DK0665853T3 - Multimere polyvalente antitrombotiske midler - Google Patents
Multimere polyvalente antitrombotiske midlerInfo
- Publication number
- DK0665853T3 DK0665853T3 DK93924287T DK93924287T DK0665853T3 DK 0665853 T3 DK0665853 T3 DK 0665853T3 DK 93924287 T DK93924287 T DK 93924287T DK 93924287 T DK93924287 T DK 93924287T DK 0665853 T3 DK0665853 T3 DK 0665853T3
- Authority
- DK
- Denmark
- Prior art keywords
- antithrombotic agents
- cyclic peptides
- including linear
- platelet
- specific binding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95546692A | 1992-10-02 | 1992-10-02 | |
PCT/US1993/009387 WO1994007918A1 (en) | 1992-10-02 | 1993-10-01 | Multimeric polyvalent antithrombotic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0665853T3 true DK0665853T3 (da) | 2002-11-04 |
Family
ID=25496861
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93924287T DK0665853T3 (da) | 1992-10-02 | 1993-10-01 | Multimere polyvalente antitrombotiske midler |
Country Status (11)
Country | Link |
---|---|
US (2) | US5977064A (da) |
EP (1) | EP0665853B1 (da) |
JP (1) | JPH08502261A (da) |
AT (1) | ATE222264T1 (da) |
AU (1) | AU696206B2 (da) |
CA (1) | CA2145847A1 (da) |
DE (1) | DE69332203T2 (da) |
DK (1) | DK0665853T3 (da) |
ES (1) | ES2182833T3 (da) |
WO (1) | WO1994007918A1 (da) |
ZA (1) | ZA937300B (da) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6019958A (en) * | 1991-02-08 | 2000-02-01 | Diatide, Inc. | Technetium-99m labeled peptides for imaging inflammation |
US5849261A (en) * | 1991-02-08 | 1998-12-15 | Diatide, Inc. | Radiolabeled vasoactive intestinal peptides for diagnosis and therapy |
US5830856A (en) * | 1991-02-08 | 1998-11-03 | Diatide, Inc. | Radiolabeled compounds for thrombus imaging |
AU709306B2 (en) * | 1992-04-30 | 1999-08-26 | Cis Bio International | Radiolabeled compounds for thrombus imaging |
US5508020A (en) * | 1992-06-05 | 1996-04-16 | Diatech, Inc. | Technetium-99M labeled peptides for imaging |
US5620675A (en) | 1992-06-23 | 1997-04-15 | Diatech, Inc. | Radioactive peptides |
JPH08502261A (ja) * | 1992-10-02 | 1996-03-12 | ダイアテク,インコーポレイテッド | 多重多価抗血栓症剤 |
US6051206A (en) * | 1994-06-03 | 2000-04-18 | Diatide, Inc | Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses |
US6254852B1 (en) | 1999-07-16 | 2001-07-03 | Dupont Pharmaceuticals Company | Porous inorganic targeted ultrasound contrast agents |
CZ2002343A3 (cs) | 1999-07-29 | 2002-08-14 | Epix Medical, Inc. | Cílená multimerní zobrazovací činidla s multilokální vazebnou schopností |
TWI221406B (en) * | 2001-07-30 | 2004-10-01 | Epix Medical Inc | Systems and methods for targeted magnetic resonance imaging of the vascular system |
AR047692A1 (es) * | 2003-07-10 | 2006-02-08 | Epix Medical Inc | Imagenes de blancos estacionarios |
US20080267882A1 (en) * | 2007-04-27 | 2008-10-30 | Stanford University | Imaging compounds, methods of making imaging compounds, methods of imaging, therapeutic compounds, methods of making therapeutic compounds, and methods of therapy |
