DE69930862D1 - Expressionssysteme zur funktionellen expression von nukleinsäuren - Google Patents
Expressionssysteme zur funktionellen expression von nukleinsäurenInfo
- Publication number
- DE69930862D1 DE69930862D1 DE69930862T DE69930862T DE69930862D1 DE 69930862 D1 DE69930862 D1 DE 69930862D1 DE 69930862 T DE69930862 T DE 69930862T DE 69930862 T DE69930862 T DE 69930862T DE 69930862 D1 DE69930862 D1 DE 69930862D1
- Authority
- DE
- Germany
- Prior art keywords
- expression
- nucleic acids
- functional
- systems
- expression systems
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
- C12N15/1132—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against retroviridae, e.g. HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/121—Hammerhead
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP24475598 | 1998-08-31 | ||
JP10244755A JP2990268B1 (ja) | 1998-08-31 | 1998-08-31 | 機能性核酸転写用発現系 |
PCT/JP1999/004718 WO2000012686A1 (en) | 1998-08-31 | 1999-08-31 | Expression systems for functional nucleic acid expression |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69930862D1 true DE69930862D1 (de) | 2006-05-24 |
DE69930862T2 DE69930862T2 (de) | 2007-05-16 |
Family
ID=17123425
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69930862T Expired - Lifetime DE69930862T2 (de) | 1998-08-31 | 1999-08-31 | Expressionssysteme zur funktionellen expression von nukleinsäuren |
Country Status (5)
Country | Link |
---|---|
US (2) | US6740750B1 (de) |
EP (1) | EP1118659B1 (de) |
JP (2) | JP2990268B1 (de) |
DE (1) | DE69930862T2 (de) |
WO (1) | WO2000012686A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6995258B1 (en) | 2000-05-25 | 2006-02-07 | City Of Hope | Nucleolar targeting of therapeutics against HIV |
AU2003237303A1 (en) * | 2002-05-30 | 2003-12-19 | Albert Einstein College Of Medicine Of Yeshiva University | Aptamer constructs |
AU2004208057A1 (en) * | 2003-01-31 | 2004-08-12 | Dnavec Research Inc. | Paramyxovirus vector encoding ribozyme and utilization thereof |
ATE459707T1 (de) * | 2003-06-30 | 2010-03-15 | Dnavec Research Inc | Negativ-strang rna-virus-vektoren, welche ein gen mit veränderten hypermutierbaren regionen tragen |
US20050203047A1 (en) * | 2004-03-10 | 2005-09-15 | Ulrich Thomann | Delivery vectors for short interfering RNA, micro-RNA and antisense RNA |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5792608A (en) * | 1991-12-12 | 1998-08-11 | Gilead Sciences, Inc. | Nuclease stable and binding competent oligomers and methods for their use |
DE69333937T2 (de) | 1992-06-29 | 2006-08-31 | Gene Shears Pty. Ltd. | Nukleinsäuren und sie verwendende verfahren zur bekämpfung viraler pathogene |
WO1994008033A1 (en) * | 1992-10-02 | 1994-04-14 | The Board Of Trustees Of The Leland Stanford Junior University | tRNA GENES TO STABILIZE UNSTABLE PLASMID INHERITANCE IN GROWING CELLS |
EP0702716A4 (de) | 1993-05-17 | 1999-05-26 | Univ California | Gentherapy bei hiv-infektion und aids mit hilfe von ribozymen |
DE69535752D1 (de) * | 1994-04-13 | 2008-06-26 | Biotransplant Inc | Alpha(1,3)galactosyltransferase-negatives schwein |
US20020058636A1 (en) * | 1994-09-21 | 2002-05-16 | Geoffrey P. Symonds | Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs |
US6132989A (en) * | 1996-06-03 | 2000-10-17 | University Of Washington | Methods and compositions for enhanced stability of non-adenoviral DNA |
-
1998
- 1998-08-31 JP JP10244755A patent/JP2990268B1/ja not_active Expired - Lifetime
-
1999
- 1999-08-31 US US09/763,590 patent/US6740750B1/en not_active Expired - Fee Related
- 1999-08-31 JP JP2000567673A patent/JP3829176B2/ja not_active Expired - Lifetime
- 1999-08-31 DE DE69930862T patent/DE69930862T2/de not_active Expired - Lifetime
- 1999-08-31 WO PCT/JP1999/004718 patent/WO2000012686A1/ja active IP Right Grant
- 1999-08-31 EP EP99940588A patent/EP1118659B1/de not_active Expired - Lifetime
-
2004
- 2004-04-09 US US10/820,820 patent/US20040198689A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP3829176B2 (ja) | 2006-10-04 |
EP1118659A1 (de) | 2001-07-25 |
US20040198689A1 (en) | 2004-10-07 |
DE69930862T2 (de) | 2007-05-16 |
EP1118659B1 (de) | 2006-04-12 |
WO2000012686A1 (en) | 2000-03-09 |
EP1118659A4 (de) | 2002-12-04 |
JP2990268B1 (ja) | 1999-12-13 |
JP2000069972A (ja) | 2000-03-07 |
US6740750B1 (en) | 2004-05-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |