DK0859854T3 - Retrovirale vektorer bærende aldrende celle-afledte inhibitorer 1 (SDI-1) eller antisense SDI-1 nukleotidsekvenser - Google Patents

Retrovirale vektorer bærende aldrende celle-afledte inhibitorer 1 (SDI-1) eller antisense SDI-1 nukleotidsekvenser

Info

Publication number
DK0859854T3
DK0859854T3 DK96934660T DK96934660T DK0859854T3 DK 0859854 T3 DK0859854 T3 DK 0859854T3 DK 96934660 T DK96934660 T DK 96934660T DK 96934660 T DK96934660 T DK 96934660T DK 0859854 T3 DK0859854 T3 DK 0859854T3
Authority
DK
Denmark
Prior art keywords
sdi
retroviral vectors
vectors carrying
antisense
nucleotide sequences
Prior art date
Application number
DK96934660T
Other languages
English (en)
Inventor
H Guenzburg Walter
Michael Saller Robert
Brian Salmons
Original Assignee
Gsf Forschungszentrum Umwelt
Austrian Nordic Biotherapeutic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gsf Forschungszentrum Umwelt, Austrian Nordic Biotherapeutic filed Critical Gsf Forschungszentrum Umwelt
Application granted granted Critical
Publication of DK0859854T3 publication Critical patent/DK0859854T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK96934660T 1995-10-13 1996-10-11 Retrovirale vektorer bærende aldrende celle-afledte inhibitorer 1 (SDI-1) eller antisense SDI-1 nukleotidsekvenser DK0859854T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK115795 1995-10-13
PCT/EP1996/004447 WO1997013867A1 (en) 1995-10-13 1996-10-11 Retroviral vectors carrying senescent cell derived inhibitors 1 (sdi-1) or antisense sdi-1 nucleotide sequences

Publications (1)

Publication Number Publication Date
DK0859854T3 true DK0859854T3 (da) 2002-08-19

Family

ID=8101648

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96934660T DK0859854T3 (da) 1995-10-13 1996-10-11 Retrovirale vektorer bærende aldrende celle-afledte inhibitorer 1 (SDI-1) eller antisense SDI-1 nukleotidsekvenser

Country Status (7)

Country Link
EP (1) EP0859854B1 (da)
AT (1) ATE217023T1 (da)
AU (1) AU7291696A (da)
DE (1) DE69621035T2 (da)
DK (1) DK0859854T3 (da)
ES (1) ES2176500T3 (da)
WO (1) WO1997013867A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6139817A (en) * 1996-10-15 2000-10-31 Smithkline Beecham Corporation Method for determining gene essentiality in a pathogen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302706A (en) * 1991-12-16 1994-04-12 Baylor College Of Medicine Senescent cell derived inhibitors of DNA synthesis
WO1994029437A1 (en) * 1993-06-07 1994-12-22 University Of Medicine & Dentistry Of New Jersey Highly-efficient, self-inactivating, recombination-free, u3-free retroviral vectors
JP3822232B2 (ja) * 1993-08-30 2006-09-13 ベイラー・カレッジ・オブ・メディシン 老化細胞由来ｄｎａ合成阻害因子
WO1995013375A1 (en) * 1993-11-10 1995-05-18 The Johns Hopkins University Tumor suppressor waf1
ATE200517T1 (de) * 1994-09-02 2001-04-15 Gsf Forschungszentrum Umwelt Nicht selbstinaktivierende retrovirale vektoren mit gezielter expression
US5863904A (en) * 1995-09-26 1999-01-26 The University Of Michigan Methods for treating cancers and restenosis with P21

Also Published As

Publication number Publication date
DE69621035D1 (de) 2002-06-06
WO1997013867A1 (en) 1997-04-17
EP0859854B1 (en) 2002-05-02
AU7291696A (en) 1997-04-30
EP0859854A1 (en) 1998-08-26
ES2176500T3 (es) 2002-12-01
ATE217023T1 (de) 2002-05-15
DE69621035T2 (de) 2003-01-02

Similar Documents

Publication Publication Date Title
DE69434663D1 (de) Nukleotid-sequenzen zur kontrolle der exprimierung von dns-sequenzen in einem zellulärem wirt
SG141233A1 (en) Control of gene expression
DE69819167D1 (de) Modifizierter, das dorsalgewebe beeinflussender faktor
PT101297A (pt) Factores mitogenicos gliais, sua preparacao e utilizacao
DK198883D0 (da) Fremgangsmade til fremstilling af menneskevaevs-plasminogenaktivator, dna-sekvens der koder for denne aktivator, replicerbar udtrykkelsesvektor for dna-sekvensen og microorganisme eller cellekultur transformeret med udtrykkelsesvektoren
ATE440863T1 (de) Chemokine peptide, varianten, derivate und analoge. ihre verwendung in methode für die hemmung oder erhíhung von einer entzündungsreaktion
ATE355370T1 (de) Starker homologer promotor aus hamster
ATE310812T1 (de) Derivate von zinkfingerproteinen und methoden
DE69504808T3 (de) Corticotropin freisetzende rezeptoren des faktor 2
ES2152313T3 (es) Gen grb-3-3, sus variantes y sus utilizaciones.
ATE534742T1 (de) Polypeptide und nukleinsäuren von phorphorymonas gingivalis
ATE435293T1 (de) Invertierte terminale repeats von aav, die für die transkription aktiviert sind, zur verwendung in rekombinanten aav-vektoren
DK0859854T3 (da) Retrovirale vektorer bærende aldrende celle-afledte inhibitorer 1 (SDI-1) eller antisense SDI-1 nukleotidsekvenser
DK0643719T3 (da) Nukleinsyresekvenser, som koder for eller er komplementære til nukleinsyresekvenser, som koder for interleukin 9-receptor
NO973679L (no) Eukaryotisk initieringsfaktor 5A (eIF-5A) mutanter
ATE89005T1 (de) Rekombinantes vektorsystem fuer metalloproteinase- inhibitorsequenz und dessen verwendung und herstellung nach dem rekombinant-dns-verfahren.
DK0665890T3 (da) Forøget produktion af udskilte proteiner med rekombinante eukaryotiske celler
DE69526087D1 (de) Or-1, ein wais-rezeptor der nuklearen rezeptoren familie
DE69535024D1 (de) Verpackungszellinie zur transkomplementierung von defektiven retroviren-vektoren