DK0658557T3 - Eburnan-derivater, fremgangsmåde til fremstilling af sådanne derivater og farmaceutiske sammensætninger indeholdende disse - Google Patents

Eburnan-derivater, fremgangsmåde til fremstilling af sådanne derivater og farmaceutiske sammensætninger indeholdende disse

Info

Publication number
DK0658557T3
DK0658557T3 DK94402862T DK94402862T DK0658557T3 DK 0658557 T3 DK0658557 T3 DK 0658557T3 DK 94402862 T DK94402862 T DK 94402862T DK 94402862 T DK94402862 T DK 94402862T DK 0658557 T3 DK0658557 T3 DK 0658557T3
Authority
DK
Denmark
Prior art keywords
derivatives
preparing
pharmaceutical compositions
compositions containing
eburnan
Prior art date
Application number
DK94402862T
Other languages
English (en)
Inventor
Jean-Daniel Brion
Claude Thal
Luc Demuynck
Jean-Gilles Parmentier
Jean Lepagnol
Pierre Lestage
Jean-Fran Ois Pujol
Pascal Schmitt
Pierre Potier
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of DK0658557T3 publication Critical patent/DK0658557T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK94402862T 1993-12-14 1994-12-13 Eburnan-derivater, fremgangsmåde til fremstilling af sådanne derivater og farmaceutiske sammensætninger indeholdende disse DK0658557T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9314944A FR2713644B1 (fr) 1993-12-14 1993-12-14 Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
DK0658557T3 true DK0658557T3 (da) 1999-05-31

Family

ID=9453863

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94402862T DK0658557T3 (da) 1993-12-14 1994-12-13 Eburnan-derivater, fremgangsmåde til fremstilling af sådanne derivater og farmaceutiske sammensætninger indeholdende disse

Country Status (13)

Country Link
US (2) US5602131A (da)
EP (1) EP0658557B1 (da)
JP (1) JP2672269B2 (da)
AT (1) ATE170520T1 (da)
AU (1) AU679132B2 (da)
CA (1) CA2137889C (da)
CY (1) CY2160B1 (da)
DE (1) DE69412980T2 (da)
DK (1) DK0658557T3 (da)
ES (1) ES2123739T3 (da)
FR (1) FR2713644B1 (da)
NZ (1) NZ270132A (da)
ZA (1) ZA949973B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1315971A2 (en) * 2000-07-31 2003-06-04 The Regents of The University of California Model for alzheimer's disease and other neurodegenerative diseases
FR2888238B1 (fr) * 2005-07-07 2007-09-07 Servier Lab Nouveaux derives 1h-indole-pyridinecarboxamides et 1h-indole-piperidinecarboxamide, leur procede de preparation et les compositions pharceumatiques qui les contiennent.
FR2911142A1 (fr) * 2007-01-05 2008-07-11 Servier Lab Nouveaux derives aminopyrrolo[1,2-a]indole et aminopyridazino[1,6-a]indole,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2911141B1 (fr) * 2007-01-05 2009-02-20 Servier Lab Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2911143A1 (fr) * 2007-01-05 2008-07-11 Servier Lab Utilisation de composes neuroprotecteurs pour l'obtention de medicaments destines au traitement de maladies neurodegeneratives.
FR2926077A1 (fr) 2008-01-04 2009-07-10 Servier Lab Nouveaux derives d'1h-indol-1-yl uree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
EP3525788B1 (en) * 2016-10-11 2022-05-25 Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) Treatment of synucleinopathies

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3454583A (en) * 1965-07-19 1969-07-08 Us Health Education & Welfare Synthesis of vincamine
FR2081587B1 (da) * 1970-03-26 1973-04-06 Anvar
GB2009749B (en) * 1977-11-25 1982-04-28 Scras Indolo(1,3-a)quinolizidines
ZA786426B (en) * 1977-11-25 1979-10-31 Scras New indulo(2,3-a)quinolizidines,preparation and therapeutic use
US4283401A (en) * 1978-07-12 1981-08-11 Richter Gedeon Vegyeszeti Gyar Rt Process for the preparation of 11-bromo-vincaminic acid ester derivatives and their use in protecting animals against cerebral hypoxy
JPS5732281A (en) * 1980-08-06 1982-02-20 Sumitomo Chem Co Ltd Nitrogen-containing polycyclic compound and its preparation
HU182411B (en) * 1981-11-03 1984-01-30 Richter Gedeon Vegyeszet Process for preparing eburnamonine derivatives
JPS6127986A (ja) * 1984-07-18 1986-02-07 Sankyo Co Ltd 縮環複素環化合物
FR2614022B1 (fr) * 1987-04-15 1989-12-01 Roussel Uclaf Nouveaux derives 17-aza de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et ces compositions les renfermant
FR2623503B1 (da) * 1987-11-19 1991-04-05 Roussel Uclaf

Also Published As

Publication number Publication date
US5622957A (en) 1997-04-22
EP0658557A1 (fr) 1995-06-21
DE69412980T2 (de) 1999-05-12
JPH07215976A (ja) 1995-08-15
AU8038794A (en) 1995-02-23
FR2713644A1 (fr) 1995-06-16
CY2160B1 (en) 2002-08-23
ATE170520T1 (de) 1998-09-15
JP2672269B2 (ja) 1997-11-05
ES2123739T3 (es) 1999-01-16
ZA949973B (en) 1995-08-22
EP0658557B1 (fr) 1998-09-02
CA2137889C (fr) 2002-03-12
DE69412980D1 (de) 1998-10-08
US5602131A (en) 1997-02-11
AU679132B2 (en) 1997-06-19
NZ270132A (en) 1995-09-26
FR2713644B1 (fr) 1996-02-09
CA2137889A1 (fr) 1995-06-15

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