DK1011704T3 - Tumor necrosis factor receptor-derived peptide assays - Google Patents

Tumor necrosis factor receptor-derived peptide assays

Info

Publication number
DK1011704T3
DK1011704T3 DK98923839T DK98923839T DK1011704T3 DK 1011704 T3 DK1011704 T3 DK 1011704T3 DK 98923839 T DK98923839 T DK 98923839T DK 98923839 T DK98923839 T DK 98923839T DK 1011704 T3 DK1011704 T3 DK 1011704T3
Authority
DK
Denmark
Prior art keywords
necrosis factor
tumor necrosis
factor receptor
tnf
derived peptide
Prior art date
Application number
DK98923839T
Other languages
Danish (da)
Inventor
Ramachandran Murali
Mark I Greene
Wataru Takasaki
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Application granted granted Critical
Publication of DK1011704T3 publication Critical patent/DK1011704T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to peptides and peptide analogues designed from a binding loop of a member of the tumor necrosis factor receptor (TNF-R) superfamily. In particular, it relates to cyclic peptides and peptide analogues designed from a binding loop of TNF-R which inhibit TNF binding to its cellular receptors, and methods of making and using such compounds to inhibit the biological activities of TNF.
DK98923839T 1997-05-30 1998-05-29 Tumor necrosis factor receptor-derived peptide assays DK1011704T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/866,545 US6265535B1 (en) 1997-05-30 1997-05-30 Peptides and peptide analogues designed from binding sites of tumor necrosis factor receptor superfamily and their uses
PCT/US1998/010891 WO1998053842A1 (en) 1997-05-30 1998-05-29 Tumor necrosis factor receptor-derived peptide analogues

Publications (1)

Publication Number Publication Date
DK1011704T3 true DK1011704T3 (en) 2007-04-23

Family

ID=25347839

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98923839T DK1011704T3 (en) 1997-05-30 1998-05-29 Tumor necrosis factor receptor-derived peptide assays

Country Status (10)

Country Link
US (1) US6265535B1 (en)
EP (2) EP1011704B1 (en)
AT (1) ATE348106T1 (en)
AU (4) AU744925B2 (en)
CA (1) CA2291963C (en)
DE (1) DE69836638T2 (en)
DK (1) DK1011704T3 (en)
ES (1) ES2279575T3 (en)
PT (1) PT1011704E (en)
WO (1) WO1998053842A1 (en)

Families Citing this family (31)

