DE69929051T2 - Lanthanidchelate der cinoxacin und ihre verwendung als biomolekulare probe - Google Patents
Lanthanidchelate der cinoxacin und ihre verwendung als biomolekulare probe Download PDFInfo
- Publication number
- DE69929051T2 DE69929051T2 DE69929051T DE69929051T DE69929051T2 DE 69929051 T2 DE69929051 T2 DE 69929051T2 DE 69929051 T DE69929051 T DE 69929051T DE 69929051 T DE69929051 T DE 69929051T DE 69929051 T2 DE69929051 T2 DE 69929051T2
- Authority
- DE
- Germany
- Prior art keywords
- group
- cinoxacin
- minutes
- lanthanide
- hplc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 CCN(c(c1c2)cc3c2OCO3)N(C)C(C(NCCNC(CN(CCN(CCN(CC(N[C@](*)CCCCNC(CI)=O)=O)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)C1=O Chemical compound CCN(c(c1c2)cc3c2OCO3)N(C)C(C(NCCNC(CN(CCN(CCN(CC(N[C@](*)CCCCNC(CI)=O)=O)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)C1=O 0.000 description 2
- MRNRUKCZWNOTBZ-UHFFFAOYSA-N CCN(c(c1c2)cc3c2OCO3)N=C(C(NCCNC(CN(CCN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)C1=O Chemical compound CCN(c(c1c2)cc3c2OCO3)N=C(C(NCCNC(CN(CCN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)C1=O MRNRUKCZWNOTBZ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/76—Metal complexes of amino carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/83—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of an acyclic saturated carbon skeleton
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9813776.3A GB9813776D0 (en) | 1998-06-25 | 1998-06-25 | Novel compounds |
| GB9813776 | 1998-06-25 | ||
| PCT/EP1999/004277 WO1999066780A2 (en) | 1998-06-25 | 1999-06-18 | Cinoxacin lanthanide chelates and their use as biomolecular probes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69929051D1 DE69929051D1 (de) | 2006-01-26 |
| DE69929051T2 true DE69929051T2 (de) | 2006-07-13 |
Family
ID=10834399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69929051T Expired - Fee Related DE69929051T2 (de) | 1998-06-25 | 1999-06-18 | Lanthanidchelate der cinoxacin und ihre verwendung als biomolekulare probe |
Country Status (8)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6740756B1 (en) | 1998-07-07 | 2004-05-25 | Smithkline Beecham Corporation | Fluorescent lanthanide chelates |
| WO2000001663A1 (en) * | 1998-07-07 | 2000-01-13 | Smithkline Beecham Corporation | Novel fluorescent lanthanide chelates |
| AUPP856399A0 (en) * | 1999-02-08 | 1999-03-04 | Australian Membrane And Biotechnology Research Institute | Improved compounds for protein binding |
| JP2006022123A (ja) * | 2002-06-27 | 2006-01-26 | Ajinomoto Co Inc | キレート剤 |
| CN107954893A (zh) * | 2017-11-28 | 2018-04-24 | 兰州纬寰生物科技有限公司 | 邻氨基苯甲酰胺衍生物及制备方法和用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE207098C (de) | 1908-03-06 | 1909-02-16 | Koppers Gmbh Heinrich | Verfahren zur Leuchtgasherstellung durch Destillation von Steinkohlen und Beimengung eines billigeren Gases zu dem Steinkohlengas. |
| NL147145B (nl) * | 1969-02-04 | 1975-09-15 | Lilly Co Eli | Werkwijze ter bereiding van preparaten met antimicrobiele werking. |
| US4379929A (en) * | 1981-03-19 | 1983-04-12 | Eli Lilly And Company | 4(1H)-Oxocinnoline-3-carboxylic acid derivatives |
| DD207098A3 (de) * | 1981-12-22 | 1984-02-15 | Schmidt Hans Joerg | Verfahren zur herstellung von 1-alkyl-6,7-methylendioxy-4(1h)-oxo-cinnolin-3-carbonsaeuren |
| ES2133312T3 (es) | 1991-12-05 | 1999-09-16 | Wallac Oy | Quelatos de lantanidos luminiscentes. |
| US5622821A (en) * | 1994-06-29 | 1997-04-22 | The Regents Of The University Of California | Luminescent lanthanide chelates and methods of use |
-
1998
- 1998-06-25 GB GBGB9813776.3A patent/GB9813776D0/en not_active Ceased
-
1999
- 1999-06-18 JP JP2000555481A patent/JP2002518413A/ja active Pending
- 1999-06-18 US US09/720,172 patent/US6441167B1/en not_active Expired - Fee Related
- 1999-06-18 ES ES99931117T patent/ES2253899T3/es not_active Expired - Lifetime
- 1999-06-18 CA CA002335610A patent/CA2335610A1/en not_active Abandoned
- 1999-06-18 DE DE69929051T patent/DE69929051T2/de not_active Expired - Fee Related
- 1999-06-18 EP EP99931117A patent/EP1090007B1/en not_active Expired - Lifetime
- 1999-06-18 WO PCT/EP1999/004277 patent/WO1999066780A2/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2335610A1 (en) | 1999-12-29 |
| WO1999066780A3 (en) | 2000-02-03 |
| JP2002518413A (ja) | 2002-06-25 |
| US6441167B1 (en) | 2002-08-27 |
| ES2253899T3 (es) | 2006-06-01 |
| EP1090007B1 (en) | 2005-12-21 |
| EP1090007A2 (en) | 2001-04-11 |
| DE69929051D1 (de) | 2006-01-26 |
| WO1999066780A2 (en) | 1999-12-29 |
| GB9813776D0 (en) | 1998-08-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |