DK0466933T3 - Bicyclolactamderivat - Google Patents

Bicyclolactamderivat

Info

Publication number
DK0466933T3
DK0466933T3 DK91903619.4T DK91903619T DK0466933T3 DK 0466933 T3 DK0466933 T3 DK 0466933T3 DK 91903619 T DK91903619 T DK 91903619T DK 0466933 T3 DK0466933 T3 DK 0466933T3
Authority
DK
Denmark
Prior art keywords
effect
bicyclolactam
cerebral
cyano
nitro
Prior art date
Application number
DK91903619.4T
Other languages
Danish (da)
English (en)
Inventor
Akihiro Kawaguchi
Atsushi Satoh
Makoto Kajitani
Mitsugi Yasumoto
Junji Yamamoto
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DK0466933T3 publication Critical patent/DK0466933T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DK91903619.4T 1990-02-02 1991-01-30 Bicyclolactamderivat DK0466933T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2475490 1990-02-02

Publications (1)

Publication Number Publication Date
DK0466933T3 true DK0466933T3 (da) 1996-01-02

Family

ID=12146933

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91903619.4T DK0466933T3 (da) 1990-02-02 1991-01-30 Bicyclolactamderivat

Country Status (13)

Country Link
US (1) US5185344A (de)
EP (2) EP0668268A3 (de)
JP (1) JP2676170B2 (de)
KR (1) KR940004059B1 (de)
AT (1) ATE130605T1 (de)
AU (1) AU627399B2 (de)
CA (1) CA2050587C (de)
DE (1) DE69114778T2 (de)
DK (1) DK0466933T3 (de)
ES (1) ES2083568T3 (de)
GR (1) GR3018235T3 (de)
HU (1) HU211635A9 (de)
WO (1) WO1991011434A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159987A (en) * 1994-03-28 2000-12-12 Taiho Pharmaceuticals, Co. Bicyclolactam compounds, use thereof and intermediates for preparing thereof
HU221727B1 (hu) * 1994-03-28 2002-12-28 Taiho Pharmaceutical Co. Ltd. Hidroxi-biciklolaktám-származékok, alkalmazásuk és ilyen vegyületeket tartalmazó gyógyászati készítmények
JP3161948B2 (ja) * 1995-06-12 2001-04-25 大鵬薬品工業株式会社 ビシクロラクタム化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619937A (en) * 1984-02-02 1986-10-28 Warner-Lambert Company Saturated bicyclic lactam acids and derivatives as cognition activators
US4758585A (en) * 1985-08-16 1988-07-19 Warner-Lambert Company Saturated cycloalkyl (B) pyrrol-1 (2H)- acetic acid amides and derivatives thereof
US4621097A (en) * 1985-08-16 1986-11-04 Warner-Lambert Company Saturated cycloalkyl[c] pyrrole-2(1H)-acetic acid amides and derivatives thereof

Also Published As

Publication number Publication date
ES2083568T3 (es) 1996-04-16
KR920701154A (ko) 1992-08-11
EP0466933A1 (de) 1992-01-22
WO1991011434A1 (fr) 1991-08-08
EP0668268A2 (de) 1995-08-23
CA2050587C (en) 1997-11-25
KR940004059B1 (ko) 1994-05-11
US5185344A (en) 1993-02-09
EP0668268A3 (de) 1995-08-30
DE69114778T2 (de) 1996-04-18
JP2676170B2 (ja) 1997-11-12
AU7186691A (en) 1991-08-21
HU211635A9 (en) 1995-12-28
GR3018235T3 (en) 1996-02-29
AU627399B2 (en) 1992-08-20
ATE130605T1 (de) 1995-12-15
CA2050587A1 (en) 1991-08-03
DE69114778D1 (de) 1996-01-04
EP0466933B1 (de) 1995-11-22
EP0466933A4 (en) 1992-07-08

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