DK0509338T3 - Preparation and Use of Stable Preparations of Small Particle Size Liposomes - Google Patents

Preparation and Use of Stable Preparations of Small Particle Size Liposomes

Info

Publication number
DK0509338T3
DK0509338T3 DK92105737.8T DK92105737T DK0509338T3 DK 0509338 T3 DK0509338 T3 DK 0509338T3 DK 92105737 T DK92105737 T DK 92105737T DK 0509338 T3 DK0509338 T3 DK 0509338T3
Authority
DK
Denmark
Prior art keywords
preparation
particle size
small particle
stable preparations
size liposomes
Prior art date
Application number
DK92105737.8T
Other languages
Danish (da)
Inventor
Edgar Dr Mentrup
Cristoph Michel
Thomas Dr Purmann
Original Assignee
Merz & Co Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz & Co Gmbh & Co filed Critical Merz & Co Gmbh & Co
Application granted granted Critical
Publication of DK0509338T3 publication Critical patent/DK0509338T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

The invention relates to liposome preparations, their manufacture and use, containing a lecithin with 1-90% of fatty acid-esterified collagen hydrolysate, optionally conventional gel formers, additives and pharmaceutical active substances, with a constant low vesicle size and high stability.
DK92105737.8T 1991-04-12 1992-04-03 Preparation and Use of Stable Preparations of Small Particle Size Liposomes DK0509338T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4111982A DE4111982C2 (en) 1991-04-12 1991-04-12 Stable small particulate liposome preparations, their preparation and use

Publications (1)

Publication Number Publication Date
DK0509338T3 true DK0509338T3 (en) 1995-09-18

Family

ID=6429461

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92105737.8T DK0509338T3 (en) 1991-04-12 1992-04-03 Preparation and Use of Stable Preparations of Small Particle Size Liposomes

Country Status (8)

Country Link
EP (1) EP0509338B1 (en)
JP (1) JPH0748247A (en)
AT (1) ATE126430T1 (en)
CA (1) CA2065579A1 (en)
DE (2) DE4111982C2 (en)
DK (1) DK0509338T3 (en)
ES (1) ES2077904T3 (en)
GR (1) GR3017147T3 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4306475A1 (en) * 1993-03-02 1994-09-08 Ensenat Pedro Gonzalez Liposomes containing chlorhexidine diacetate or chlorhexidine digluconate
DE9312509U1 (en) * 1993-08-20 1993-10-28 Euro Celtique Sa Preparations for external administration of antiseptic and / or wound healing promoting agents
US5863556A (en) * 1993-08-20 1999-01-26 Euro-Celtique, S.A. Preparations for the external application of antiseptic agents and/or agents promoting the healing of wounds
CA2140053C (en) * 1994-02-09 2000-04-04 Joel S. Rosenblatt Collagen-based injectable drug delivery system and its use
DE4430592A1 (en) 1994-08-20 1996-02-22 Max Delbrueck Centrum Liposomal preparation, its preparation and its use
FR2742988B1 (en) * 1996-01-03 1998-01-30 Oreal AQUEOUS COMPOSITION CONTAINING NON-IONIC LIPID VESICLES AND AT LEAST ONE NON-COATED PIGMENT DISPERSE IN THE AQUEOUS PHASE, PROCESS OF PREPARATION, USES
US6096863A (en) * 1996-08-23 2000-08-01 Regents Of The University Of Minnesota Self-assembling amphiphiles for construction of peptide secondary structures
CA2332389C (en) * 1998-05-27 2008-09-09 Wolfgang Fleischer Liposomal preparations for the application of antiseptic agents to the interior of the body
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
WO2000072823A1 (en) 1999-05-27 2000-12-07 Euroceltique S.A. Preparations for the application of anti-inflammatory agents
US7297344B1 (en) 1999-05-27 2007-11-20 Euro-Celtique, S.A. Preparations for the promotion of wound healing in the upper respiratory tract and/or ear
DE10128315B4 (en) * 2001-06-12 2004-12-02 Kuhs Gmbh & Co. Kg Phospholipid composition, use of such a phospholipid composition and preparation containing it
DE10203923B4 (en) * 2002-01-31 2011-06-01 Klinipharm Gmbh A method for increasing the water solubility of lipophilic active ingredients, preparation of highly concentrated aqueous compositions of these active ingredients, such products and their use
US20030180348A1 (en) * 2002-03-22 2003-09-25 Levinson R. Saul Transcellular drug delivery system
EP1585504A4 (en) * 2002-11-06 2009-07-15 Azaya Therapeutics Inc Protein-stabilized liposomal formulations of pharmaceutical agents
FR2870741B1 (en) * 2004-05-25 2008-03-14 Coletica Sa HYDRATED LAMELLAR OR LIPOSOME PHASE CONTAINING A FATTY MONOAMINE OR A CATIONIC POLYMER PROMOTING INTERCELLULAR PENETRATION AND A COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING THE SAME.
US8053000B2 (en) 2005-06-07 2011-11-08 Dr. Reddy's Laboratories Limited Compositions for drug delivery
DE102006015271A1 (en) * 2006-04-01 2007-10-11 Lohmann & Rauscher Gmbh & Co. Kg Biguanide-containing liposomes
CN103200932A (en) * 2010-06-23 2013-07-10 布莱特赛德创新有限公司 Lecithin carrier vesicles and methods of making the same
WO2013123466A1 (en) * 2012-02-16 2013-08-22 Brightside Innovations, Inc. Dietary and nutritional compositions and methods of use
EP2708264B1 (en) * 2012-09-13 2017-10-04 PM-International AG Cosmetic two component preparation for separate storage of compositions comprising liposomes of coenzyme Q10 and fluorocarbons

