DE69941791D1 - Von blutplättchen abstammender wachstumsfaktor d, dafür kodierende dns und deren verwendungen - Google Patents

Von blutplättchen abstammender wachstumsfaktor d, dafür kodierende dns und deren verwendungen

Info

Publication number
DE69941791D1
DE69941791D1 DE69941791T DE69941791T DE69941791D1 DE 69941791 D1 DE69941791 D1 DE 69941791D1 DE 69941791 T DE69941791 T DE 69941791T DE 69941791 T DE69941791 T DE 69941791T DE 69941791 D1 DE69941791 D1 DE 69941791D1
Authority
DE
Germany
Prior art keywords
dna
codes
derived
growth factor
blood plate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69941791T
Other languages
English (en)
Inventor
Ulf Eriksson
Karin Aase
Annica Ponten
Xuri Li
Marko Uutela
Kari Alitalo
Arne Oestman
Carl-Henrik Heldin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ludwig Institute for Cancer Research Ltd
Licentia Oy
Ludwig Institute for Cancer Research New York
Original Assignee
Ludwig Institute for Cancer Research Ltd
Licentia Oy
Ludwig Institute for Cancer Research New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Institute for Cancer Research Ltd, Licentia Oy, Ludwig Institute for Cancer Research New York filed Critical Ludwig Institute for Cancer Research Ltd
Application granted granted Critical
Publication of DE69941791D1 publication Critical patent/DE69941791D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69941791T 1998-11-10 1999-11-10 Von blutplättchen abstammender wachstumsfaktor d, dafür kodierende dns und deren verwendungen Expired - Lifetime DE69941791D1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US10785298P 1998-11-10 1998-11-10
US11399798P 1998-12-28 1998-12-28
US15060499P 1999-08-26 1999-08-26
US15710899P 1999-10-04 1999-10-04
US15775699P 1999-10-05 1999-10-05
PCT/US1999/026462 WO2000027879A1 (en) 1998-11-10 1999-11-10 Platelet-derived growth factor d, dna coding therefor, and uses thereof

Publications (1)

Publication Number Publication Date
DE69941791D1 true DE69941791D1 (de) 2010-01-21

Family

ID=27537197

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69941791T Expired - Lifetime DE69941791D1 (de) 1998-11-10 1999-11-10 Von blutplättchen abstammender wachstumsfaktor d, dafür kodierende dns und deren verwendungen

Country Status (12)

Country Link
US (1) US6706687B1 (de)
EP (2) EP2151454B1 (de)
JP (1) JP2002534061A (de)
CN (1) CN1261453C (de)
AT (2) ATE556090T1 (de)
AU (1) AU770899B2 (de)
CA (1) CA2349951A1 (de)
DE (1) DE69941791D1 (de)
DK (1) DK1129110T3 (de)
ES (1) ES2336731T3 (de)
NZ (1) NZ511379A (de)
WO (1) WO2000027879A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000066736A1 (en) * 1999-05-03 2000-11-09 Zymogenetics, Inc. Growth factor homolog zvegf4
US6468543B1 (en) * 1999-05-03 2002-10-22 Zymogenetics, Inc. Methods for promoting growth of bone using ZVEGF4
US6630142B2 (en) 1999-05-03 2003-10-07 Zymogenetics, Inc. Method of treating fibroproliferative disorders
AU7868000A (en) * 1999-10-07 2001-05-10 Curagen Corporation Growth factor polypeptides and nucleic acids encoding same
AU2001272902A1 (en) * 2000-05-19 2001-12-03 Eli Lilly And Company Treating musculoskeletal disorders using lp85 and analogs thereof
CA2427143A1 (en) 2000-10-30 2002-08-08 Zymogenetics, Inc. Compositions and methods for improving kidney function
WO2002059618A2 (en) * 2000-11-16 2002-08-01 Curagen Corporation Growth factor polypeptides and nucleic acids encoding same
ATE384783T1 (de) * 2001-10-19 2008-02-15 Zymogenetics Inc Dimerisierter wachstumsfaktor sowie materialien und verfahren zu seiner herstellung
US7135174B2 (en) * 2002-01-07 2006-11-14 Amgen Fremont, Inc. Antibodies directed to PDGFD and uses thereof
CA2475177A1 (en) * 2002-02-11 2003-08-21 Zymogenetics, Inc. Materials and methods for preparing dimeric growth factors
AU2003272547A1 (en) * 2002-09-16 2004-04-30 Abgenix, Inc. Method for the treatment of nephritis using anti-pdgf-dd antibodies
US20030100502A1 (en) * 2002-10-23 2003-05-29 Beals John Michael Treating musculoskeletal disorders using lp85 and analogs thereof
US20050191286A1 (en) * 2004-02-09 2005-09-01 Gandy James B. Lyophilized platelet rich plasma for the use in wound healing (chronic or acute) and bone or tissue grafts or repair
WO2005087177A2 (en) 2004-03-05 2005-09-22 Ludwig Institute For Cancer Research Chimeric anti-vegf-d antibodies and humanized anti-vegf-d antibodies and methods of using same
US7476654B2 (en) * 2004-03-08 2009-01-13 Ludwig Institute For Cancer Research Method for modulating, regulating and/or stabilizing angiogenesis
US20060142198A1 (en) * 2004-07-02 2006-06-29 Wound Care Partners Llc Compositions for treating wounds and processes for their preparation
US20060004189A1 (en) * 2004-07-02 2006-01-05 James Gandy Compositions for treating wounds and processes for their preparation
EP1885888A4 (de) * 2005-05-10 2010-05-05 Ludwig Inst Cancer Res Verfahren und zusammensetzungen zur aktivierung und hemmung von pdgf-d
ES2363758T3 (es) 2005-08-15 2011-08-16 Vegenics Pty Ltd Vegf y pdgf modificados con propiedades angiogénicas mejoradas.
PL2548578T3 (pl) 2006-05-17 2014-12-31 The Ludwig Institute For Cancer Res Kierowanie regulacją transporterów kwasów tłuszczowych przez VEGF-B, w celu modulowania ludzkich chorób
WO2010090523A1 (en) * 2009-02-06 2010-08-12 Pepscan Systems B.V. Truncated cystine-knot proteins
KR101451340B1 (ko) * 2012-08-02 2014-10-15 (주)애드바이오텍 모발 생장 촉진용 조성물
CN103469672A (zh) * 2013-09-07 2013-12-25 郴州四方立投资有限公司 一种用于造纸行业的硅灰石长纤维的制备方法
WO2017011519A1 (en) * 2015-07-13 2017-01-19 Sangamo Biosciences, Inc. Delivery methods and compositions for nuclease-mediated genome engineering
CN110590930B (zh) * 2018-06-13 2023-03-31 四川好医生攀西药业有限责任公司 美洲大蠊生长因子pdgf在制备损伤修复药物中的应用
CN111487398B (zh) * 2019-01-25 2022-11-11 四川大学华西医院 血管瘤治疗的生物标记物
CN114957439B (zh) * 2022-05-31 2023-11-28 新疆畜牧科学院生物技术研究所（新疆畜牧科学院中国-澳大利亚绵羊育种研究中心） 绵羊pdgfd、编码pdgfd核酸及其重组慢病毒、宿主细胞与应用
WO2024002271A1 (en) * 2022-06-29 2024-01-04 Tianjin University Pdgf-d prodomain and its mutant and fusion

