DK0637957T3 - Use of an Omega-3 Fatty Acid Emulsion to Prepare a Drug for Parenteral Treatment of Inflammatory Diseases - Google Patents

Use of an Omega-3 Fatty Acid Emulsion to Prepare a Drug for Parenteral Treatment of Inflammatory Diseases

Info

Publication number
DK0637957T3
DK0637957T3 DK93909844.8T DK93909844T DK0637957T3 DK 0637957 T3 DK0637957 T3 DK 0637957T3 DK 93909844 T DK93909844 T DK 93909844T DK 0637957 T3 DK0637957 T3 DK 0637957T3
Authority
DK
Denmark
Prior art keywords
omega
oils
fatty acids
inflammatory diseases
drug
Prior art date
Application number
DK93909844.8T
Other languages
Danish (da)
Inventor
David P Katz
Ewald Schlotzer
Peter Fuerst
Jeffrey Askanazi
Original Assignee
Fresenius Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Ag filed Critical Fresenius Ag
Application granted granted Critical
Publication of DK0637957T3 publication Critical patent/DK0637957T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

The object of the invention is the use of an emulsion containing one or more polyunsaturated, long-chained omega-3 fatty acids or their pharmaceutically acceptable esters or salts and the usual adjuvants or additives to produce a medicament to be parenterally administered for the treatment of inflammatory diseases, especially inflammatory lung diseases, inflammatory intestinal diseases and lupus erythematodes, especially mucoviscidosis and/or colitis ulcerosa. In the emulsions used in the invention, the omega-3 fatty acids, their pharmaceutically acceptable esters or salts are contained in pure form or as a component of oils like natural, prepared, semi-synthetic or synthetic oils, preferably fish oils. The preferred forms of such emulsions are those containing oils, preferably fish oils, glycerin, at least one emulsifier and water for injection purposes, in which the oils contain at least 20 wt % omega-3 fatty acids.
DK93909844.8T 1992-04-28 1993-04-27 Use of an Omega-3 Fatty Acid Emulsion to Prepare a Drug for Parenteral Treatment of Inflammatory Diseases DK0637957T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87524392A 1992-04-28 1992-04-28

Publications (1)

Publication Number Publication Date
DK0637957T3 true DK0637957T3 (en) 1997-08-18

Family

ID=25365445

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93909844.8T DK0637957T3 (en) 1992-04-28 1993-04-27 Use of an Omega-3 Fatty Acid Emulsion to Prepare a Drug for Parenteral Treatment of Inflammatory Diseases

Country Status (8)

Country Link
EP (1) EP0637957B1 (en)
JP (1) JP3559039B2 (en)
AT (1) ATE155684T1 (en)
DE (1) DE59306981D1 (en)
DK (1) DK0637957T3 (en)
ES (1) ES2107663T3 (en)
GR (1) GR3024526T3 (en)
WO (1) WO1993021912A1 (en)

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EP0754001B1 (en) * 1994-04-01 2002-01-23 Abbott Laboratories Nutritional product for treatment of ulcerative colitis and use thereof
US5952314A (en) 1994-04-01 1999-09-14 Demichele; Stephen Joseph Nutritional product for a person having ulcerative colitis
US5780451A (en) * 1994-04-01 1998-07-14 Abbott Laboratories Nutritional product for a person having ulcerative colitis
EP0689835A3 (en) * 1994-06-30 1996-04-17 Ajinomoto Kk Composition comprising a mixture of amino acids and at least one N-3 fatty acid
US6180671B1 (en) 1998-03-10 2001-01-30 Beth Israel Deaconess Medical Center, Inc. Methods for treating disorders in which docosahexaenoic acid (DHA) levels are affected
US6140374A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
US6191154B1 (en) * 1998-11-27 2001-02-20 Case Western Reserve University Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases
AU2001256334A1 (en) * 2000-05-05 2001-11-20 Fresenius Kabi Deutschland Gmbh Combination preparation consisting of omega-3-fatty acids and of conjugated linoleic acids for treating immunologically oriented clinical signs
AU2002951913A0 (en) * 2002-10-08 2002-10-24 Chevis Agriservices & Consulting Pty. Limited Method of treatment
CN1166368C (en) * 2003-02-26 2004-09-15 刘威 Seal oil cream and its prepn process and appplication in preparing intravenous injection
DE10361667A1 (en) * 2003-12-30 2005-07-28 Omega For Life Gmbh Novel fat powder
GB0403247D0 (en) 2004-02-13 2004-03-17 Tillotts Pharma Ag A pharmaceutical composition
US9012506B2 (en) 2004-09-28 2015-04-21 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
US8962023B2 (en) 2004-09-28 2015-02-24 Atrium Medical Corporation UV cured gel and method of making
US9000040B2 (en) 2004-09-28 2015-04-07 Atrium Medical Corporation Cross-linked fatty acid-based biomaterials
GB0425658D0 (en) 2004-11-22 2004-12-22 Stanford Rook Ltd Immunotherapeutic agent
US9278161B2 (en) 2005-09-28 2016-03-08 Atrium Medical Corporation Tissue-separating fatty acid adhesion barrier
US9427423B2 (en) 2009-03-10 2016-08-30 Atrium Medical Corporation Fatty-acid based particles
WO2008119146A2 (en) * 2007-03-29 2008-10-09 Dair, Bicudo Piai Combi-preparation of phosphoethanolamine and omega-3-fatty acid for treating bronchial asthma and copd
MX2010003651A (en) 2007-10-09 2010-07-05 Enzymotec Ltd Lipid compositions for the treatment of gastro-intestinal disorders and the promotion of intestinal development and maturation.
US8993625B2 (en) 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
US8241672B2 (en) * 2009-03-11 2012-08-14 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US9034389B2 (en) 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US20110038910A1 (en) 2009-08-11 2011-02-17 Atrium Medical Corporation Anti-infective antimicrobial-containing biomaterials
US20110200644A1 (en) * 2010-02-18 2011-08-18 Martek Biosciences Corporation DHA Ester Emulsions
WO2012009707A2 (en) 2010-07-16 2012-01-19 Atrium Medical Corporation Composition and methods for altering the rate of hydrolysis of cured oil-based materials
US9867880B2 (en) 2012-06-13 2018-01-16 Atrium Medical Corporation Cured oil-hydrogel biomaterial compositions for controlled drug delivery
GB201216385D0 (en) 2012-09-13 2012-10-31 Chrysalis Pharma Ag A pharmaceutical composition
DE102015115877A1 (en) * 2015-09-21 2017-03-23 Eberhard Karls Universität Tübingen Medizinische Fakultät Prophylaxis and treatment of cystic fibrosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4678808A (en) * 1985-10-15 1987-07-07 Baxter Travenol Laboratories, Inc. Rapid acting intravenous emulsions of omega-3 fatty acid esters
DE3734147C2 (en) * 1987-10-09 1998-10-29 Braun Melsungen Ag Isotonic omega-3 fatty acid-containing fat emulsion and its use

Also Published As

Publication number Publication date
DE59306981D1 (en) 1997-08-28
EP0637957A1 (en) 1995-02-15
GR3024526T3 (en) 1997-11-28
WO1993021912A1 (en) 1993-11-11
EP0637957B1 (en) 1997-07-23
JPH08500332A (en) 1996-01-16
ES2107663T3 (en) 1997-12-01
ATE155684T1 (en) 1997-08-15
JP3559039B2 (en) 2004-08-25

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