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Publication number Priority date Publication date Assignee Title
DE19948867A1 (en) * 1998-10-09 2000-08-17 Bioserv Ag Tumor necrosis factor alpha binding peptide comprises 4-9 amino acids
TWI250988B (en) 1998-10-23 2006-03-11 Kirin Amgen Inc Thrombopoietic compounds
US7488590B2 (en) 1998-10-23 2009-02-10 Amgen Inc. Modified peptides as therapeutic agents
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
IL130989A0 (en) * 1999-07-20 2001-01-28 Compugen Ltd Variants of alternative splicing
WO2001008699A1 (en) * 1999-07-28 2001-02-08 The Trustees Of The University Of Pennsylvania Methods of inhibiting osteoclastogenesis
US6673771B1 (en) * 1999-07-28 2004-01-06 The Trustees Of The University Of Pennsylvania Methods of inhibiting osteoclast activity
US6682739B1 (en) * 1999-07-28 2004-01-27 The Trustees Of The University Of Pennsylvania Methods of inhibiting osteoclastogenesis
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
BR0112969A (en) * 2000-08-04 2004-06-22 Dmi Biosciences Inc Method of using diketopiperazines and compositions containing them
US7364736B2 (en) 2001-06-26 2008-04-29 Amgen Inc. Antibodies to OPGL
CA2490542C (en) * 2002-05-23 2013-07-16 Mark I. Greene Fas peptide mimetics and uses thereof
JP2006504406A (en) 2002-06-28 2006-02-09 セントカー・インコーポレーテツド Mammalian CH1-deficient mimetibodies, compositions, methods and uses
WO2004030522A2 (en) * 2002-10-02 2004-04-15 Dmi Biosciences, Inc. Diagnosis and monitoring of diseases
KR20120091266A (en) 2003-05-15 2012-08-17 디엠아이 바이오사이언시스, 인크 Treatment of t-cell mediated diseases
EP1699829A1 (en) * 2003-12-30 2006-09-13 3M Innovative Properties Company Fluoropolymer coagulation method and composition
WO2006010057A2 (en) 2004-07-08 2006-01-26 Amgen Inc. Therapeutic peptides
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
JO3324B1 (en) 2006-04-21 2019-03-13 Amgen Inc Lyophilized Therapeutic Peptibody Formulations
EP2300011A4 (en) 2008-05-27 2012-06-20 Dmi Life Sciences Inc Therapeutic methods and compounds
EP2507267B1 (en) * 2009-12-02 2016-09-14 Acceleron Pharma, Inc. Compositions and methods for increasing serum half-life of fc fusion proteins
WO2012033792A2 (en) 2010-09-07 2012-03-15 Dmi Acquisition Corp. Treatment of diseases
US9376467B2 (en) 2011-03-09 2016-06-28 Jitsubo Co., Ltd. Cross-linked peptides containing non-peptide cross-linked structure, method for synthesizing cross-linked peptides, and novel organic compound used in method
WO2012170938A1 (en) 2011-06-08 2012-12-13 Acceleron Pharma Inc. Compositions and methods for increasing serum half-life
JP6203734B2 (en) 2011-10-10 2017-09-27 アンピオ ファーマシューティカルズ，インコーポレイテッド Treatment of osteoarthritis
BR112014007657A2 (en) 2011-10-10 2017-04-11 Ampio Pharmaceuticals Inc Implantable medical devices with improved immune tolerance and methods for production and implantation
EA201490737A1 (en) 2011-10-28 2014-09-30 Ампио Фармасьютикалз, Инк. TREATMENT OF RHINITIS
WO2014145729A2 (en) 2013-03-15 2014-09-18 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
US9365615B2 (en) 2013-09-09 2016-06-14 Jitsubo Co., Ltd. Cross-linked peptides containing non-peptide cross-linked structure, method for synthesizing cross-linked peptides, and novel organic compound used in method
RU2020136589A (en) 2014-08-18 2020-12-24 Ампио Фармасьютикалз, Инк. TREATMENT OF DEGENERATIVE JOINT DISEASES
WO2016209969A1 (en) 2015-06-22 2016-12-29 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO812612L (en) 1980-08-06 1982-02-08 Ferring Pharma Ltd ENZYME inhibitor.
GB9402331D0 (en) * 1994-02-07 1994-03-30 Univ Mcgill Nerve growth factor structural analogs and their uses

Also Published As

Publication number Publication date
EP1011704A1 (en) 2000-06-28
US6265535B1 (en) 2001-07-24
AU744925B2 (en) 2002-03-07
EP1837344A1 (en) 2007-09-26
ES2279575T3 (en) 2007-08-16
AU7603698A (en) 1998-12-30
DE69836638T2 (en) 2007-10-04
AU4584402A (en) 2002-07-25
EP1011704A4 (en) 2002-07-31
AU2005200634A1 (en) 2005-03-17
AU2008243270A1 (en) 2008-12-11
WO1998053842A1 (en) 1998-12-03
PT1011704E (en) 2007-03-30
AU778124B2 (en) 2004-11-18
CA2291963A1 (en) 1998-12-03
CA2291963C (en) 2011-04-19
ATE348106T1 (en) 2007-01-15
EP1011704B1 (en) 2006-12-13
DE69836638D1 (en) 2007-01-25
AU2008243270B2 (en) 2011-09-01

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