DK0752838T3 - Stabile suppositorieformuleringer af delta-9-THC (tetrahydrocannabinol) - Google Patents

Stabile suppositorieformuleringer af delta-9-THC (tetrahydrocannabinol)

Info

Publication number
DK0752838T3
DK0752838T3 DK94917418T DK94917418T DK0752838T3 DK 0752838 T3 DK0752838 T3 DK 0752838T3 DK 94917418 T DK94917418 T DK 94917418T DK 94917418 T DK94917418 T DK 94917418T DK 0752838 T3 DK0752838 T3 DK 0752838T3
Authority
DK
Denmark
Prior art keywords
delta
thc
tetrahydrocannabinol
suppository formulations
stable suppository
Prior art date
Application number
DK94917418T
Other languages
Danish (da)
English (en)
Inventor
Mahmoud A Elsohly
Original Assignee
Univ Mississippi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Mississippi filed Critical Univ Mississippi
Application granted granted Critical
Publication of DK0752838T3 publication Critical patent/DK0752838T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/15Suppositories

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK94917418T 1993-05-21 1994-05-17 Stabile suppositorieformuleringer af delta-9-THC (tetrahydrocannabinol) DK0752838T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/065,117 US5389375A (en) 1993-05-21 1993-05-21 Stable suppository formulations effecting bioavailability of Δ9 -thc
PCT/US1994/005512 WO1994027533A1 (en) 1993-05-21 1994-05-17 Stable suppository formulations effecting biovailability of δ9-thc

Publications (1)

Publication Number Publication Date
DK0752838T3 true DK0752838T3 (da) 2003-08-11

Family

ID=22060436

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94917418T DK0752838T3 (da) 1993-05-21 1994-05-17 Stabile suppositorieformuleringer af delta-9-THC (tetrahydrocannabinol)

Country Status (11)

Country Link
US (2) US5389375A (de)
EP (1) EP0752838B1 (de)
JP (1) JPH08510741A (de)
KR (1) KR100354403B1 (de)
AT (1) ATE237336T1 (de)
CA (1) CA2163363C (de)
DE (1) DE69432527T2 (de)
DK (1) DK0752838T3 (de)
MX (1) MX9403799A (de)
PL (1) PL175113B1 (de)
WO (1) WO1994027533A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6132762A (en) * 1997-05-05 2000-10-17 Cristobal; Walter Transcutaneous application of marijuana
US5847128A (en) * 1998-05-29 1998-12-08 Virginia Commonwealth University Water soluble derivatives of cannabinoids
US6008383A (en) * 1998-10-26 1999-12-28 University Of Mississippi Method of preparing delta-9-tetrahydrocannabinol esters
AU3697200A (en) 1999-02-04 2000-08-25 New Millennium Pharmaceutical Research, Inc. Method for enhancement of delivery of thc by the administration of its prodrugs via the nasal route
BR0009200A (pt) 1999-03-22 2001-12-26 Immugen Pharmaceuticals Inc Compostos e composições para o tratamento dedoenças associada com disfunção imune
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US6747058B1 (en) 1999-08-20 2004-06-08 Unimed Pharmaceuticals, Inc. Stable composition for inhalation therapy comprising delta-9-tetrahydrocannabinol and semiaqueous solvent therefor
US7648696B2 (en) * 1999-08-20 2010-01-19 Unimed Pharmaceuticals, Llc Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent
US20020137802A1 (en) * 2000-09-28 2002-09-26 Travis Craig R. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
AU2002213429A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
EP1321159A1 (de) * 2001-12-21 2003-06-25 CHIESI FARMACEUTICI S.p.A. Betätigungsvorrichtung für Druckdosierinhalator mit lasergebohrten Löchern
WO2003080043A1 (en) * 2002-03-18 2003-10-02 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
CA2573859A1 (en) * 2004-07-19 2006-01-26 Cilag Ltd. Method for obtaining pure tetrahydrocannabinol
TWI369203B (en) 2004-11-22 2012-08-01 Euro Celtique Sa Methods for purifying trans-(-)-△9-tetrahydrocannabinol and trans-(+)-△9-tetrahydrocannabinol
MX2007007038A (es) * 2004-12-09 2008-03-07 Insys Therapeutics Inc Formulacion de dronabinol en temperatura ambiente.
TWI366460B (en) * 2005-06-16 2012-06-21 Euro Celtique Sa Cannabinoid active pharmaceutical ingredient for improved dosage forms
CA2623723A1 (en) * 2005-09-29 2007-04-12 Amr Technology, Inc. Process for production of delta-9-tetrahydrocannabinol
WO2008019146A2 (en) * 2006-08-04 2008-02-14 Insys Therapeutics Inc. Aqueous dronabinol formulations
WO2008139263A2 (en) * 2006-11-30 2008-11-20 University Of Plymouth Methods for slowing the progression of multiple sclerosis
US20080181942A1 (en) * 2006-11-30 2008-07-31 University Of Plymouth Delta-9-THC compositions and methods for treating symptoms associated with multiple sclerosis
US8436051B2 (en) * 2007-06-08 2013-05-07 Aptalis Pharma Canada Inc. Mesalamine suppository
US8217083B2 (en) * 2007-06-08 2012-07-10 Aptalis Pharma Canada Inc. Mesalamine suppository
US7541384B2 (en) 2007-06-08 2009-06-02 Axcan Pharma Inc. Mesalamine suppository
JP2010535238A (ja) * 2007-07-30 2010-11-18 オールトランツ インコーポレイティド カンナビジオールのプロドラッグ、カンナビジオールのプロドラッグを含む組成物及びその使用方法
US20090181080A1 (en) * 2007-08-06 2009-07-16 Insys Therapeutics Inc. Oral cannabinnoid liquid formulations and methods of treatment
LT2963031T (lt) * 2007-11-30 2019-04-10 Zynerba Pharmaceuticals, Inc. Tetrahidrokanabinolio provaistai, provaistus apimančios tetrahidrokanabinolio kompozicijos ir jų panaudojimo būdai
JP5518418B2 (ja) * 2008-10-06 2014-06-11 第一三共ヘルスケア株式会社 坐薬製剤組成物
ES2622582T3 (es) * 2008-10-31 2017-07-06 University Of Mississippi Proceso para la preparación de ésteres de delta-9-THC-aminoácido
EP3528784B1 (de) * 2016-10-21 2023-08-02 APIRX Pharmaceutical USA, LLC Zäpfchen mit cannabinoiden
CA3029528C (en) 2017-09-08 2020-06-30 Zohar KOREN Compositions comprising a cannabinoid and spilanthol
CA3096547A1 (en) * 2018-04-13 2019-10-17 Urban Juve Provisions Inc. Cannabis root extract, method of manufacture, method of use
US10751299B2 (en) * 2018-09-04 2020-08-25 Babak Ghalili Cannabinoid and menthol compositions and methods
KR20220163384A (ko) 2020-03-04 2022-12-09 플레오파마, 엘.엘.씨. 칸나비스 사용 장애를 치료하고 칸나비노이드 금단을 완화하기 위한 방법 및 조성물
US12029718B2 (en) 2021-11-09 2024-07-09 Cct Sciences, Llc Process for production of essentially pure delta-9-tetrahydrocannabinol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3728360A (en) * 1971-08-31 1973-04-17 Little Inc A Ester derivatives of tetrahydrocannabinol
US4933363A (en) * 1988-08-16 1990-06-12 Elsohly Mahmoud A Method for effecting systemic delivery of delta-9-tetrahydrocannabinol

