DK0519600T3 - Fremgangsmåde og mellemprodukt til fremstilling af isoquinolinderivater - Google Patents

Fremgangsmåde og mellemprodukt til fremstilling af isoquinolinderivater

Info

Publication number
DK0519600T3
DK0519600T3 DK92304314.5T DK92304314T DK0519600T3 DK 0519600 T3 DK0519600 T3 DK 0519600T3 DK 92304314 T DK92304314 T DK 92304314T DK 0519600 T3 DK0519600 T3 DK 0519600T3
Authority
DK
Denmark
Prior art keywords
preparation
isoquinoline derivatives
isoquinoline
derivatives
tetrones
Prior art date
Application number
DK92304314.5T
Other languages
English (en)
Inventor
Michael Sotirios Malamas
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/703,969 external-priority patent/US5106978A/en
Priority claimed from GB929207634A external-priority patent/GB9207634D0/en
Application filed by American Home Prod filed Critical American Home Prod
Application granted granted Critical
Publication of DK0519600T3 publication Critical patent/DK0519600T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK92304314.5T 1991-05-22 1992-05-13 Fremgangsmåde og mellemprodukt til fremstilling af isoquinolinderivater DK0519600T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/703,969 US5106978A (en) 1991-05-22 1991-05-22 Process and intermediates for the preparation of spiro(isoquinoline-4(1H), 3'-pyrrolidine)-1,2', 3,5'(2H)-tetrones which are useful as aldose reductase inhibitors
GB929207634A GB9207634D0 (en) 1992-04-08 1992-04-08 Process and intermediate for the preparation of isoquinoline derivatives

Publications (1)

Publication Number Publication Date
DK0519600T3 true DK0519600T3 (da) 1997-12-29

Family

ID=26300672

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92304314.5T DK0519600T3 (da) 1991-05-22 1992-05-13 Fremgangsmåde og mellemprodukt til fremstilling af isoquinolinderivater

Country Status (13)

Country Link
EP (1) EP0519600B1 (da)
AT (1) ATE154356T1 (da)
AU (2) AU7765294A (da)
DE (1) DE69220291T2 (da)
DK (1) DK0519600T3 (da)
ES (1) ES2103890T3 (da)
FI (1) FI100330B (da)
GR (1) GR3024658T3 (da)
HK (1) HK1000321A1 (da)
HU (1) HU215589B (da)
IE (1) IE921641A1 (da)
NZ (1) NZ242856A (da)
SG (1) SG47769A1 (da)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6317885A (ja) * 1986-07-11 1988-01-25 Kyorin Pharmaceut Co Ltd スピロピロリジン−2,5−ジオン誘導体の製造方法
AU617541B2 (en) * 1988-10-20 1991-11-28 Wyeth Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors
US5106978A (en) * 1991-05-22 1992-04-21 American Home Products Corporation Process and intermediates for the preparation of spiro(isoquinoline-4(1H), 3'-pyrrolidine)-1,2', 3,5'(2H)-tetrones which are useful as aldose reductase inhibitors

Also Published As

Publication number Publication date
ES2103890T3 (es) 1997-10-01
FI922291A0 (fi) 1992-05-20
AU7765294A (en) 1995-01-12
AU657325B2 (en) 1995-03-09
NZ242856A (en) 1994-08-26
AU4531797A (en) 1998-02-05
ATE154356T1 (de) 1997-06-15
DE69220291D1 (de) 1997-07-17
GR3024658T3 (en) 1997-12-31
IE921641A1 (en) 1992-12-02
EP0519600B1 (en) 1997-06-11
EP0519600A1 (en) 1992-12-23
AU1639792A (en) 1992-11-26
FI100330B (fi) 1997-11-14
HK1000321A1 (en) 1998-02-27
HU9201692D0 (en) 1992-08-28
AU708608B2 (en) 1999-08-05
HU215589B (hu) 1999-01-28
HUT61547A (en) 1993-01-28
FI922291A (fi) 1992-11-23
DE69220291T2 (de) 1998-01-29
SG47769A1 (en) 1998-04-17

Similar Documents

Publication Publication Date Title
WO1998038168A1 (en) Isoquinolinone derivatives, process for preparing the same, and their use as phosphodiesterase inhibitors
SE9301241D0 (sv) Indole derivatives
AU2005280738A1 (en) Pyrrolo(3,2-c)pyridine derivatives and processes for the preparation thereof
PL293316A1 (en) Method of obtaining quinozolinone derivatives
PL309355A1 (en) Substituted pyrazoles as crf antagonists
EP0997461A4 (en) PROCESSES FOR THE PREPARATION OF PYRIDINIC DERIVATIVES
DK1236728T3 (da) S-type 2-substituerede hydroxy-2-indolidinylsmörsyreesterforbindelser og fremgangsmåde til fremstilling deraf
EP0314280A3 (en) Process for the preparation of fused pyridine compounds
ATE29883T1 (de) 5-alkyl-1,6-naphthyridin-2(1h)-one, zwischenprodukte, ihre herstellung und ihre verwendung als cardiotonica.
DK0519600T3 (da) Fremgangsmåde og mellemprodukt til fremstilling af isoquinolinderivater
CA2275253A1 (en) Method for producing n-substituted 3-hydroxypyrazoles
NO20041643L (no) Farmasoytisk akseptable salter av 20(S)-kamptoteciner
DK193090D0 (da) Imidazolyl- og pyridylderivater af phenylsubstituerede 1,4-dihydropyridiner og fremgangsmaade til fremstilling deraf
EP0481254A3 (en) 2-(4-Piperidinyl)-1H-pyrido[4,3-b]indol-1 ones and related compounds, intermediates and a process for their preparation
SU873882A3 (ru) Способ получени N-/1-(4-амино-2-хиназолинил)-3-или -4-пиперидил/-лактамов или их солей с кислотами
ES2042567T3 (es) Un procedimiento para la preparacion de un derivado de ergolina.
CA2378201A1 (en) New process for the preparation of spiro[(4-cyclohexanone)-[3h]indol]-2'[1'h]-one derivatives
HU9600597D0 (en) 4-alkylthio-pyrimidin-5-yl acetic acid derivates and fungicidal compositions containing them as an active ingredient
HU194170B (en) Process for production of derivatives of dihydropiridin with positive inotrop influence and medical compounds containing thereof
TH4773EX (th) อนุพันธ์ของควิโนลีน-3-คาร์บอกซิลิค แอซิตการเตรียมและการใช้สารเหล่านี้