DK0735047T3 - Sterolepoxider til cancerbehandling - Google Patents
Sterolepoxider til cancerbehandlingInfo
- Publication number
- DK0735047T3 DK0735047T3 DK95902957T DK95902957T DK0735047T3 DK 0735047 T3 DK0735047 T3 DK 0735047T3 DK 95902957 T DK95902957 T DK 95902957T DK 95902957 T DK95902957 T DK 95902957T DK 0735047 T3 DK0735047 T3 DK 0735047T3
- Authority
- DK
- Denmark
- Prior art keywords
- group
- carbon atoms
- hydroxyl group
- hydroxyl
- sterol
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 229930182558 Sterol Natural products 0.000 title 1
- -1 Sterol epoxides Chemical class 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 235000003702 sterols Nutrition 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
- C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP31524693 | 1993-12-15 | ||
| PCT/JP1994/002102 WO1995016699A1 (fr) | 1993-12-15 | 1994-12-14 | Derive de steroide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0735047T3 true DK0735047T3 (da) | 1999-07-26 |
Family
ID=18063133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95902957T DK0735047T3 (da) | 1993-12-15 | 1994-12-14 | Sterolepoxider til cancerbehandling |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5712263A (da) |
| EP (1) | EP0735047B1 (da) |
| AT (1) | ATE173271T1 (da) |
| AU (1) | AU679302B2 (da) |
| CA (1) | CA2178900A1 (da) |
| DE (1) | DE69414602T2 (da) |
| DK (1) | DK0735047T3 (da) |
| ES (1) | ES2124995T3 (da) |
| WO (1) | WO1995016699A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2330611A1 (en) | 1998-05-22 | 1999-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional molecules and therapies based thereon |
| DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
| SI1889198T1 (sl) | 2005-04-28 | 2015-02-27 | Proteus Digital Health, Inc. | Farma-informacijski sistem |
| WO2007035716A2 (en) | 2005-09-16 | 2007-03-29 | Raptor Pharmaceutical Inc. | Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof |
| WO2010095940A2 (en) | 2009-02-20 | 2010-08-26 | To-Bbb Holding B.V. | Glutathione-based drug delivery system |
| NZ596876A (en) | 2009-05-06 | 2014-01-31 | Lab Skin Care Inc | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5122521A (en) * | 1990-07-17 | 1992-06-16 | Taisho Pharmaceutical Co., Ltd. | Sterol compound |
-
1994
- 1994-12-14 EP EP95902957A patent/EP0735047B1/en not_active Expired - Lifetime
- 1994-12-14 CA CA002178900A patent/CA2178900A1/en not_active Abandoned
- 1994-12-14 DK DK95902957T patent/DK0735047T3/da active
- 1994-12-14 AU AU12003/95A patent/AU679302B2/en not_active Ceased
- 1994-12-14 WO PCT/JP1994/002102 patent/WO1995016699A1/ja active IP Right Grant
- 1994-12-14 AT AT95902957T patent/ATE173271T1/de not_active IP Right Cessation
- 1994-12-14 ES ES95902957T patent/ES2124995T3/es not_active Expired - Lifetime
- 1994-12-14 DE DE69414602T patent/DE69414602T2/de not_active Expired - Fee Related
-
1996
- 1996-06-14 US US08/663,929 patent/US5712263A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0735047A1 (en) | 1996-10-02 |
| AU679302B2 (en) | 1997-06-26 |
| EP0735047A4 (en) | 1996-11-27 |
| CA2178900A1 (en) | 1995-06-22 |
| DE69414602T2 (de) | 1999-04-08 |
| AU1200395A (en) | 1995-07-03 |
| US5712263A (en) | 1998-01-27 |
| ATE173271T1 (de) | 1998-11-15 |
| DE69414602D1 (de) | 1998-12-17 |
| WO1995016699A1 (fr) | 1995-06-22 |
| EP0735047B1 (en) | 1998-11-11 |
| ES2124995T3 (es) | 1999-02-16 |
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