DE69937364T2 - Mn gen und protein - Google Patents

Mn gen und protein Download PDF

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Publication number
DE69937364T2
DE69937364T2 DE69937364T DE69937364T DE69937364T2 DE 69937364 T2 DE69937364 T2 DE 69937364T2 DE 69937364 T DE69937364 T DE 69937364T DE 69937364 T DE69937364 T DE 69937364T DE 69937364 T2 DE69937364 T2 DE 69937364T2
Authority
DE
Germany
Prior art keywords
protein
cells
seq
cell
promoter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69937364T
Other languages
German (de)
English (en)
Other versions
DE69937364D1 (de
Inventor
Jan Zavada
Silvia Pastorekova
Jaromir Pastorek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Virology
Original Assignee
Institute of Virology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/177,776 external-priority patent/US6297051B1/en
Priority claimed from US09/178,115 external-priority patent/US6297041B1/en
Application filed by Institute of Virology filed Critical Institute of Virology
Application granted granted Critical
Publication of DE69937364D1 publication Critical patent/DE69937364D1/de
Publication of DE69937364T2 publication Critical patent/DE69937364T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69937364T 1998-10-23 1999-10-22 Mn gen und protein Expired - Lifetime DE69937364T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/177,776 US6297051B1 (en) 1997-01-24 1998-10-23 MN gene and protein
US177776 1998-10-23
US09/178,115 US6297041B1 (en) 1992-03-11 1998-10-23 MN gene and protein
US178115 1998-10-23
PCT/US1999/024879 WO2000024913A2 (en) 1998-10-23 1999-10-22 Mn gene and protein

Publications (2)

Publication Number Publication Date
DE69937364D1 DE69937364D1 (de) 2007-11-29
DE69937364T2 true DE69937364T2 (de) 2008-07-17

Family

ID=26873634

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69937364T Expired - Lifetime DE69937364T2 (de) 1998-10-23 1999-10-22 Mn gen und protein

Country Status (11)

Country Link
EP (2) EP1832653A1 (enExample)
JP (3) JP3910798B2 (enExample)
AT (1) ATE376056T1 (enExample)
AU (1) AU758957C (enExample)
CA (1) CA2347649C (enExample)
CY (1) CY1107268T1 (enExample)
DE (1) DE69937364T2 (enExample)
DK (1) DK1123387T3 (enExample)
ES (1) ES2296412T3 (enExample)
NO (1) NO328884B1 (enExample)
WO (1) WO2000024913A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6902890B1 (en) 1999-11-04 2005-06-07 Diadexus, Inc. Method of diagnosing monitoring, staging, imaging and treating cancer
US20040077081A1 (en) 2001-02-07 2004-04-22 Egbert Oosterwijk Hybridoma cell line g250 and its use for producing monoclonal antibodies
AR036833A1 (es) * 2001-10-18 2004-10-06 Bayer Corp Anticuerpos humanos que se unen a mn y tienen actividad neutralizante de la adhesion celular.
US7910549B2 (en) * 2001-12-13 2011-03-22 Institute Of Virology Of The Slovak Academy Of Sciences MN gene and protein
AU2003217606C1 (en) 2002-02-21 2008-07-17 Institute Of Virology Soluble Form of Carbonic Anhydrase IX (s-CA IX), Assays to Detect s-CA IX, CA IXs Coexpression with HER-2/neu/c-erbB-2 and CA IX-Specific Monoclonal Antibodies to Non-Immunodominant Epitopes
DK2508596T3 (en) 2002-02-21 2015-10-19 Inst Virology MN / CA IX-specific monoclonal antibodies generated from MN / CA IX-poor mice, as well as methods of use.
AU2003223186A1 (en) * 2002-05-23 2004-01-23 Bayer Healthcare SOLUBLE FORM OF CARBONIC ANHYDRASE IX (s-CA IX), ASSAYS TO DETECT s-CA IX AND CA IX's COEXPRESSION WITH HER-2/neu/c-erbB-2
ATE537842T1 (de) 2002-07-01 2012-01-15 Wilex Ag Zusammesetzungen von cg250 und il-2 oder von cg250 und ifn-alpha zur krebsbehandlung des nierenzell karzinoms
EP1576010A4 (en) * 2002-08-23 2006-12-27 Chiron Corp THERAPEUTIC COMPOSITIONS AND METHODS FOR CANCER CHARACTERIZED BY EXPRESSION OF MN / CA IX ANTIGEN ASSOCIATED WITH TUMORS
EP1569633A4 (en) 2002-11-26 2008-03-05 Inst Virology CA-IX SPECIFIC HEMMER
US7524634B2 (en) * 2003-10-16 2009-04-28 Institute Of Virology, Slovak Academy Of Sciences MN/CA IX and cancer prognosis
AU2005241093B2 (en) 2004-05-04 2008-06-05 Institute Of Virology Of Slovak Academy Of Sciences MN/CA IX/ CA9 and renal cancer prognosis
US7820159B2 (en) 2006-10-31 2010-10-26 Instiute of Virology of the Slovak Academy of Sciences MN/CA IX and EGFR pathway inhibition
US8399625B1 (en) * 2009-06-25 2013-03-19 ESBATech, an Alcon Biomedical Research Unit, LLC Acceptor framework for CDR grafting
BR112015020061A8 (pt) 2013-02-22 2018-01-23 Wilex Ag composto alvo anidrase carbônica ix (caix) para tratamento de câncer, seus usos, composição farmcêutica, e método para diagnosticar, prognosticar e/ou classificar um câncer
CZ2014527A3 (cs) * 2014-08-05 2016-02-17 Ústav Organické Chemie A Biochemie Akademie Věd Čr, V.V.I. Způsob detekce aktivní formy analytů ve vzorku a stanovení schopnosti dalších látek vázat se do aktivních míst těchto analytů

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995034650A2 (en) * 1994-06-15 1995-12-21 Ciba Corning Diagnostics Corp. Mn gene and protein
US6329501B1 (en) * 1997-05-29 2001-12-11 Auburn University Methods and compositions for targeting compounds to muscle
WO1999058561A1 (fr) * 1998-05-14 1999-11-18 Pasteur Merieux Serums & Vaccins Mimotopes du virus de l'hepatite c

Also Published As

Publication number Publication date
EP1123387B1 (en) 2007-10-17
AU1132300A (en) 2000-05-15
EP1832653A1 (en) 2007-09-12
ES2296412T3 (es) 2008-04-16
AU758957B2 (en) 2003-04-03
CA2347649C (en) 2012-03-13
WO2000024913A2 (en) 2000-05-04
JP3910798B2 (ja) 2007-04-25
ATE376056T1 (de) 2007-11-15
NO328884B1 (no) 2010-06-07
NO20011926L (no) 2001-06-19
JP4488373B2 (ja) 2010-06-23
JP2007145843A (ja) 2007-06-14
DE69937364D1 (de) 2007-11-29
JP2002528085A (ja) 2002-09-03
AU758957C (en) 2004-08-12
JP4044597B2 (ja) 2008-02-06
DK1123387T3 (da) 2008-02-25
JP2008069151A (ja) 2008-03-27
WO2000024913A3 (en) 2000-09-14
CA2347649A1 (en) 2000-05-04
EP1123387A2 (en) 2001-08-16
CY1107268T1 (el) 2012-11-21
NO20011926D0 (no) 2001-04-19

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