Also Published As

Publication number Publication date
AU6915194A (en) 1994-12-20
US5508037A (en) 1996-04-16
KR100354403B1 (ko) 2002-12-26
US5389375A (en) 1995-02-14
PL175113B1 (pl) 1998-11-30
EP0752838A1 (de) 1997-01-15
WO1994027533A1 (en) 1994-12-08
CA2163363A1 (en) 1994-12-08
CA2163363C (en) 2007-01-30
DE69432527D1 (de) 2003-05-22
JPH08510741A (ja) 1996-11-12
EP0752838B1 (de) 2003-04-16
PL311706A1 (en) 1996-03-04
AU689110B2 (en) 1998-03-26
ATE237336T1 (de) 2003-05-15
EP0752838A4 (de) 1996-05-30
MX9403799A (es) 1997-02-28
DE69432527T2 (de) 2004-04-08

Similar Documents

Publication Publication Date Title
DK0752838T3 (da) Stabile suppositorieformuleringer af delta-9-THC (tetrahydrocannabinol)
DK0656774T3 (da) Kosmetiske og dermatologiske lysbeskyttelsesformuleringer med et indhold af thioler og/eller thiolderivater
FI943749L (fi) Taksaanijohdannaisten fosfono-oksimetyylieetterit
ATE251108T1 (de) Compositionen auf basis von resveratrolderivaten
DK0781551T3 (da) Retinoid-formuleringer i porøse mikrosfærer til nedsat irritation og forbedret stabilitet
DK0650483T3 (da) (3R,4R)-Delta6-tetrahydrocannabinol-7-syrer
DK0513387T3 (da) Thiazolderivater som inhibitorer af aktivt oxygen
ATE56968T1 (de) Substituierte oxo-piperazinyl-triazine und uvlicht stabilisierte zubereitungen.
KR950700554A (ko) 집적된 광소자들의 정렬방법(alignment of integrated optical components)
DK0679154T3 (da) Ny krystallinsk form af en d-vitamininanalog
DK0426949T3 (da) Stabilisering af koncentrerede hydrogenperoxidopløsninger
DK1216692T3 (da) Anvendelse af alpha-CECH i kosmetiske præparater
MX9204563A (es) Nuevos derivados de la (2-alquil-3-piridil)-metilpiperazina y composicion farmaceutica que los comprende.
FI924478A0 (fi) 24-oxa-derivat i vitamin d-serien
FI945732A0 (fi) Vaahtoa hillitsevä koostumus, joka sisältää silikonia ja piidioksidia
PT99503A (pt) Processo para a preparacao de novos derivados da n-benzoil-prolina e de composicoes farmaceuticas que os contem
ES2052897T3 (es) Nucleosidos didesoxidideshidrocarbociclicos.
DE69409758D1 (de) Herstellung von Alkyl-Tert-Alkylethern
BR9811152A (pt) Composição que compreende própolis e pelo menos um óleo essencial e utilização da mesma
FI962235L (fi) Uudet bentseenisulfonyyli-imiinijohdannaiset IL-1:n toiminnan inhibiittoreina
DE59606190D1 (de) Stabile festformulierungen von cyclohexenonoximether-herbiziden
MX9205183A (es) Composiciones mejoradas de hidrogeles polimericos que contienen silicona
UY24915A1 (es) Derivados de benzoxazindiona, aplicación de los mismos y medicamentos que los contienen
DK0959175T3 (da) Sammensætninger omfattende formamidinsulfinsyre
FI962019A0 (fi) Pyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina aineina