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE43327T1 (en) * 1980-07-01 1983-01-05 L'Oreal, 75008 Paris METHOD FOR PRODUCING STABLE DISPERSIONS IN AN AQUEOUS PHASE OF AT LEAST ONE LIQUID, NOT WATER-MISCIPABLE, AND THE CORRESPONDING DISPERSIONS.
FR2571963B1 (en) * 1984-10-24 1987-07-10 Oreal COMPOSITION FOR COSMETIC OR PHARMACEUTICAL USE CONTAINING NIOSOMES AND AT LEAST ONE WATER-SOLUBLE POLYAMIDE AND PROCESS FOR PREPARING THE SAME.
FR2597345B1 (en) * 1986-04-22 1990-08-03 Oreal COSMETIC OR PHARMACEUTICAL COMPOSITION BASED ON AN AQUEOUS DISPERSION OF LIPID SPHERULES.
FR2622104B1 (en) * 1987-10-22 1990-03-30 Bioetica Sa METHOD FOR STABILIZING HYDRATED LIPID LAMELLAR PHASES, FOR EXAMPLE. OF LIPOSOMES, COMPOSITION OF HYDRATED LIPID LAMELLAR PHASES, EG. LIPOSOMES, STABILIZED BY THE USE OF A STABILIZING MEDIUM BASED ON ATELOCOLLAGEN AND GLYCOSAMINOGLYCANS AND USE IN PHARMACY OR COSMETOLOGY
IL94103A0 (en) * 1989-04-25 1991-01-31 Nattermann A & Cie Water-containing formulations with phospholipids,their preparation and application

Also Published As

Publication number Publication date
GR3017147T3 (en) 1995-11-30
ES2077904T3 (en) 1995-12-01
CA2065579A1 (en) 1992-10-13
JPH0748247A (en) 1995-02-21
EP0509338B1 (en) 1995-08-16
ATE126430T1 (en) 1995-09-15
DE4111982C2 (en) 1998-12-24
DE4111982A1 (en) 1992-10-15
DE59203259D1 (en) 1995-09-21
EP0509338A1 (en) 1992-10-21

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