DK0394050T3 - Fremgangsmåde til fremstilling af en frysetørret formulering, som indeholder et lægemiddel - Google Patents

Fremgangsmåde til fremstilling af en frysetørret formulering, som indeholder et lægemiddel

Info

Publication number
DK0394050T3
DK0394050T3 DK90304230T DK90304230T DK0394050T3 DK 0394050 T3 DK0394050 T3 DK 0394050T3 DK 90304230 T DK90304230 T DK 90304230T DK 90304230 T DK90304230 T DK 90304230T DK 0394050 T3 DK0394050 T3 DK 0394050T3
Authority
DK
Denmark
Prior art keywords
freeze
frozen
liquid
drug
preparing
Prior art date
Application number
DK90304230T
Other languages
English (en)
Inventor
Seigo Ueda
Takashi Shiokari
Kunio Hashi
Akira Kusai
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of DK0394050T3 publication Critical patent/DK0394050T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/40—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by drying or kilning; Subsequent reconstitution
    • A23L3/44—Freeze-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
DK90304230T 1989-04-18 1990-04-18 Fremgangsmåde til fremstilling af en frysetørret formulering, som indeholder et lægemiddel DK0394050T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9856189 1989-04-18

Publications (1)

Publication Number Publication Date
DK0394050T3 true DK0394050T3 (da) 2002-02-11

Family

ID=14223093

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90304230T DK0394050T3 (da) 1989-04-18 1990-04-18 Fremgangsmåde til fremstilling af en frysetørret formulering, som indeholder et lægemiddel

Country Status (17)

