DK0678337T3 - apparatus - Google Patents

apparatus

Info

Publication number
DK0678337T3
DK0678337T3 DK95104175T DK95104175T DK0678337T3 DK 0678337 T3 DK0678337 T3 DK 0678337T3 DK 95104175 T DK95104175 T DK 95104175T DK 95104175 T DK95104175 T DK 95104175T DK 0678337 T3 DK0678337 T3 DK 0678337T3
Authority
DK
Denmark
Prior art keywords
eye
stream
formulation
electric charge
droplets
Prior art date
Application number
DK95104175T
Other languages
Danish (da)
Inventor
Raymond Charles Rowe
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK0678337T3 publication Critical patent/DK0678337T3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Bipolar Transistors (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Regulation And Control Of Combustion (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A method of administering to the eye a liquid ophthalmic formulation, comprising an ophthalmologically acceptable liquid and optionally containing an ophthalmologically-active substance, characterized in that the formulation has a viscosity in the range 10<-><3> to 1.0Pa.s and a resistivity lower than 10<4>ohm.cm, and that a jet of the formulation is ejected towards the eye, from a spray nozzle (12) situated adjacent to a piezoelectric or electromagnetic transducer (7), to form a stream of uniformly-sized, equally spaced, uncharged droplets, the stream of uncharged droplets is subsequently directed past a charging electrode (13) to induce an electric charge on each droplet in the stream, and the charged droplets discharge their electric charge by earthing on contact with the eye; and spraying apparatus suitable for use in that method. <IMAGE>
DK95104175T 1994-03-25 1995-03-22 apparatus DK0678337T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9405952A GB9405952D0 (en) 1994-03-25 1994-03-25 Aqueous ophthalmic sprays

Publications (1)

Publication Number Publication Date
DK0678337T3 true DK0678337T3 (en) 2002-04-15

Family

ID=10752506

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95104175T DK0678337T3 (en) 1994-03-25 1995-03-22 apparatus

Country Status (13)

Country Link
US (1) US5630793A (en)
EP (1) EP0678337B1 (en)
JP (2) JP3712438B2 (en)
AT (1) ATE212253T1 (en)
AU (1) AU693871B2 (en)
DE (1) DE69525095T2 (en)
DK (1) DK0678337T3 (en)
ES (1) ES2171172T3 (en)
GB (1) GB9405952D0 (en)
NZ (1) NZ282445A (en)
PT (1) PT678337E (en)
WO (1) WO1995026236A1 (en)
ZA (1) ZA951970B (en)

