DK0697881T3 - New pharmaceutical compositions for oral administration containing cyclosporin - Google Patents

New pharmaceutical compositions for oral administration containing cyclosporin

Info

Publication number
DK0697881T3
DK0697881T3 DK94915073T DK94915073T DK0697881T3 DK 0697881 T3 DK0697881 T3 DK 0697881T3 DK 94915073 T DK94915073 T DK 94915073T DK 94915073 T DK94915073 T DK 94915073T DK 0697881 T3 DK0697881 T3 DK 0697881T3
Authority
DK
Denmark
Prior art keywords
oral administration
pharmaceutical compositions
new pharmaceutical
administration containing
containing cyclosporin
Prior art date
Application number
DK94915073T
Other languages
Danish (da)
Inventor
Monika Fleck
Klaus Neuer
Hatto Walch
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25925049&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0697881(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE4412201A external-priority patent/DE4412201A1/en
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK0697881T3 publication Critical patent/DK0697881T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Transplantation (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

New cyclosporine-containing, oral administration pharmaceutical compositions are easy to produce and have a good bioavailability. Besides cyclosporine as active substance, these compositions contain an alkylene polyether or polyester, and may optionally contain an alkylen polyol, an alkylen glycol, a polyalkylene glycol, an alkyl diether or partial ether of a low molecular mono- or polyoxyalkane diol and/or a vegetable oil or its hydrogenated or hydrolysed product.
DK94915073T 1993-04-20 1994-04-20 New pharmaceutical compositions for oral administration containing cyclosporin DK0697881T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4312728 1993-04-20
DE4412201A DE4412201A1 (en) 1993-04-20 1994-04-08 New pharmaceutical preparations for oral administration containing cyclosporin
PCT/EP1994/001228 WO1994023733A1 (en) 1993-04-20 1994-04-20 New cyclosporine-containing pharmaceutical compositions for oral administration

Publications (1)

Publication Number Publication Date
DK0697881T3 true DK0697881T3 (en) 2002-10-07

Family

ID=25925049

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94915073T DK0697881T3 (en) 1993-04-20 1994-04-20 New pharmaceutical compositions for oral administration containing cyclosporin

Country Status (13)

Country Link
EP (1) EP0697881B2 (en)
JP (2) JP3862273B2 (en)
AT (1) ATE218878T1 (en)
CA (1) CA2161143A1 (en)
CZ (1) CZ291237B6 (en)
DK (1) DK0697881T3 (en)
ES (1) ES2178653T3 (en)
FI (1) FI116120B (en)
HU (1) HUT72738A (en)
NO (1) NO321076B1 (en)
PT (1) PT697881E (en)
SK (1) SK283442B6 (en)
WO (1) WO1994023733A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
DE19545043A1 (en) * 1995-12-02 1997-06-05 Scherer Gmbh R P Pharmaceutical preparations for oral use and process for their preparation
DE29824679U1 (en) * 1997-01-30 2002-03-28 Novartis Ag, Basel Pharmaceutical compositions
WO1998040094A1 (en) * 1997-03-12 1998-09-17 Abbott Laboratories Hydrophilic binary systems for the administration of cyclosporine
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
DE69842121D1 (en) 1997-12-10 2011-03-17 Cyclosporine Therapeutics Ltd OMEGA-3 FATTY ACID PHARMACEUTICAL COMPOSITIONS
US6207179B1 (en) 2000-05-18 2001-03-27 Phoenix Scientific, Inc. Parasiticidal formulation for animals and a method of making this formulation
NZ531944A (en) 2001-10-19 2006-03-31 Isotechnika Inc Synthesis of cyclosporin analogs
US6979672B2 (en) 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
US7682433B2 (en) 2007-05-11 2010-03-23 Canon Kabushiki Kaisha Ink set, ink jet recording method, ink cartridge, recording unit, and ink jet recording apparatus

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH641356A5 (en) * 1979-02-27 1984-02-29 Sandoz Ag Pharmaceutical compositions containing cyclosporin
GB8903804D0 (en) † 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
EP0365044A3 (en) * 1984-08-02 1990-08-22 Sandoz Ag Novel pharmaceutical use of (nva)2-cyclosporine
DE68900991D1 (en) † 1988-01-29 1992-04-23 Sankyo Co CYCLOSPORIN COMPOSITIONS.
KR0148748B1 (en) † 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 A multiphase cyclosporin composition
BE1003009A5 (en) † 1989-02-09 1991-10-22 Sandoz Sa NOVEL PHARMACEUTICAL COMPOSITIONS BASED ON CYCLOSPORINS.

Also Published As

Publication number Publication date
EP0697881B1 (en) 2002-06-12
JP2006206615A (en) 2006-08-10
FI116120B (en) 2005-09-30
NO954152L (en) 1995-10-18
ES2178653T3 (en) 2003-01-01
FI954986A (en) 1995-10-19
WO1994023733A1 (en) 1994-10-27
PT697881E (en) 2002-10-31
SK283442B6 (en) 2003-07-01
NO321076B1 (en) 2006-03-13
EP0697881A1 (en) 1996-02-28
HUT72738A (en) 1996-05-28
JPH08508984A (en) 1996-09-24
ATE218878T1 (en) 2002-06-15
CZ291237B6 (en) 2003-01-15
EP0697881B2 (en) 2009-05-06
SK129895A3 (en) 1997-02-05
HU9503019D0 (en) 1995-12-28
CZ272995A3 (en) 1996-02-14
FI954986A0 (en) 1995-10-19
CA2161143A1 (en) 1994-10-27
NO954152D0 (en) 1995-10-18
JP3862273B2 (en) 2006-12-27

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