Country Link
US (1) US5044091B1 (da)
EP (1) EP0394050B1 (da)
JP (1) JPH07116022B2 (da)
KR (1) KR950007908B1 (da)
AT (1) ATE210427T1 (da)
AU (1) AU624494B2 (da)
CA (1) CA2014714C (da)
DE (1) DE69033874T2 (da)
DK (1) DK0394050T3 (da)
ES (1) ES2165839T3 (da)
FI (1) FI104360B (da)
HK (1) HK1010685A1 (da)
HU (1) HU204993B (da)
NO (1) NO180801C (da)
NZ (1) NZ233344A (da)
PH (1) PH27522A (da)
ZA (1) ZA902909B (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
US5169834A (en) * 1990-11-30 1992-12-08 American Cyanamid Company Compositions and method for reducing vial breakage during lyophilization
GR910100193A (el) * 1991-05-03 1993-03-31 Mediventures Inc Παρασκευη φαρμακευτικων και αλλων περιβληματων με διαλυση σε στερεα κατασταση.
US5362442A (en) 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
US20040067157A1 (en) * 1993-07-22 2004-04-08 Clearant, Inc. Methods for sterilizing biological materials
DE19547973C2 (de) * 1995-12-21 1999-08-12 Plantamed Arzneimittel Gmbh Verfahren zur schonenden Keimreduzierung von pharmazeutischen Zubereitungen
IL120202A (en) * 1996-03-07 2001-03-19 Akzo Nobel Nv Container with freeze-dried vaccine components
KR100595340B1 (ko) * 1998-01-21 2006-07-03 다케다 야쿠힌 고교 가부시키가이샤 서방형 제제의 동결 건조법
US20040086420A1 (en) * 2000-03-23 2004-05-06 Macphee Martin J. Methods for sterilizing serum or plasma
US6682695B2 (en) * 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
US6696060B2 (en) 2001-06-14 2004-02-24 Clearant, Inc. Methods for sterilizing preparations of monoclonal immunoglobulins
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
US6946098B2 (en) 2001-08-10 2005-09-20 Clearant, Inc. Methods for sterilizing biological materials
US7252799B2 (en) * 2001-08-31 2007-08-07 Clearant, Inc. Methods for sterilizing preparations containing albumin
US6749851B2 (en) 2001-08-31 2004-06-15 Clearant, Inc. Methods for sterilizing preparations of digestive enzymes
US20030095890A1 (en) * 2001-09-24 2003-05-22 Shirley Miekka Methods for sterilizing biological materials containing non-aqueous solvents
US20030185702A1 (en) * 2002-02-01 2003-10-02 Wilson Burgess Methods for sterilizing tissue
US20110091353A1 (en) * 2001-09-24 2011-04-21 Wilson Burgess Methods for Sterilizing Tissue
US6783968B2 (en) 2001-09-24 2004-08-31 Clearant, Inc. Methods for sterilizing preparations of glycosidases
US20030124023A1 (en) * 2001-12-21 2003-07-03 Wilson Burgess Method of sterilizing heart valves
US7387796B2 (en) * 2002-01-30 2008-06-17 Hebert Rolland F Stable compositions of S-adenosyl-l-methionine with dextran
US20030180181A1 (en) * 2002-02-01 2003-09-25 Teri Greib Methods for sterilizing tissue
US6908591B2 (en) * 2002-07-18 2005-06-21 Clearant, Inc. Methods for sterilizing biological materials by irradiation over a temperature gradient
US20040013562A1 (en) * 2002-07-18 2004-01-22 Wilson Burgess Methods for sterilizing milk.
JP2006111532A (ja) * 2004-10-12 2006-04-27 Yoshindo:Kk パニペネム含有ダブルバッグ型製剤
EP1870649A1 (en) * 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
TWI343262B (en) * 2006-09-26 2011-06-11 Schering Corp Rapidly disintegrating lyophilized oral formulations of a thrombin receptor antagonist
US10548839B2 (en) * 2010-03-16 2020-02-04 Wei Tian Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form
CA2876946A1 (en) 2012-06-26 2014-01-03 Bioneer A/S A syringe with a hollow plunger
JP6968184B2 (ja) 2016-10-25 2021-11-17 キャタレント・ユーケー・スウィンドン・ザイディス・リミテッド 速崩壊多層錠のための異なる密度の組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB797774A (en) * 1955-03-02 1958-07-09 Armour & Co Improvements in and relating to the production and packaging of stratiform products
US3616543A (en) * 1969-10-31 1971-11-02 Merck & Co Inc Method of producing a multicomponent lyophilized product
FR2109201A6 (da) * 1970-10-07 1972-05-26 Air Liquide
EP0069176A1 (en) * 1981-07-03 1983-01-12 American Home Products Corporation Method of obtaining a lyophilized product
US4433558A (en) * 1981-08-25 1984-02-28 Cheng Chen Yen Parallel contact distillative freezing process for separating volatile mixtures and apparatuses for use therein
EP0081913B1 (en) * 1981-12-11 1985-06-26 JOHN WYETH & BROTHER LIMITED Process and apparatus for freezing a liquid medium
US4430807A (en) * 1982-05-17 1984-02-14 The Dow Chemical Company Process for drying water-wet membranes
JPS6168412A (ja) * 1984-09-10 1986-04-08 Fujisawa Pharmaceut Co Ltd 医薬品の凍結乾燥方法
IL78930A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Lyophilized emulsion compositions for parenteral administration
FR2601702A1 (fr) * 1986-07-21 1988-01-22 Atochem Composition a base de chlorure de methylene - son utilisation pour le degraissage des metaux

Also Published As

Publication number Publication date
ES2165839T3 (es) 2002-04-01
NO901691D0 (no) 1990-04-17
CA2014714A1 (en) 1990-10-18
FI901947A0 (fi) 1990-04-18
JPH07116022B2 (ja) 1995-12-13
AU5328990A (en) 1990-10-25
ATE210427T1 (de) 2001-12-15
EP0394050A2 (en) 1990-10-24
AU624494B2 (en) 1992-06-11
NO180801C (no) 1997-07-02
KR900015715A (ko) 1990-11-10
JPH0347115A (ja) 1991-02-28
US5044091B1 (en) 1997-12-30
FI104360B (fi) 2000-01-14
DE69033874D1 (de) 2002-01-24
HU902472D0 (en) 1990-08-28
NO901691L (no) 1990-10-19
NZ233344A (en) 1991-05-28
EP0394050B1 (en) 2001-12-12
CA2014714C (en) 2000-07-18
US5044091A (en) 1991-09-03
NO180801B (no) 1997-03-24
HK1010685A1 (en) 1999-06-25
PH27522A (en) 1993-08-18
ZA902909B (en) 1991-12-24
KR950007908B1 (ko) 1995-07-21
HU204993B (en) 1992-03-30
HUT54885A (en) 1991-04-29
DE69033874T2 (de) 2002-08-29
EP0394050A3 (en) 1992-06-10

