DK0544740T3 - Process for converting R (-) - 2- (3-benzoylphenyl) propionic acid into S (+) isomer - Google Patents

Process for converting R (-) - 2- (3-benzoylphenyl) propionic acid into S (+) isomer

Info

Publication number
DK0544740T3
DK0544740T3 DK91914913.8T DK91914913T DK0544740T3 DK 0544740 T3 DK0544740 T3 DK 0544740T3 DK 91914913 T DK91914913 T DK 91914913T DK 0544740 T3 DK0544740 T3 DK 0544740T3
Authority
DK
Denmark
Prior art keywords
isomer
benzoylphenyl
converting
propionic acid
propionic
Prior art date
Application number
DK91914913.8T
Other languages
Danish (da)
Inventor
Claude Bertrand
Elie Fouque
Fur Isidore Le
Jean-Paul Richard
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of DK0544740T3 publication Critical patent/DK0544740T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Process for transforming (benzoyl-3 phenyl)-2 propionic-R(-) acid into an S(+) isomer through the action of a base either in situ during the splitting of racemic ketoprofen or on the crystallization mother liquor of a (benzoyl-3 phenyl)-2 propionic-S(+) acid salt.
DK91914913.8T 1990-08-20 1991-08-19 Process for converting R (-) - 2- (3-benzoylphenyl) propionic acid into S (+) isomer DK0544740T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9010460A FR2665897B1 (en) 1990-08-20 1990-08-20 PROCESS FOR THE CONVERSION OF ACID (BENZOYL-3 PHENYL) -2 PROPIONIC-R (-) TO THE S (+) ISOMER.

Publications (1)

Publication Number Publication Date
DK0544740T3 true DK0544740T3 (en) 1994-08-22

Family

ID=9399732

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91914913.8T DK0544740T3 (en) 1990-08-20 1991-08-19 Process for converting R (-) - 2- (3-benzoylphenyl) propionic acid into S (+) isomer

Country Status (19)

Country Link
EP (1) EP0544740B1 (en)
JP (1) JP3100059B2 (en)
AT (1) ATE108172T1 (en)
AU (1) AU8445691A (en)
CA (1) CA2089558A1 (en)
CS (1) CS256791A3 (en)
DE (1) DE69102767T2 (en)
DK (1) DK0544740T3 (en)
ES (1) ES2056657T3 (en)
FI (1) FI101880B (en)
FR (1) FR2665897B1 (en)
HU (1) HUT63373A (en)
IE (1) IE64689B1 (en)
NO (1) NO179001C (en)
NZ (1) NZ239435A (en)
PL (1) PL297972A1 (en)
PT (1) PT98726B (en)
WO (1) WO1992003404A1 (en)
ZA (1) ZA916496B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162576A (en) * 1991-04-15 1992-11-10 Ethyl Corporation Resolution of ketoprofen
WO1996023759A1 (en) * 1995-01-31 1996-08-08 Nagase & Company, Ltd. Method of racemizing optically active carboxylic acids
US6459878B1 (en) 1999-09-30 2002-10-01 Canon Kabushiki Kaisha Heating assembly, image-forming apparatus, and process for producing silicone rubber sponge and roller
CN102010327B (en) * 2009-09-07 2013-04-10 浙江九洲药业股份有限公司 Splitting method of (+/-)-2-(3-benzoyl)-phenylpropionic acid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1201726A (en) * 1959-06-20 1960-01-05 Process for obtaining flavonic derivatives from the leaves of certain plants
IT1175941B (en) * 1984-02-16 1987-08-12 Stabil Bioterapico Farmachim MONO, BI AND TRI-SUBSTITUTED ALUMINUM SALTS OF ARYL-ALCANOIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US4831147A (en) * 1988-07-05 1989-05-16 The Dow Chemical Company Resolution of enantiomers of herbicidal 2-(4-aryloxyphenoxy) propionates by chiral two-phase extraction
DE3824353A1 (en) * 1988-07-19 1990-01-25 Paz Arzneimittelentwicklung METHOD FOR SEPARATING MIXED ENANTIOMER ARYLPROPIONIC ACIDS

