DE69920748D1 - Pseudopeptide mit inhibierender wirkung auf protein-tyrosinkinasen und sie enthaltende pharmazeutische zusammensetzungen - Google Patents

Pseudopeptide mit inhibierender wirkung auf protein-tyrosinkinasen und sie enthaltende pharmazeutische zusammensetzungen

Info

Publication number
DE69920748D1
DE69920748D1 DE69920748T DE69920748T DE69920748D1 DE 69920748 D1 DE69920748 D1 DE 69920748D1 DE 69920748 T DE69920748 T DE 69920748T DE 69920748 T DE69920748 T DE 69920748T DE 69920748 D1 DE69920748 D1 DE 69920748D1
Authority
DE
Germany
Prior art keywords
tyrosinkinases
pseudopeptides
protein
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69920748T
Other languages
English (en)
Inventor
Christiane Garbay
Wang-Qing Liu
Michel Vidal
P Roques
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of DE69920748D1 publication Critical patent/DE69920748D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DE69920748T 1998-12-24 1999-12-24 Pseudopeptide mit inhibierender wirkung auf protein-tyrosinkinasen und sie enthaltende pharmazeutische zusammensetzungen Expired - Lifetime DE69920748D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9816459A FR2787793B1 (fr) 1998-12-24 1998-12-24 Composes pseudopeptidiques dotes d'une activite inhibitrice a l'egard des voies activees par les proteines a activite tyrosine kinase et les compositions pharmaceutiques les contenant
PCT/FR1999/003289 WO2000039153A1 (fr) 1998-12-24 1999-12-24 Composes pseudopeptidiques dotes d'une activite inhibitrice a l'egard des voies activees par les proteines a activite tyrosine kinase et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
DE69920748D1 true DE69920748D1 (de) 2004-11-04

Family

ID=9534521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69920748T Expired - Lifetime DE69920748D1 (de) 1998-12-24 1999-12-24 Pseudopeptide mit inhibierender wirkung auf protein-tyrosinkinasen und sie enthaltende pharmazeutische zusammensetzungen

Country Status (6)

Country Link
EP (1) EP1140980B1 (de)
AT (1) ATE277942T1 (de)
CA (1) CA2356777A1 (de)
DE (1) DE69920748D1 (de)
FR (1) FR2787793B1 (de)
WO (1) WO2000039153A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19933492B4 (de) 1999-07-16 2008-01-10 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Konjugat zur Vermittlung eines zell-, kompartiment- oder membranspezifischen Transports von Wirksubstanzen, Verfahren zu dessen Herstellung und dessen Verwendung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6184205B1 (en) * 1994-07-22 2001-02-06 University Of North Carolina At Chapel Hill GRB2 SH3 binding peptides and methods of isolating and using same
US6280964B1 (en) * 1995-04-14 2001-08-28 The Regents Of The University Of California Binding sites for phosphotyrosine binding domains
GB9603227D0 (en) * 1996-02-15 1996-04-17 Pharmacia Spa Peptide antagonists of cellular mitogenesis and motogenesis and their therapeutic use

Also Published As

Publication number Publication date
FR2787793B1 (fr) 2001-03-23
ATE277942T1 (de) 2004-10-15
EP1140980B1 (de) 2004-09-29
EP1140980A1 (de) 2001-10-10
CA2356777A1 (fr) 2000-07-06
WO2000039153A1 (fr) 2000-07-06
FR2787793A1 (fr) 2000-06-30

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