DK0698093T3 - Von Hippel-Lindau-(VHL)-sygdomsgen og tilsvarende cDNA og metoder til påvisning af bærere af VHL-sygdomsgenet - Google Patents

Von Hippel-Lindau-(VHL)-sygdomsgen og tilsvarende cDNA og metoder til påvisning af bærere af VHL-sygdomsgenet

Info

Publication number
DK0698093T3
DK0698093T3 DK94916774T DK94916774T DK0698093T3 DK 0698093 T3 DK0698093 T3 DK 0698093T3 DK 94916774 T DK94916774 T DK 94916774T DK 94916774 T DK94916774 T DK 94916774T DK 0698093 T3 DK0698093 T3 DK 0698093T3
Authority
DK
Denmark
Prior art keywords
vhl
disease gene
lindau
methods
corresponding cdna
Prior art date
Application number
DK94916774T
Other languages
Danish (da)
English (en)
Inventor
Michael I Lerman
Farida Latif
Berton Zbar
Marston Linehan
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of DK0698093T3 publication Critical patent/DK0698093T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
DK94916774T 1993-05-14 1994-05-12 Von Hippel-Lindau-(VHL)-sygdomsgen og tilsvarende cDNA og metoder til påvisning af bærere af VHL-sygdomsgenet DK0698093T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/061,889 US5654138A (en) 1993-05-14 1993-05-14 Von hippel-lindau (VHL) disease gene and corresponding cDNA and methods for detecting carriers of the VHL disease gene
PCT/US1994/005378 WO1994026894A1 (fr) 1993-05-14 1994-05-12 GENE DE LA MALADIE DE VON HIPPEL-LINDAU (VHL) ET ADNc CORRESPONDANT, ET PROCEDES DE DETECTION DE PORTEURS DU GENE DE LA MALADIE DE VHL

Publications (1)

Publication Number Publication Date
DK0698093T3 true DK0698093T3 (da) 1999-11-29

Family

ID=22038796

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94916774T DK0698093T3 (da) 1993-05-14 1994-05-12 Von Hippel-Lindau-(VHL)-sygdomsgen og tilsvarende cDNA og metoder til påvisning af bærere af VHL-sygdomsgenet

Country Status (11)

Country Link
US (2) US5654138A (fr)
EP (1) EP0698093B1 (fr)
JP (1) JP3650397B2 (fr)
AT (1) ATE182622T1 (fr)
AU (1) AU696234B2 (fr)
CA (1) CA2162928A1 (fr)
DE (1) DE69419748T2 (fr)
DK (1) DK0698093T3 (fr)
ES (1) ES2135581T3 (fr)
GR (1) GR3030876T3 (fr)
WO (1) WO1994026894A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6312890B1 (en) * 1993-05-14 2001-11-06 The United States Of America As Represented By The Department Of Health And Human Services Partial intron sequence of von hippel-lindau (VHL) disease gene and its use in diagnosis of disease
US6013436A (en) * 1994-07-08 2000-01-11 Visible Genetics, Inc. Compositions and methods for diagnosis of mutation in the von Hippel-Lindau tumor suppressor gene
US5958684A (en) * 1995-10-02 1999-09-28 Van Leeuwen; Frederik Willem Diagnosis of neurodegenerative disease
US5830657A (en) * 1996-05-01 1998-11-03 Visible Genetics Inc. Method for single-tube sequencing of nucleic acid polymers
US5789168A (en) * 1996-05-01 1998-08-04 Visible Genetics Inc. Method for amplification and sequencing of nucleic acid polymers
US5888736A (en) * 1995-12-22 1999-03-30 Visible Genetics, Inc. Method, compositions and kit for detection and identification of microorganisms
DE69709087T2 (de) * 1996-05-01 2002-04-25 Visible Genetics, Inc. Verfahren zum nachweis und zur identifizierung von mikroorganismen
US6413718B1 (en) 1996-05-01 2002-07-02 Visible Genetics Inc. Method for sequencing of nucleic acid polymers
US6083699A (en) * 1996-05-01 2000-07-04 Visible Genetics Inc. Method for bi-directional sequencing of nucleic acid polymers
US6214555B1 (en) 1996-05-01 2001-04-10 Visible Genetics Inc. Method compositions and kit for detection
AU7125401A (en) * 2000-05-19 2001-12-03 David J Marshall Materials and methods for detection of nucleic acids
CA2425747C (fr) 2000-10-14 2012-01-24 Eragen Biosciences, Inc. Systemes d'essai biologique sur support solide et procede permettant d'utiliser des bases non normalisees
US7222059B2 (en) 2001-11-15 2007-05-22 Siemens Medical Solutions Diagnostics Electrophoretic trace simulator
NZ520322A (en) * 2002-07-19 2005-04-29 Auckland Uniservices Ltd Tumor treating composition and methods
US20050208023A1 (en) * 2002-07-19 2005-09-22 Krissansen Geoffrey W Tumor treating composition and methods
WO2004061077A2 (fr) * 2002-12-24 2004-07-22 North Carolina State University Augmentation de la production de gametes dans le cadre d'une commutation genique
US7494467B2 (en) * 2004-04-16 2009-02-24 Ethicon Endo-Surgery, Inc. Medical system having multiple ultrasound transducers or an ultrasound transducer and an RF electrode
EP1866643A2 (fr) * 2005-03-17 2007-12-19 The Regents of the University of California Biomarqueur destine au traitement de la sensibilite a l'inhibiteur du mtor dans le cas du cancer du rein
WO2012166824A2 (fr) * 2011-05-31 2012-12-06 Oregon Health And Science University Procédés et trousses qui identifient des tumeurs sensibles à des inhibiteurs de src
EP2747552A1 (fr) * 2011-08-23 2014-07-02 University of South Florida Modèles de blessures et de lésions pulmonaires inductibles sur des souris
CN110066874A (zh) * 2019-04-26 2019-07-30 复旦大学附属华山医院 血管母细胞瘤分型诊断试剂盒

Also Published As

Publication number Publication date
EP0698093B1 (fr) 1999-07-28
WO1994026894A1 (fr) 1994-11-24
JP3650397B2 (ja) 2005-05-18
AU696234B2 (en) 1998-09-03
AU6833794A (en) 1994-12-12
US5759790A (en) 1998-06-02
CA2162928A1 (fr) 1994-11-24
ES2135581T3 (es) 1999-11-01
EP0698093A1 (fr) 1996-02-28
US5654138A (en) 1997-08-05
DE69419748T2 (de) 1999-12-09
JPH08511158A (ja) 1996-11-26
GR3030876T3 (en) 1999-11-30
ATE182622T1 (de) 1999-08-15
DE69419748D1 (de) 1999-09-02

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