DK0431151T3 - Fremgangsmåde til fremstilling af 21-brom-4-pregnen-3,20-dion-derivater - Google Patents

Fremgangsmåde til fremstilling af 21-brom-4-pregnen-3,20-dion-derivater

Info

Publication number
DK0431151T3
DK0431151T3 DK90915942.8T DK90915942T DK0431151T3 DK 0431151 T3 DK0431151 T3 DK 0431151T3 DK 90915942 T DK90915942 T DK 90915942T DK 0431151 T3 DK0431151 T3 DK 0431151T3
Authority
DK
Denmark
Prior art keywords
group
pct
hydrogen atom
bromo
preparation
Prior art date
Application number
DK90915942.8T
Other languages
Danish (da)
English (en)
Inventor
Gerhard Hempel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0431151T3 publication Critical patent/DK0431151T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK90915942.8T 1989-05-12 1990-05-07 Fremgangsmåde til fremstilling af 21-brom-4-pregnen-3,20-dion-derivater DK0431151T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3915951A DE3915951C1 (US07223432-20070529-C00017.png) 1989-05-12 1989-05-12

Publications (1)

Publication Number Publication Date
DK0431151T3 true DK0431151T3 (da) 1995-07-24

Family

ID=6380760

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90915942.8T DK0431151T3 (da) 1989-05-12 1990-05-07 Fremgangsmåde til fremstilling af 21-brom-4-pregnen-3,20-dion-derivater

Country Status (10)

Country Link
US (1) US5332847A (US07223432-20070529-C00017.png)
EP (1) EP0431151B1 (US07223432-20070529-C00017.png)
JP (1) JP2842690B2 (US07223432-20070529-C00017.png)
AT (1) ATE119912T1 (US07223432-20070529-C00017.png)
CA (1) CA2033065A1 (US07223432-20070529-C00017.png)
DD (1) DD297975A5 (US07223432-20070529-C00017.png)
DE (2) DE3915951C1 (US07223432-20070529-C00017.png)
DK (1) DK0431151T3 (US07223432-20070529-C00017.png)
ES (1) ES2071832T3 (US07223432-20070529-C00017.png)
WO (1) WO1990013558A1 (US07223432-20070529-C00017.png)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5929262A (en) * 1995-03-30 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3557158A (en) * 1962-01-22 1971-01-19 Upjohn Co 6alpha-fluoro-16-methyl - 4 - pregnene 3,20-diones and intermediates produced in the synthesis thereof
US3646012A (en) * 1967-10-05 1972-02-29 Wyeth John & Brother Ltd Enamine salt protection of steroidal alpha beta-unsaturated ketones
DE2118218A1 (en) * 1971-04-10 1972-10-26 Schering Ag, 1000 Berlin Und 4619 Bergkamen Tetrahalo steroids - prepd by simultaneous addn of fluorine and chlorine on the delta 9(11)-double bond
YU54476A (en) * 1975-03-31 1982-05-31 Taisho Pharmaceutical Co Ltd Process for obtaining 17-ester 21-halo-pregnane
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
DE3400188A1 (de) * 1984-01-02 1985-07-11 Schering AG, Berlin und Bergkamen, 1000 Berlin Neue 6(alpha),16(alpha)-dimethylkortikoide
DE3640709A1 (de) * 1986-11-28 1988-06-09 Schering Ag Verfahren zur herstellung von 6(alpha),9(alpha)-difluor-11ss,17(alpha)-dihydroxy-16(alpha)-methyl-4-pregnen-3,20-dion und dessen derivate

Also Published As

Publication number Publication date
EP0431151A1 (de) 1991-06-12
JPH04500680A (ja) 1992-02-06
US5332847A (en) 1994-07-26
DE59008713D1 (de) 1995-04-20
EP0431151B1 (de) 1995-03-15
ATE119912T1 (de) 1995-04-15
DD297975A5 (de) 1992-01-30
DE3915951C1 (US07223432-20070529-C00017.png) 1990-09-13
ES2071832T3 (es) 1995-07-01
WO1990013558A1 (de) 1990-11-15
CA2033065A1 (en) 1990-11-13
JP2842690B2 (ja) 1999-01-06

Similar Documents

Publication Publication Date Title
AU7554987A (en) Solutions of oxazaphosphorins having improved stability and process for the preparation thereof
PT79839A (en) Process for the preparation of 6,6-ethylene-15,16-methylene-3-oxi-17alpha-pregn-4-ene-21,17-carbolactones and pharmaceutical compositions therewith
AU4889579A (en) 3,20-dioxo-4,9-diene-21-hydroxyl steroid derivatives
DK288686A (da) Farmaceutiske praeparater
ES8504778A1 (es) Un procedimiento para la preparacion de derivados de fenil-piperazina
ES8702433A1 (es) Un procedimiento para la preparacion de un compuesto heterociclico sustituido con peptidos.
ES8203855A1 (es) Un procedimiento para la preparacion de derivados de imida- lol.
GR900100035A (el) Παράγωγα υδροξυαλκανοκαρβονικού οξέος, η παρασευή και η χρησιμοπποίηση τους.
HUT50845A (en) Process for producing 14,17beta-ethano-14beta-estratrienes and pharmaceutical compositions comprising same
DK0431151T3 (da) Fremgangsmåde til fremstilling af 21-brom-4-pregnen-3,20-dion-derivater
GR3021337T3 (en) A new process for the preparation of 20-keto, 21-alpha-hydroxy steroids and intermediates therefor
DK0440752T3 (da) Fremgangsmåde til fremstilling af 3-desoxy-4-en-steroider
AU9181382A (en) Di-and-tetrahydroguinolylacetic acid esters
DE3564426D1 (en) Polyprenyl compound, process of producing it and pharmaceutical use
ATE77744T1 (de) Verwendung von pyrrothinderivaten.
ES469510A1 (es) Procedimiento para la preparacion de 17beta hidroxi-4-an- drosten-3-onas.
ES8405033A1 (es) Procedimiento para la obtencion de esteroides dihalogenados.
AU7351787A (en) 2,2,6,6-diethylene-3-oxo-17-alpha-pregn-4-en-21,17- carbolactones
ATE18223T1 (de) Ergolinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ES8300752A1 (es) "un procedimiento para la preparacion de derivados de n-ftalidil-5-fluorouracilo".
ATE130309T1 (de) 14alpha,16alpha-ethano- und 14alpha,16alpha- ethenoestratriene.
GB2022583A (en) New ionic polyiodo benzene derivatives useful as X-ray contrast media