CA2182694A1 - Aqueous ophthalmic sprays - Google Patents

Aqueous ophthalmic sprays

Info

Publication number
CA2182694A1
CA2182694A1 CA002182694A CA2182694A CA2182694A1 CA 2182694 A1 CA2182694 A1 CA 2182694A1 CA 002182694 A CA002182694 A CA 002182694A CA 2182694 A CA2182694 A CA 2182694A CA 2182694 A1 CA2182694 A1 CA 2182694A1
Authority
CA
Canada
Prior art keywords
eye
stream
formulation
electric charge
droplets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002182694A
Other languages
French (fr)
Other versions
CA2182694C (en
Inventor
Raymond Charles Rowe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca UK Ltd
Original Assignee
Raymond Charles Rowe
Zeneca Limited
Syngenta Limited
Astrazeneca Uk Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9405952A external-priority patent/GB9405952D0/en
Application filed by Raymond Charles Rowe, Zeneca Limited, Syngenta Limited, Astrazeneca Uk Limited filed Critical Raymond Charles Rowe
Publication of CA2182694A1 publication Critical patent/CA2182694A1/en
Application granted granted Critical
Publication of CA2182694C publication Critical patent/CA2182694C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers

Landscapes

  • Medicinal Preparation (AREA)

Abstract

A method of administering to the eye a liquid ophthalmic formulation, comprising an ophthalmologically acceptable liquid and optionally containing an ophthalmologically-active substance, characterized in that the formulation has a viscosity in the range 10-3 to 1.0 Pa.s and a resistivity lower than 104 ohm.cm, and that a jet of the formulation is ejected towards the eye, from a spray nozzle (12) situated adjacent to a piezoelectric or electromagnetic transducer (7), to form a stream of uniformly-sized, equally spaced, uncharged droplets, the stream of uncharged droplets is subsequently directed past a charging electrode (13) to induce an electric charge on each droplet in the stream, and the charged droplets discharge their electric charge by earthing on contact with the eye; and spraying apparatus suitable for use in that method.
CA002182694A 1994-03-25 1995-03-23 Aqueous ophthalmic sprays Expired - Fee Related CA2182694C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9405952.4 1994-03-25
GB9405952A GB9405952D0 (en) 1994-03-25 1994-03-25 Aqueous ophthalmic sprays
PCT/GB1995/000643 WO1995026236A1 (en) 1994-03-25 1995-03-23 Aqueous ophthalmic sprays

Publications (2)

Publication Number Publication Date
CA2182694A1 true CA2182694A1 (en) 1995-10-05
CA2182694C CA2182694C (en) 2007-04-03

Family

ID=37951689

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002182694A Expired - Fee Related CA2182694C (en) 1994-03-25 1995-03-23 Aqueous ophthalmic sprays

Country Status (1)

Country Link
CA (1) CA2182694C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109674576A (en) * 2017-10-19 2019-04-26 深圳市启明医药科技有限公司 Fluid supply unit and fine liquid drop spray driving device, generating device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109674576A (en) * 2017-10-19 2019-04-26 深圳市启明医药科技有限公司 Fluid supply unit and fine liquid drop spray driving device, generating device
CN109674576B (en) * 2017-10-19 2024-02-27 深圳市启明医药科技有限公司 Fluid supply unit, micro-droplet ejection driving device, and generation device

Also Published As

Publication number Publication date
CA2182694C (en) 2007-04-03

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130325