DE8259T1 - New piperidylbenxime kUioUnon derivatives, process for their preparation and pharmaceutical preparations containing them - Google Patents
New piperidylbenxime kUioUnon derivatives, process for their preparation and pharmaceutical preparations containing themInfo
- Publication number
- DE8259T1 DE8259T1 DE1979400509 DE79400509T DE8259T1 DE 8259 T1 DE8259 T1 DE 8259T1 DE 1979400509 DE1979400509 DE 1979400509 DE 79400509 T DE79400509 T DE 79400509T DE 8259 T1 DE8259 T1 DE 8259T1
- Authority
- DE
- Germany
- Prior art keywords
- group
- general formula
- piperidylbenzimidazolinone
- meanings given
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title claims 4
- 238000002360 preparation method Methods 0.000 title claims 4
- 238000000034 method Methods 0.000 title claims 3
- -1 formamido group Chemical group 0.000 claims 10
- 150000001875 compounds Chemical class 0.000 claims 8
- 125000004435 hydrogen atoms Chemical group [H]* 0.000 claims 6
- ICTZOWVELHATOU-UHFFFAOYSA-N 3-piperidin-1-yl-1H-benzimidazol-2-one Chemical class O=C1NC2=CC=CC=C2N1N1CCCCC1 ICTZOWVELHATOU-UHFFFAOYSA-N 0.000 claims 5
- 125000004432 carbon atoms Chemical group C* 0.000 claims 3
- 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000001951 carbamoylamino group Chemical group C(N)(=O)N* 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 claims 2
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 claims 2
- 125000006239 protecting group Chemical group 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 125000004203 4-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 208000006673 Asthma Diseases 0.000 claims 1
- 206010003816 Autoimmune disease Diseases 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 230000002152 alkylating Effects 0.000 claims 1
- 125000005466 alkylenyl group Chemical group 0.000 claims 1
- 201000005794 allergic hypersensitivity disease Diseases 0.000 claims 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 claims 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 150000003944 halohydrins Chemical class 0.000 claims 1
- 200000000018 inflammatory disease Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 claims 1
- 230000001681 protective Effects 0.000 claims 1
- 230000029058 respiratory gaseous exchange Effects 0.000 claims 1
- OJUGVDODNPJEEC-UHFFFAOYSA-N α-oxobenzeneacetaldehyde Chemical compound O=CC(=O)C1=CC=CC=C1 OJUGVDODNPJEEC-UHFFFAOYSA-N 0.000 claims 1
Claims (11)
(πΙΙ N-CO-NH-) oder eine SuIfamoylaminogruppean acetamido group (CH - CO-NH-), a mesylamino group (CH-SO-NH-), an oxalamino group (HOOC-CO-NH-), an ethoxalylamino group (CH OOC-CO-NH-), a carbamoy! group (, 7 "" N-CO-), an ureido group
( πΙΙ N-CO-NH-) or a sulfamoylamino group
gleichartig sein und jeweils Wasserstoffatome oder
Alkylgruppen mit 1 bis 5 Kohlenstoffatomen darstellen können,where R 'and R "in these formulas are identical or
be of the same type and each hydrogen atoms or
Can represent alkyl groups with 1 to 5 carbon atoms,
bedeuten.5 carbon atoms
mean.
' :; 'V . : - ■ oxo-benzimidazoline-1-yl) piperidine.
':;'V. : - ■
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH784478 | 1978-07-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE8259T1 true DE8259T1 (en) | 1980-09-04 |
Family
ID=
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