DK0559884T4 - Recombinant viral vectors for expression in muscle cells - Google Patents

Recombinant viral vectors for expression in muscle cells

Info

Publication number
DK0559884T4
DK0559884T4 DK92921684T DK92921684T DK0559884T4 DK 0559884 T4 DK0559884 T4 DK 0559884T4 DK 92921684 T DK92921684 T DK 92921684T DK 92921684 T DK92921684 T DK 92921684T DK 0559884 T4 DK0559884 T4 DK 0559884T4
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DK
Denmark
Prior art keywords
muscle cells
expression
vectors
viral vectors
recombinant viral
Prior art date
Application number
DK92921684T
Other languages
Danish (da)
Other versions
DK0559884T3 (en
Inventor
Michel Perricaudet
Pascale Briand
Leslie Stratford-Perricaudet
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9417378&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0559884(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of DK0559884T3 publication Critical patent/DK0559884T3/en
Publication of DK0559884T4 publication Critical patent/DK0559884T4/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Non-replicatable viral recombinant vectors which are recognizable by muscle cell receptors, and furthermore modified by an insertion nucleic acid coding for a polypeptide sequence to be expressed in said muscle cells, are used to obtain a drug for treating muscle cell diseases or diseases which, by virtue of their location in the body, are accessible to the products of the expression of the above mentioned nucleotide sequence, as secreted by said muscle cells. A method for producing said vectors, vectors such as those described above, and their use in pharmaceutical compositions are also provided.
DK92921684T 1991-09-27 1992-09-25 Recombinant viral vectors for expression in muscle cells DK0559884T4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9111947A FR2681786A1 (en) 1991-09-27 1991-09-27 RECOMBINANT VECTORS OF VIRAL ORIGIN, PROCESS FOR OBTAINING SAME AND THEIR USE FOR THE EXPRESSION OF POLYPEPTIDES IN MUSCLE CELLS.
PCT/FR1992/000898 WO1993006223A1 (en) 1991-09-27 1992-09-25 Viral recombinant vectors for expression in muscle cells

Publications (2)

Publication Number Publication Date
DK0559884T3 DK0559884T3 (en) 2000-10-02
DK0559884T4 true DK0559884T4 (en) 2004-08-02

Family

ID=9417378

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92921684T DK0559884T4 (en) 1991-09-27 1992-09-25 Recombinant viral vectors for expression in muscle cells

Country Status (12)

Country Link
EP (1) EP0559884B2 (en)
JP (1) JP3487597B2 (en)
AT (1) ATE192500T1 (en)
AU (1) AU666142B2 (en)
CA (1) CA2097185C (en)
DE (1) DE69230993T3 (en)
DK (1) DK0559884T4 (en)
ES (1) ES2147553T5 (en)
FR (1) FR2681786A1 (en)
GR (1) GR3034094T3 (en)
SG (1) SG49081A1 (en)
WO (1) WO1993006223A1 (en)

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US5919676A (en) * 1993-06-24 1999-07-06 Advec, Inc. Adenoviral vector system comprising Cre-loxP recombination
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KR20010020571A (en) 1997-06-30 2001-03-15 자끄 사비나 Improved method for transferring nucleic acid into the striped muscle and combination therefor
US6914131B1 (en) 1998-10-09 2005-07-05 Chiron S.R.L. Neisserial antigens
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Also Published As

Publication number Publication date
ES2147553T3 (en) 2000-09-16
GR3034094T3 (en) 2000-11-30
ES2147553T5 (en) 2004-11-16
JP3487597B2 (en) 2004-01-19
CA2097185A1 (en) 1993-03-28
AU666142B2 (en) 1996-02-01
EP0559884A1 (en) 1993-09-15
DE69230993T2 (en) 2000-11-30
JPH06502771A (en) 1994-03-31
CA2097185C (en) 2007-07-24
EP0559884B2 (en) 2004-04-07
DE69230993D1 (en) 2000-06-08
FR2681786A1 (en) 1993-04-02
WO1993006223A1 (en) 1993-04-01
FR2681786B1 (en) 1995-05-12
DK0559884T3 (en) 2000-10-02
AU2790292A (en) 1993-04-27
DE69230993T3 (en) 2004-12-16
ATE192500T1 (en) 2000-05-15
SG49081A1 (en) 1998-05-18
EP0559884B1 (en) 2000-05-03

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