Also Published As

Publication number Publication date
CA2089558A1 (en) 1992-02-21
NZ239435A (en) 1993-04-28
ES2056657T3 (en) 1994-10-01
NO930546D0 (en) 1993-02-16
PT98726B (en) 1999-01-29
EP0544740A1 (en) 1993-06-09
FI101880B1 (en) 1998-09-15
FR2665897A1 (en) 1992-02-21
CS256791A3 (en) 1992-03-18
NO930546L (en) 1993-02-16
JP3100059B2 (en) 2000-10-16
IE912917A1 (en) 1992-02-26
DE69102767D1 (en) 1994-08-11
FR2665897B1 (en) 1994-03-18
FI101880B (en) 1998-09-15
FI930751A0 (en) 1993-02-19
JPH06501683A (en) 1994-02-24
NO179001B (en) 1996-04-09
ZA916496B (en) 1992-05-27
AU8445691A (en) 1992-03-17
HU9300469D0 (en) 1993-05-28
PL297972A1 (en) 1993-11-02
EP0544740B1 (en) 1994-07-06
ATE108172T1 (en) 1994-07-15
NO179001C (en) 1996-07-17
FI930751A (en) 1993-02-19
PT98726A (en) 1992-07-31
IE64689B1 (en) 1995-08-23
HUT63373A (en) 1993-08-30
WO1992003404A1 (en) 1992-03-05
DE69102767T2 (en) 1994-10-27

Similar Documents

Publication Publication Date Title
DK0612322T3 (en) Process for Separation of 5-Methyl-Tetrahydrofolic Acid
UA5560A1 (en) METHOD OF SEPARATION OF MIXTURE OF d-AND l-ENANTHIOMERS 4- [1-
ES2054039T3 (en) PROCEDURE FOR THE PREPARATION OF OPTICALLY ACTIVE PROPIONIC ARIL-2 ACIDS.
DE69309958T2 (en) METHOD FOR PRODUCING THE MAIN ENANTIOMERS OF PHENYL PROPIONIC ACIDS
ES2177644T3 (en) PROCEDURE FOR THE RESOLUTION OF ETODOLAC USING GLUCAMINE DERIVATIVES.
ATE72224T1 (en) PROCEDURE FOR THE OPTICAL RESOLUTION OF 2-(6-METHOXY-2-NAPHTYL)PROPIONIC ACID.
IT1217988B (en) PROCEDURE FOR THE OPTICAL RESOLUTION OF A PACEMO
DE59908211D1 (en) METHOD FOR THE RACEMATE CLEAVAGE OF 2-HYDROXYPROPIONIC ACIDS
DK0544740T3 (en) Process for converting R (-) - 2- (3-benzoylphenyl) propionic acid into S (+) isomer
DK82682A (en) METHOD FOR PREPARING THREO-2-HYDROXY-3- (4-METHOXYPHENYL) -3- (2-NITROPHENYLTHIO) PROPIONIC ACID ESTERS
DK147482A (en) METHOD FOR PREPARING D-2- (6-METHOXY-2-NAPHTHYL) -PROPIONIC ACID
ES467606A1 (en) Method for preparation of potically active 22aryle propionic acid
DK166271C (en) PROCEDURE FOR OPTICAL DIVISION OF RACEMIC MIXTURES OF ALFA-NAPHTHYL PROPIONIC ACIDS
DE3672127D1 (en) METHOD FOR OPTICALLY CLEAVING THE RAZEMIC MIXTURES OF ALPHA-NAPHTHYL PROPIONIC ACIDS.
DE68926521D1 (en) Process for the preparation of optically active 2-arylpropionic acid
JPS55118455A (en) Method of collecting optically active d-alpha-methyl-beta- mercapto propionic acid derivative
DK0474200T3 (en) Process for racemate cleavage of 2,2-dimethylcyclopropane carboxylic acid
LV5122A3 (en) Substrate (1R, Cis) -3- (Z-Chloro-3,3,3-trifluoroprop-1-en-1-yl) -2,2-dimethylcyclopropionic acid and (R) -alpha-cyano-3- (Z- 2-Chloro-3,3,3-trifluoro-prop-1-en-1-yl) -2,2-dimethylcyclopropionic acid (S) -alpha-cyano-3-phenoxybenzyl ester isomer crystalline enantiomeric para
RU99125069A (en) METHOD FOR PRODUCING ENANTIOMERS OF BIARILETHE-CARBOXYLIC ACIDS
DK440088D0 (en) METHOD FOR PREPARING N6-BENZYLOXYCARBONYL-2,6-DIAMINOPIMELY ACID
IT1261650B (en) Nepinalone enantiomers