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4228457A1 (de) * 1992-08-27 1994-04-28 Beiersdorf Ag Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen
US5585277A (en) 1993-06-21 1996-12-17 Scriptgen Pharmaceuticals, Inc. Screening method for identifying ligands for target proteins
DE69434538T2 (de) 1994-03-08 2006-08-10 Human Genome Sciences, Inc. Vaskulärer endothelialer Wachstumsfaktor 2
US5814464A (en) 1994-10-07 1998-09-29 Regeneron Pharma Nucleic acids encoding TIE-2 ligand-2
US5928939A (en) 1995-03-01 1999-07-27 Ludwig Institute For Cancer Research Vascular endothelial growth factor-b and dna coding therefor
US5607918A (en) 1995-03-01 1997-03-04 Ludwig Institute For Cancer Research Vascular endothelial growth factor-B and DNA coding therefor
CA2214439C (en) * 1995-03-02 2002-12-17 Amrad Operations Pty. Ltd. A novel growth factor and a genetic sequence encoding same
WO1996039421A1 (en) 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Human vascular endothelial growth factor 3
EP0956339B1 (de) 1996-08-23 2005-10-12 Ludwig Institute For Cancer Research Rekombinanter vaskulärer endothelzellen wachstumsfaktor d (vegf-d)
ES2432053T3 (es) * 1998-12-07 2013-11-29 Zymogenetics, Inc. Homólogo del factor del crecimiento ZVEGF3
WO2000066736A1 (en) * 1999-05-03 2000-11-09 Zymogenetics, Inc. Growth factor homolog zvegf4

Also Published As

Publication number Publication date
CA2349951A1 (en) 2000-05-18
ATE451389T1 (de) 2009-12-15
CN1325407A (zh) 2001-12-05
JP2002534061A (ja) 2002-10-15
AU1613600A (en) 2000-05-29
US6706687B1 (en) 2004-03-16
WO2000027879A1 (en) 2000-05-18
ATE556090T1 (de) 2012-05-15
EP1129110B1 (de) 2009-12-09
EP1129110A1 (de) 2001-09-05
NZ511379A (en) 2003-06-30
DK1129110T3 (da) 2010-04-06
EP2151454A3 (de) 2010-02-17
EP1129110A4 (de) 2004-08-04
EP2151454B1 (de) 2012-05-02
ES2336731T3 (es) 2010-04-15
CN1261453C (zh) 2006-06-28
EP2151454A2 (de) 2010-02-10
AU770899B2 (en) 2004-03-04

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