969-08-21 |
| BR6572038D0 (pt) | 1973-08-16 |
| GB1114123A (en) | 1968-05-15 |
| BE668122A (da) | 1966-02-10 |
| ES318460A1 (es) | 1966-04-01 |
| DK111362B (da) | 1968-08-05 |
| OA01792A (fr) | 1970-01-14 |
| ES316314A1 (es) | 1966-04-16 |
| IL24135A (en) | 1969-02-27 |
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