DK0667164T3 - Use of hydrolytic enzymes to reduce or avoid the side effects of bleomycin - Google Patents

Use of hydrolytic enzymes to reduce or avoid the side effects of bleomycin

Info

Publication number
DK0667164T3
DK0667164T3 DK94102079T DK94102079T DK0667164T3 DK 0667164 T3 DK0667164 T3 DK 0667164T3 DK 94102079 T DK94102079 T DK 94102079T DK 94102079 T DK94102079 T DK 94102079T DK 0667164 T3 DK0667164 T3 DK 0667164T3
Authority
DK
Denmark
Prior art keywords
bleomycin
side effects
avoid
reduce
hydrolytic enzymes
Prior art date
Application number
DK94102079T
Other languages
Danish (da)
Inventor
Dr Ransberger Karl
W Dr Schedler Michael
Dr Stauder Gerhard
Original Assignee
Mucos Emulsions Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mucos Emulsions Gmbh filed Critical Mucos Emulsions Gmbh
Application granted granted Critical
Publication of DK0667164T3 publication Critical patent/DK0667164T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A61K38/166—Streptokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator

Abstract

The use of hydrolytic enzymes to prepare medicines for reducing or avoiding the side effects of bleomycin is new.
DK94102079T 1994-02-10 1994-02-10 Use of hydrolytic enzymes to reduce or avoid the side effects of bleomycin DK0667164T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94102079A EP0667164B1 (en) 1994-02-10 1994-02-10 Use of hydrolytic enzyme for reducing or preventing side effects of bleomycine

Publications (1)

Publication Number Publication Date
DK0667164T3 true DK0667164T3 (en) 2000-05-29

Family

ID=8215675

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94102079T DK0667164T3 (en) 1994-02-10 1994-02-10 Use of hydrolytic enzymes to reduce or avoid the side effects of bleomycin

Country Status (7)

Country Link
EP (1) EP0667164B1 (en)
AT (1) ATE188121T1 (en)
DE (1) DE59409038D1 (en)
DK (1) DK0667164T3 (en)
ES (1) ES2141776T3 (en)
GR (1) GR3032850T3 (en)
PT (1) PT667164E (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1951822C3 (en) * 1969-10-14 1980-12-11 Kowa Co., Ltd., Nagoya, Aichi (Japan) Pharmaceutical preparation for the treatment of cancer
FR2665363B1 (en) * 1990-07-31 1992-12-04 Cayla PHARMACEUTICAL COMPOSITION COMPRISING BLEOMYCIN (S) AND BLEOMYCIN-INACTIVE PROTEIN (S).

Also Published As

Publication number Publication date
DE59409038D1 (en) 2000-02-03
EP0667164A1 (en) 1995-08-16
ES2141776T3 (en) 2000-04-01
EP0667164B1 (en) 1999-12-29
PT667164E (en) 2000-04-28
GR3032850T3 (en) 2000-07-31
ATE188121T1 (en) 2000-01-15

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