DK115771B - Fremgangsmåde til fremstilling af (3,5-diamino-6-halogenpyrazinoyl) guanidin- eller (3,5-diamino-6-halogenpyrazinamido) guanidin-forbindelser eller syreadditionssalte deraf. - Google Patents
Fremgangsmåde til fremstilling af (3,5-diamino-6-halogenpyrazinoyl) guanidin- eller (3,5-diamino-6-halogenpyrazinamido) guanidin-forbindelser eller syreadditionssalte deraf.Info
- Publication number
- DK115771B DK115771B DK286467AA DK286467A DK115771B DK 115771 B DK115771 B DK 115771B DK 286467A A DK286467A A DK 286467AA DK 286467 A DK286467 A DK 286467A DK 115771 B DK115771 B DK 115771B
- Authority
- DK
- Denmark
- Prior art keywords
- diamino
- guanidine
- halopyrazinoyl
- halopyrazinamido
- preparation
- Prior art date
Links
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 title 2
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 title 1
- 150000002357 guanidines Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57490966A | 1966-08-25 | 1966-08-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK115771B true DK115771B (da) | 1969-11-10 |
Family
ID=24298146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK286467AA DK115771B (da) | 1966-08-25 | 1967-06-01 | Fremgangsmåde til fremstilling af (3,5-diamino-6-halogenpyrazinoyl) guanidin- eller (3,5-diamino-6-halogenpyrazinamido) guanidin-forbindelser eller syreadditionssalte deraf. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3432502A (de) |
| BE (1) | BE699435A (de) |
| CH (1) | CH484161A (de) |
| DK (1) | DK115771B (de) |
| ES (1) | ES341321A1 (de) |
| GB (1) | GB1184709A (de) |
| NL (1) | NL6707563A (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3506662A (en) * | 1968-04-30 | 1970-04-14 | Merck & Co Inc | Process for preparation of pyrazinoyland pyrazinamidoguanidines |
| US4246406A (en) * | 1979-03-27 | 1981-01-20 | Merck & Co., Inc. | Heterocyclic substituted pyrazinoylguanidines |
| US4224447A (en) * | 1979-03-27 | 1980-09-23 | Merck & Co., Inc. | Novel pyrazinecarboxamides and processes for preparing same |
| EA017919B1 (ru) | 2007-12-10 | 2013-04-30 | Новартис Аг | Производные пиразин-2-карбоксамида для лечения заболеваний, которые поддаются лечению путем блокирования эпителиальных натриевых каналов |
-
1966
- 1966-08-25 US US574909A patent/US3432502A/en not_active Expired - Lifetime
-
1967
- 1967-05-31 NL NL6707563A patent/NL6707563A/xx unknown
- 1967-06-01 DK DK286467AA patent/DK115771B/da unknown
- 1967-06-02 BE BE699435D patent/BE699435A/xx unknown
- 1967-06-02 ES ES341321A patent/ES341321A1/es not_active Expired
- 1967-06-07 CH CH803667A patent/CH484161A/de not_active IP Right Cessation
- 1967-06-07 GB GB26212/67A patent/GB1184709A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE699435A (de) | 1967-12-04 |
| US3432502A (en) | 1969-03-11 |
| NL6707563A (de) | 1968-02-26 |
| GB1184709A (en) | 1970-03-18 |
| ES341321A1 (es) | 1968-10-16 |
| CH484161A (de) | 1970-01-15 |
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