DK0692026T3 - En human T-cellereceptor fra den G-proteinkoblede receptorfamilie - Google Patents
En human T-cellereceptor fra den G-proteinkoblede receptorfamilieInfo
- Publication number
- DK0692026T3 DK0692026T3 DK94906667T DK94906667T DK0692026T3 DK 0692026 T3 DK0692026 T3 DK 0692026T3 DK 94906667 T DK94906667 T DK 94906667T DK 94906667 T DK94906667 T DK 94906667T DK 0692026 T3 DK0692026 T3 DK 0692026T3
- Authority
- DK
- Denmark
- Prior art keywords
- human
- receptor
- cell receptor
- protein
- nucleotide sequences
- Prior art date
Links
- 108091008874 T cell receptors Proteins 0.000 title abstract 3
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 title abstract 3
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 title 1
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 3
- 108020004511 Recombinant DNA Proteins 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0331—Animal model for proliferative diseases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0381—Animal model for diseases of the hematopoietic system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4653193A | 1993-04-09 | 1993-04-09 | |
| PCT/US1994/000598 WO1994024282A1 (en) | 1993-04-09 | 1994-01-28 | A human t-cell receptor of the g-protein coupled receptor family |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0692026T3 true DK0692026T3 (da) | 1999-09-27 |
Family
ID=21943934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94906667T DK0692026T3 (da) | 1993-04-09 | 1994-01-28 | En human T-cellereceptor fra den G-proteinkoblede receptorfamilie |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0692026B1 (da) |
| JP (1) | JPH08506246A (da) |
| AT (1) | ATE177783T1 (da) |
| CA (1) | CA2159813A1 (da) |
| DE (1) | DE69417223T2 (da) |
| DK (1) | DK0692026T3 (da) |
| ES (1) | ES2129120T3 (da) |
| GR (1) | GR3030152T3 (da) |
| WO (1) | WO1994024282A1 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5998196A (en) * | 1995-05-11 | 1996-11-29 | Karo Bio Ab | Transgenic animals having a defective thyroid hormone recept or beta gene |
| US5939320A (en) * | 1996-05-20 | 1999-08-17 | New York University | G-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof |
| US6258527B1 (en) | 1996-05-20 | 2001-07-10 | The Aaron Diamond Aids Research Center | Methods of identifying g-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof |
| US6057102A (en) * | 1996-08-08 | 2000-05-02 | The Aaron Diamond Aids Research Center | HIV coreceptor mutants |
| US6140064A (en) | 1996-09-10 | 2000-10-31 | Theodor-Kocher Institute | Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3 |
| RU2121718C1 (ru) | 1998-02-19 | 1998-11-10 | Яков Шоел-Берович Ровнер | Портативная музыкальная система для караоке и картридж для нее |
| WO2003000893A2 (en) * | 2001-06-26 | 2003-01-03 | Decode Genetics Ehf. | Nucleic acids encoding g protein-coupled receptors |
| WO2006036445A2 (en) | 2004-09-24 | 2006-04-06 | Trustees Of Dartmouth College | Chimeric nk receptor and methods for treating cancer |
| US9273283B2 (en) | 2009-10-29 | 2016-03-01 | The Trustees Of Dartmouth College | Method of producing T cell receptor-deficient T cells expressing a chimeric receptor |
| WO2011059836A2 (en) | 2009-10-29 | 2011-05-19 | Trustees Of Dartmouth College | T cell receptor-deficient t cell compositions |
| US9833476B2 (en) | 2011-08-31 | 2017-12-05 | The Trustees Of Dartmouth College | NKP30 receptor targeted therapeutics |
| JP6389166B2 (ja) | 2012-05-07 | 2018-09-12 | トラスティーズ・オブ・ダートマス・カレッジ | 抗ｂ７−ｈ６抗体、融合タンパク質、及びこれらを使用する方法 |
-
1994
- 1994-01-28 EP EP94906667A patent/EP0692026B1/en not_active Expired - Lifetime
- 1994-01-28 JP JP6523114A patent/JPH08506246A/ja active Pending
- 1994-01-28 DK DK94906667T patent/DK0692026T3/da active
- 1994-01-28 CA CA002159813A patent/CA2159813A1/en not_active Abandoned
- 1994-01-28 DE DE69417223T patent/DE69417223T2/de not_active Expired - Fee Related
- 1994-01-28 WO PCT/US1994/000598 patent/WO1994024282A1/en active IP Right Grant
- 1994-01-28 ES ES94906667T patent/ES2129120T3/es not_active Expired - Lifetime
- 1994-01-28 AT AT94906667T patent/ATE177783T1/de not_active IP Right Cessation
-
1999
- 1999-05-06 GR GR990401240T patent/GR3030152T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69417223T2 (de) | 1999-07-08 |
| CA2159813A1 (en) | 1994-10-27 |
| ATE177783T1 (de) | 1999-04-15 |
| EP0692026A1 (en) | 1996-01-17 |
| EP0692026B1 (en) | 1999-03-17 |
| ES2129120T3 (es) | 1999-06-01 |
| WO1994024282A1 (en) | 1994-10-27 |
| GR3030152T3 (en) | 1999-08-31 |
| DE69417223D1 (de) | 1999-04-22 |
| JPH08506246A (ja) | 1996-07-09 |
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