Similar Documents

Publication Publication Date Title
DK0394050T3 (da) Fremgangsmåde til fremstilling af en frysetørret formulering, som indeholder et lægemiddel
NO862689D0 (no) Dehydratisert kapsel, samt fremgangsmaate for fremstilling av en slik.
IT8720689A0 (it) Procedimento e impianto per la separazione di sostanze leggere da miscele di substrati.
DE3872382D1 (de) Pharmazeutische zusammensetzungen mit verlaengerter wirkung und verfahren zu ihrer herstellung.
DE3783356T2 (de) Benzimidazolderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
FI874210A0 (fi) Alfa-olefiinien stereospesifisessä polymeroinnissa käyttökelpoinen kiinteä katalysaattorikompleksi, menetelmä sen valmistamiseksi ja menetelmä alfa-olefiinien polymeroimiseksi tämän katalysaattorikompleksin läsnäollessa
DE69009237T2 (de) Verfahren zur Herstellung von optisch aktiven Estern der 6-t-Butoxy-3,5-dihydroxyhexansäure.
DE3777122D1 (de) Alkansulfonanilid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ATE78263T1 (de) Verfahren zur herstellung eines produkts von geliertem cellulosetriacetat und das so hergestellte produkt.
DE3766299D1 (de) 4-chinolon-3-carbonsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
NO874355L (no) Fremgangsmaate for fremstilling av glycolipid som inneholder n-glycolylneuraminsyre.
DE68921131D1 (de) Verfahren zur Herstellung von Bis(aminopropoxy)alkanen.
IT8621230A0 (it) Policarbonati ramificati contenenti acidi alifatici policarbossilici o loro derivati e procedimento per la loro preparazione.
PT85100A (pt) Processo para a preparacao de novos tetra-hidro-benzotiazois e de composicoes farmaceuticas que os contem
TH8834EX (th) วิธีการเตรียมสารสูตรผสมที่ทำให้แห้งแบบเยือกแข็งซึ่งประกอบด้วยยา
PT85879A (pt) Processo para a preparacao de derivados de imidazo {4,5-b}piridinona-2 e de composicoes farmaceuticas que os contem
ES2016824B3 (es) Poliuretanos preparados a partir de polioles que contienen cristales liquidos y proceso para la preparacion de los mismos.
DE3790355T (de) Verfahren zur herstellung magensalzsaeureneutralisierender pharmazeutischer praeparate mit grosser saeurebindender kapazitaet, verzoegerter wirkungsdauer und vergroesserter bioverfuegbarkeit
DE68928788T2 (de) Verfahren zur Herstellung von optisch aktiven 3,4-Dihydroxybuttersäurederivaten
FI873548A0 (fi) Menetelmä oktreotidiä sisältävän farmaseuttisen koostumuksen valmistamiseksi
NO880818D0 (no) Forbedringer i utstyr for injeksjon av stoffer inn i vaesker.
NO880998D0 (no) Forbedringer i dyser for injeksjon av stoffer inn i vaesker
NO167622C (no) Fremgangsmaate for tilsetning av flytende stoffer til produkter, eksempelvis forpellets som er fremstilt ved ekstrudering.
ATE98215T1 (de) Verfahren zur herstellung von 2-oxo-3aromatischen karbonsaeure-derivaten.