DK0534655T3 - Thiazolidine-2,4-dione for the treatment of hypertension - Google Patents

Thiazolidine-2,4-dione for the treatment of hypertension

Info

Publication number
DK0534655T3
DK0534655T3 DK92308333.1T DK92308333T DK0534655T3 DK 0534655 T3 DK0534655 T3 DK 0534655T3 DK 92308333 T DK92308333 T DK 92308333T DK 0534655 T3 DK0534655 T3 DK 0534655T3
Authority
DK
Denmark
Prior art keywords
hypertension
thiazolidine
dione
treatment
choh
Prior art date
Application number
DK92308333.1T
Other languages
Danish (da)
Inventor
Eric Robert Larson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0534655T3 publication Critical patent/DK0534655T3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Removal Of Specific Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The use of a compound of formula (I): <CHEM> wherein X is C=0 or CHOH, or a pharmaceutically acceptable salt thereof, for the manufacture of medicaments for treating hypertension.
DK92308333.1T 1991-09-25 1992-09-14 Thiazolidine-2,4-dione for the treatment of hypertension DK0534655T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/765,643 US5175179A (en) 1991-09-25 1991-09-25 Method for treating hypertension

Publications (1)

Publication Number Publication Date
DK0534655T3 true DK0534655T3 (en) 1995-08-28

Family

ID=25074097

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92308333.1T DK0534655T3 (en) 1991-09-25 1992-09-14 Thiazolidine-2,4-dione for the treatment of hypertension

Country Status (17)

Country Link
US (1) US5175179A (en)
EP (1) EP0534655B1 (en)
JP (1) JPH05194220A (en)
KR (1) KR950013756B1 (en)
AT (1) ATE124259T1 (en)
AU (1) AU644545B2 (en)
CA (1) CA2078901A1 (en)
DE (1) DE69203194T2 (en)
DK (1) DK0534655T3 (en)
ES (1) ES2073871T3 (en)
HU (1) HUT65276A (en)
IL (1) IL103202A0 (en)
MX (1) MX9205408A (en)
MY (1) MY129918A (en)
NZ (1) NZ244474A (en)
TW (1) TW209167B (en)
ZA (1) ZA927307B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
ATE462703T1 (en) * 2004-08-25 2010-04-15 Actelion Pharmaceuticals Ltd BICYCLONONE DERIVATIVES AS RENIN INHIBITORS
KR100963455B1 (en) * 2005-05-27 2010-06-18 액테리온 파마슈티칼 리미티드 Novel piperidine carboxylic acid amide derivatives
AR059886A1 (en) * 2006-03-08 2008-05-07 Actelion Pharmaceuticals Ltd DERIVATIVES OF AMIDAS AS INHIBITORS OF RENINA

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX15171A (en) * 1988-03-08 1993-05-01 Pfizer DERIVATIVES OF TIAZOLIDINODIONA HIPOGLICEMICOS
GB8919417D0 (en) * 1989-08-25 1989-10-11 Beecham Group Plc Novel compounds
US5053420A (en) * 1989-10-13 1991-10-01 Pershadsingh Harrihar A Thiazolidine derivatives for the treatment of hypertension
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
JP2826379B2 (en) * 1990-01-22 1998-11-18 三共株式会社 A therapeutic agent for obesity hypertension comprising a thiazolidine derivative as an active ingredient
ATE93138T1 (en) * 1990-02-09 1993-09-15 Upjohn Co USE OF INSULIN SENSITIZING AGENTS TO TREAT HYPERTENSION.

Also Published As

Publication number Publication date
US5175179A (en) 1992-12-29
MY129918A (en) 2007-05-31
EP0534655A1 (en) 1993-03-31
NZ244474A (en) 1994-01-26
DE69203194T2 (en) 1995-11-02
HUT65276A (en) 1994-05-02
MX9205408A (en) 1993-03-01
DE69203194D1 (en) 1995-08-03
AU2532692A (en) 1993-04-22
JPH05194220A (en) 1993-08-03
KR950013756B1 (en) 1995-11-15
ES2073871T3 (en) 1995-08-16
CA2078901A1 (en) 1993-03-26
HU9203052D0 (en) 1992-12-28
ATE124259T1 (en) 1995-07-15
EP0534655B1 (en) 1995-06-28
TW209167B (en) 1993-07-11
IL103202A0 (en) 1993-02-21
AU644545B2 (en) 1993-12-09
KR930005621A (en) 1993-04-20
ZA927307B (en) 1994-03-24

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