DK1001789T3 - Product comprising at least one double-stranded RNA combined with at least one 6-benzyluracil derivative for simultaneous, separated or time-shifted therapeutic use - Google Patents

Product comprising at least one double-stranded RNA combined with at least one 6-benzyluracil derivative for simultaneous, separated or time-shifted therapeutic use

Info

Publication number
DK1001789T3
DK1001789T3 DK98941526T DK98941526T DK1001789T3 DK 1001789 T3 DK1001789 T3 DK 1001789T3 DK 98941526 T DK98941526 T DK 98941526T DK 98941526 T DK98941526 T DK 98941526T DK 1001789 T3 DK1001789 T3 DK 1001789T3
Authority
DK
Denmark
Prior art keywords
product
benzyluracil
derivative
stranded rna
simultaneous
Prior art date
Application number
DK98941526T
Other languages
Danish (da)
Inventor
Eric Ruhlmann
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Application granted granted Critical
Publication of DK1001789T3 publication Critical patent/DK1001789T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention concerns a product comprising at least a double stranded RNA combined with at least a 6-benzyluracil derivative to be used in therapy simultaneously, separately or spread over time. Said product can be optionally combined with another antiviral agent. Said products are particularly useful for treating AIDS (Acquired Immuno Deficiency Syndrome).
DK98941526T 1997-08-04 1998-08-03 Product comprising at least one double-stranded RNA combined with at least one 6-benzyluracil derivative for simultaneous, separated or time-shifted therapeutic use DK1001789T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9709974A FR2766711B1 (en) 1997-08-04 1997-08-04 PRODUCT COMPRISING AT LEAST ONE DOUBLE-STRANDED RNA IN ASSOCIATION WITH AT LEAST ONE DEVIRE OF 6-BENZYLURACIL FOR SIMULTANEOUS THERAPEUTIC USE, SEPARATE OR SPREAD OVER TIME
PCT/FR1998/001726 WO1999007384A1 (en) 1997-08-04 1998-08-03 Product comprising at least a double stranded rna combined with at least a 6-benzyluracil derivative

Publications (1)

Publication Number Publication Date
DK1001789T3 true DK1001789T3 (en) 2003-03-10

Family

ID=9510012

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98941526T DK1001789T3 (en) 1997-08-04 1998-08-03 Product comprising at least one double-stranded RNA combined with at least one 6-benzyluracil derivative for simultaneous, separated or time-shifted therapeutic use

Country Status (10)

Country Link
EP (1) EP1001789B1 (en)
AT (1) ATE227132T1 (en)
AU (1) AU8987198A (en)
DE (1) DE69809246T2 (en)
DK (1) DK1001789T3 (en)
ES (1) ES2187056T3 (en)
FR (1) FR2766711B1 (en)
NO (1) NO20000554D0 (en)
PT (1) PT1001789E (en)
WO (1) WO1999007384A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4950652A (en) * 1987-03-23 1990-08-21 Hem Research, Inc. dsRNAs for combination therapy in the treatment of viral diseases

Also Published As

Publication number Publication date
PT1001789E (en) 2003-03-31
EP1001789B1 (en) 2002-11-06
FR2766711B1 (en) 2001-02-02
DE69809246D1 (en) 2002-12-12
WO1999007384A1 (en) 1999-02-18
FR2766711A1 (en) 1999-02-05
AU8987198A (en) 1999-03-01
ATE227132T1 (en) 2002-11-15
DE69809246T2 (en) 2003-08-28
ES2187056T3 (en) 2003-05-16
NO20000554L (en) 2000-02-03
NO20000554D0 (en) 2000-02-03
EP1001789A1 (en) 2000-05-24

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