CN102088991A (zh) | 2008-05-13 | 2011-06-08 | 堪萨斯大学 | 金属提取肽标签和相关方法 |
US20120076283A1 (en) | 2010-09-23 | 2012-03-29 | Ajmera Dinesh | Predictive Customer Service Environment |
US11080721B2 (en) | 2012-04-20 | 2021-08-03 | 7.ai, Inc. | Method and apparatus for an intuitive customer experience |
WO2013181461A2 (en) | 2012-06-01 | 2013-12-05 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
CN103665107B (zh) | 2012-09-05 | 2017-07-14 | 上海晟顺生物科技有限公司 | 同时具溶血栓、清除自由基和血栓靶向功能的新颖化合物及其制备方法和用途 |
US20220380478A1 (en) | 2019-07-01 | 2022-12-01 | Tonix Pharma Holdings Limited | Anti-cd154 antibodies and uses thereof |
EP4274587A1 (en) | 2021-01-06 | 2023-11-15 | Tonix Pharma Limited | Methods of inducing immune tolerance with modified anti-cd154 antibodies |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4614517A (en) * | 1982-08-04 | 1986-09-30 | La Jolla Cancer Research Foundation | Tetrapeptide |
US4792525A (en) * | 1982-08-04 | 1988-12-20 | La Jolla Cancer Research Foundation | Tetrapeptide |
US4578079A (en) * | 1982-08-04 | 1986-03-25 | La Jolla Cancer Research Foundation | Tetrapeptide |
EP0274868A1 (en) * | 1986-12-13 | 1988-07-20 | A.s. Clausen, Kaldager & Co. | Measuring apparatus |
US4843647A (en) * | 1987-08-31 | 1989-07-04 | Burlington Industries, Inc. | Cold weather system |
WO1989005150A1 (en) * | 1987-12-10 | 1989-06-15 | La Jolla Cancer Research Foundation | Conformationally stabilized cell adhesion peptides |
AU3569189A (en) * | 1988-04-29 | 1989-11-24 | New England Deaconess Hospital Corporation | Hybrid peptides and methods of their use |
CA2000666C (en) * | 1988-10-14 | 1996-07-09 | Jeffrey Lawrence Finnan | Method of making a free-flowing, spray-dried edible powder comprising an oil |
FR2639232A1 (fr) * | 1988-10-21 | 1990-05-25 | Sanofi Sa | Medicaments contenant une interleukine-2 glycosylee |
ES2084688T3 (es) * | 1988-12-20 | 1996-05-16 | Jolla Cancer Res Found | Conjugados de polipeptido-polimero para el tratamiento de heridas. |
US5196510A (en) * | 1988-12-29 | 1993-03-23 | Cytogen Corporation | Molecular recognition units |
US5384309A (en) * | 1989-07-17 | 1995-01-24 | Genentech, Inc. | Cyclized peptides and their use as platelet aggregation inhibitors |
EP0410537A1 (en) * | 1989-07-28 | 1991-01-30 | Merck & Co. Inc. | Fibrinogen receptor antagonists |
EP0410541A1 (en) * | 1989-07-28 | 1991-01-30 | Merck & Co. Inc. | Fibrinogen receptor antagonists |
CA2021951A1 (en) * | 1989-07-28 | 1991-01-29 | Ruth F. Nutt | Fibrinogen receptor antagonists |
CA2021952A1 (en) * | 1989-07-28 | 1991-01-29 | Ruth F. Nutt | Fibrinogen receptor antagonists |
DE3925962A1 (de) * | 1989-08-05 | 1991-02-07 | Thomson Brandt Gmbh | Videorecorder mit bandstandsanzeige |
FR2651077B1 (fr) * | 1989-08-18 | 1994-06-10 | Letourneur Gregoire | Dispositif de traitement d'echo notamment acoustique dans une ligne telephonique |
US5196404B1 (en) * | 1989-08-18 | 1996-09-10 | Biogen Inc | Inhibitors of thrombin |