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US5807357A (en) * 1997-08-19 1998-09-15 Kang; Meng-Che Compact nebulizer for treating the eyes
IL122016A (en) * 1997-10-22 2001-09-13 Tav Tech Ltd Apparatus for dermal abrasion
US6159188A (en) * 1998-01-14 2000-12-12 Robert L. Rogers Apparatus and method for delivery of micro and submicro quantities of materials
US5997518A (en) * 1998-01-14 1999-12-07 Laibovitz; Robert A. Apparatus and method for delivery of small volumes of liquid
WO2000010640A1 (en) * 1998-08-19 2000-03-02 Gal-Ion Blaze Ltd. Method and device for topical administration of substances
US6378780B1 (en) 1999-02-09 2002-04-30 S. C. Johnson & Son, Inc. Delivery system for dispensing volatiles
US6382204B1 (en) 1999-10-14 2002-05-07 Becton Dickinson And Company Drug delivery system including holder and drug container
US6547770B2 (en) * 2000-04-14 2003-04-15 Aiolos Systems Aktiebolag (Ab) Ophthalmic dispensing device
US6482863B2 (en) 2000-12-15 2002-11-19 S. C. Johnson & Son, Inc. Insect repellant formulation deliverable by piezoelectric device
WO2002072169A2 (en) * 2001-03-09 2002-09-19 Antares Pharma, Inc. Ocular drug delivery nebulizer
US6811805B2 (en) * 2001-05-30 2004-11-02 Novatis Ag Method for applying a coating
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US20050261641A1 (en) * 2002-09-26 2005-11-24 Warchol Mark P Method for ophthalmic administration of medicament
US7201732B2 (en) * 2003-04-10 2007-04-10 Hewlett-Packard Development Company, L.P. Dispensing method and device for delivering material to an eye
US8012136B2 (en) 2003-05-20 2011-09-06 Optimyst Systems, Inc. Ophthalmic fluid delivery device and method of operation
US7883031B2 (en) 2003-05-20 2011-02-08 James F. Collins, Jr. Ophthalmic drug delivery system
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DE102004031261B4 (en) * 2004-06-29 2006-08-24 Franz-Josef Ebbing Eye dropper Help
DE102004048503A1 (en) * 2004-10-05 2006-04-13 Thilo Schleip Contact lens wetting device for human eye, has sprayers which apply solution to contact lens in eye, for wetting lens, where spraying output of sprayers are adjusted with respect to delivered volume of absorbency of eye
WO2006082588A2 (en) * 2005-02-07 2006-08-10 Pharmalight Inc. Method and device for ophthalmic administration of active pharmaceutical ingredients
US8056557B2 (en) 2005-03-09 2011-11-15 Ric Investments, Llc Nebulizing drug delivery device with barrier
US7814901B2 (en) 2005-03-09 2010-10-19 Ric Investments, Llc Nebulizing drug delivery device with increased flow rate
US7631643B2 (en) 2005-03-09 2009-12-15 Ric Investments, Llc Nebulizing drug delivery device with interlock detection and temperature protection
US7721729B2 (en) 2005-03-09 2010-05-25 Ric Investments, Llc Nebulizing drug delivery device for ventilator
US9339836B2 (en) 2005-05-23 2016-05-17 Biosonic Australia Pty Ltd Ultrasonic atomization apparatus
US7947010B2 (en) * 2005-07-08 2011-05-24 Depuy Products, Inc. Composition and system for wound decontamination
WO2010078428A1 (en) * 2008-12-30 2010-07-08 Optimyst Systems, Inc. Ophthalmic fluid delivery system
US8960575B2 (en) * 2009-01-13 2015-02-24 Finishing Brands Holdings Inc. Electrostatic spray system and method
US8893990B2 (en) * 2010-02-26 2014-11-25 Finishing Brands Holdings Inc. Electrostatic spray system
EA201390122A1 (en) 2010-07-15 2014-05-30 Коринтиан Офтэлмик, Инк. DEVICE FOR THE GENERATION OF DROPS
JP2013531044A (en) 2010-07-15 2013-08-01 コリンシアン オフサルミック，インコーポレイティド Eye drop delivery
JP2013531548A (en) * 2010-07-15 2013-08-08 コリンシアン オフサルミック，インコーポレイティド Method and system for performing teletherapy and remote monitoring
US10154923B2 (en) 2010-07-15 2018-12-18 Eyenovia, Inc. Drop generating device
US8833679B2 (en) 2010-11-24 2014-09-16 Finishing Brands Holdings, Inc. Electrostatic spray system with grounding teeth
WO2013090468A1 (en) 2011-12-12 2013-06-20 Corinthian Ophthalmic, Inc. High modulus polymeric ejector mechanism, ejector device, and methods of use
JP6329130B2 (en) 2012-04-10 2018-05-30 アイノビア，インコーポレイティド Spray ejector mechanism, device that provides charge separation and controllable droplet charge, and low dose eye drops
CN109011046B (en) 2012-04-20 2021-10-01 艾诺维亚股份有限公司 Device for delivering a fluid to a target
US9463486B2 (en) 2012-05-14 2016-10-11 Eyenovia, Inc. Laminar flow droplet generator device and methods of use
MX2014013962A (en) 2012-05-15 2015-06-17 Eyenovia Inc Ejector devices, methods, drivers, and circuits therefor.
US9642742B2 (en) 2012-10-02 2017-05-09 Harold D. Mansfield Eye drop applicator and drop transfer method
WO2016115050A1 (en) 2015-01-12 2016-07-21 Lagunita Llc Micro-droplet delivery device and methods
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JP2021529598A (en) * 2018-07-03 2021-11-04 ケダリオン セラピューティックス，インコーポレイテッド Local intraocular delivery device and method using it
CN109140359B (en) * 2018-09-18 2021-12-10 深圳市伯乐照明有限公司 LED street lamp for municipal construction
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US11679028B2 (en) 2019-03-06 2023-06-20 Novartis Ag Multi-dose ocular fluid delivery system
US11938057B2 (en) 2020-04-17 2024-03-26 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
US12090087B2 (en) 2020-04-17 2024-09-17 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system having a collapsible liquid reservoir
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Also Published As

Publication number Publication date
ES2171172T3 (en) 2002-09-01
WO1995026236A1 (en) 1995-10-05
AU693871B2 (en) 1998-07-09
JPH07265425A (en) 1995-10-17
GB9405952D0 (en) 1994-05-11
JP2005254026A (en) 2005-09-22
EP0678337B1 (en) 2002-01-23
EP0678337A1 (en) 1995-10-25
ZA951970B (en) 1995-09-26
JP3712438B2 (en) 2005-11-02
DE69525095T2 (en) 2002-12-19
AU1955295A (en) 1995-10-17
DE69525095D1 (en) 2002-03-14
PT678337E (en) 2002-06-28
JP3825039B2 (en) 2006-09-20
NZ282445A (en) 1998-04-27
US5630793A (en) 1997-05-20
ATE212253T1 (en) 2002-02-15

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