US4952562A (en) * | 1989-09-29 | 1990-08-28 | Rorer Pharmaceutical Corporation | Anti-thrombotic peptides and pseudopeptides |
NZ235563A (en) * | 1989-10-13 | 1993-04-28 | Merck & Co Inc | Fibrinogen receptor antagonist and pharmaceutical composition |
NZ235564A (en) * | 1989-10-13 | 1993-10-26 | Merck & Co Inc | Fibrinogen receptor antagonist and pharmaceutical compositions |
AU6470590A (en) * | 1989-10-23 | 1991-04-26 | Smithkline Beecham Corporation | Cyclic anti-aggregatory peptides |
US5091542A (en) * | 1990-03-09 | 1992-02-25 | Hybritech Incorporated | Tris-maleimido compounds as intermediates in trifunctional antibody synthesis |
DK0527798T3 (da) * | 1990-04-06 | 1997-12-15 | Jolla Cancer Res Found | Fremgangsmåde og sammensætning til behandling af thrombose |
US5185433A (en) * | 1990-04-09 | 1993-02-09 | Centocor, Inc. | Cross-linking protein compositions having two or more identical binding sites |
US5298488A (en) * | 1990-10-26 | 1994-03-29 | Fuji Photo Film Co., Ltd. | CM-chitin derivatives and use thereof |
JP2745351B2 (ja) * | 1991-02-14 | 1998-04-28 | 富士写真フイルム株式会社 | ペプチド誘導体及びその用途 |
JPH06509551A (ja) * | 1991-04-05 | 1994-10-27 | ジェネンテク,インコーポレイテッド | Gp II↓bIII↓aに対する高い特異性を有する血小板凝集阻害剤 |
US5508020A (en) * | 1992-06-05 | 1996-04-16 | Diatech, Inc. | Technetium-99M labeled peptides for imaging |
US5338725A (en) * | 1992-06-30 | 1994-08-16 | The Research Foundation Of The State University Of New York | Anti-aggregatory agents for platelets |
JPH08502261A (ja) * | 1992-10-02 | 1996-03-12 | ダイアテク,インコーポレイテッド | 多重多価抗血栓症剤 |
AU7763194A (en) * | 1994-06-16 | 1996-01-04 | Nassif Haddad | Building block |
-
1993
- 1993-10-01 JP JP6509353A patent/JPH08502261A/ja active Pending
- 1993-10-01 ZA ZA937300A patent/ZA937300B/xx unknown
- 1993-10-01 ES ES93924287T patent/ES2182833T3/es not_active Expired - Lifetime
- 1993-10-01 CA CA002145847A patent/CA2145847A1/en not_active Abandoned
- 1993-10-01 AU AU54026/94A patent/AU696206B2/en not_active Ceased
- 1993-10-01 DK DK93924287T patent/DK0665853T3/da active
- 1993-10-01 EP EP93924287A patent/EP0665853B1/en not_active Expired - Lifetime
- 1993-10-01 WO PCT/US1993/009387 patent/WO1994007918A1/en active IP Right Grant
- 1993-10-01 AT AT93924287T patent/ATE222264T1/de not_active IP Right Cessation
- 1993-10-01 DE DE69332203T patent/DE69332203T2/de not_active Expired - Fee Related
-
1994
- 1994-12-22 US US08/361,864 patent/US5977064A/en not_active Expired - Fee Related
-
1995
- 1995-06-06 US US08/466,290 patent/US6150329A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2182833T3 (es) | 2003-03-16 |
EP0665853A1 (en) | 1995-08-09 |
DE69332203T2 (de) | 2003-05-28 |
AU696206B2 (en) | 1998-09-03 |
ATE222264T1 (de) | 2002-08-15 |
DE69332203D1 (de) | 2002-09-19 |
WO1994007918A1 (en) | 1994-04-14 |
JPH08502261A (ja) | 1996-03-12 |
US5977064A (en) | 1999-11-02 |
US6150329A (en) | 2000-11-21 |
CA2145847A1 (en) | 1994-04-14 |
ZA937300B (en) | 1995-03-30 |
AU5402694A (en) | 1994-04-26 |
EP0665853B1 (en) | 2002-08-14 |
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