DE69919554D1 - SYSTEMS FOR THE DELIVERY OF MEDICINAL PRODUCTS TO Mucous Membranes - Google Patents

SYSTEMS FOR THE DELIVERY OF MEDICINAL PRODUCTS TO Mucous Membranes

Info

Publication number
DE69919554D1
DE69919554D1 DE69919554T DE69919554T DE69919554D1 DE 69919554 D1 DE69919554 D1 DE 69919554D1 DE 69919554 T DE69919554 T DE 69919554T DE 69919554 T DE69919554 T DE 69919554T DE 69919554 D1 DE69919554 D1 DE 69919554D1
Authority
DE
Germany
Prior art keywords
delivery
systems
mucous membranes
medicinal products
mucosal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69919554T
Other languages
German (de)
Other versions
DE69919554T2 (en
Inventor
J Matson
Yen-Lane Chen
T Ruth
R Benes
G Burgaud
L Horriere
M Seyler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Innovative Properties Co
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Application granted granted Critical
Publication of DE69919554D1 publication Critical patent/DE69919554D1/en
Publication of DE69919554T2 publication Critical patent/DE69919554T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids

Abstract

The present invention is directed to mucosal originated drug delivery systems and methods for using the drug delivery system to treat conditions in animals. Conditions amenable to treatment according to the invention are also described. The described mucosal drug delivery systems provide for drug release across a mucosal membrane as well as release away from the mucosal membrane.
DE69919554T 1998-10-02 1999-10-01 SYSTEMS FOR DRUG DISPOSAL OF MICE Expired - Fee Related DE69919554T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10295698P 1998-10-02 1998-10-02
US102956P 1998-10-02
PCT/US1999/022967 WO2000019987A1 (en) 1998-10-02 1999-10-01 Mucosal originated drug delivery systems and animal applications

Publications (2)

Publication Number Publication Date
DE69919554D1 true DE69919554D1 (en) 2004-09-23
DE69919554T2 DE69919554T2 (en) 2005-09-01

Family

ID=22292601

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69919554T Expired - Fee Related DE69919554T2 (en) 1998-10-02 1999-10-01 SYSTEMS FOR DRUG DISPOSAL OF MICE

Country Status (19)

Country Link
EP (1) EP1117390B1 (en)
JP (1) JP2002526403A (en)
KR (1) KR20010075528A (en)
CN (1) CN1321086A (en)
AT (1) ATE273698T1 (en)
AU (1) AU768040B2 (en)
BR (1) BR9915020A (en)
CA (1) CA2345808A1 (en)
CZ (1) CZ20011188A3 (en)
DE (1) DE69919554T2 (en)
ES (1) ES2228125T3 (en)
HU (1) HUP0103543A2 (en)
IL (1) IL142168A0 (en)
MX (1) MXPA01003310A (en)
NO (1) NO20011656D0 (en)
NZ (1) NZ510771A (en)
PL (1) PL347061A1 (en)
PT (1) PT1117390E (en)
WO (1) WO2000019987A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331539B1 (en) 1999-06-10 2001-12-18 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines
DE10107659B4 (en) * 2001-02-19 2008-03-13 Lts Lohmann Therapie-Systeme Ag Mucoadhesive disintegratable drug preparation for drug administration in veterinary and human medicine
JP5043435B2 (en) 2003-10-03 2012-10-10 スリーエム イノベイティブ プロパティズ カンパニー Alkoxy substituted imidazoquinolines
AR046781A1 (en) 2003-11-25 2005-12-21 3M Innovative Properties Co IMIDAZOQUINOLINE DERIVATIVES. PHARMACEUTICAL COMPOSITIONS.
FI20041425A0 (en) * 2004-11-05 2004-11-05 Orion Corp Transmucosal veterinary composition
WO2006084251A2 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
JP2006335640A (en) * 2005-05-06 2006-12-14 Daicho Kikaku:Kk Drug for animal
KR101464003B1 (en) * 2005-07-29 2014-11-20 산텐 세이야꾸 가부시키가이샤 Non-invasive drug delivery system targeting posterior eye tissue using solid composition
JP2009528900A (en) * 2006-03-07 2009-08-13 オラヘルス コーポレーション Medical multilayer patch with impermeable center
KR101230804B1 (en) * 2006-07-21 2013-02-08 바이오딜리버리 사이언시스 인터내셔널 인코포레이티드 Transmucosal delivery devices with enhanced uptake
DE202008017304U1 (en) 2008-02-29 2009-08-27 Acino Ag Oral decaying film for the therapeutic use of antiparasitic agents in animals
EP2429521B1 (en) * 2009-05-15 2017-10-18 Recro Pharma, Inc. Sublingual dexmedetomidine compositions and methods of use thereof
CN102655878A (en) * 2009-07-17 2012-09-05 俄克拉荷马州大学评议会 Supralingual vaccines and applicators
EP2570217B1 (en) 2011-09-15 2014-11-05 Klingelnberg AG Semi-completing skiving method and device with skiving tool for performing a semi-completing skiving method
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
CN106456561B (en) 2013-10-07 2020-02-28 帝国制药美国公司 Methods and compositions for treating attention deficit hyperactivity disorder, anxiety disorders, and insomnia using dexmedetomidine transdermal compositions
JP6188933B2 (en) 2013-10-07 2017-08-30 テイコク ファーマ ユーエスエー インコーポレーテッド Methods and compositions for transdermal delivery of non-sedating amounts of dexmedetomidine
EP3054931B1 (en) * 2013-10-07 2020-12-23 Teikoku Pharma USA, Inc. Transdermal delivery device for managing pain comprising dexmedetomidine transdermal compositions
CA2924231C (en) 2013-10-07 2018-04-03 Teikoku Pharma Usa, Inc. Dexmedetomidine transdermal delivery devices and methods for using the same
EP3054934A4 (en) * 2013-10-07 2017-04-05 Teikoku Pharma USA, Inc. Methods and compositions for treating withdrawal syndromes using non-sedative dexmedetomidine transdermal compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB981372A (en) * 1960-05-04 1965-01-27 Pfizer Ltd Pharmaceutical formulations for oral administration to animals
GB1455251A (en) * 1972-08-25 1976-11-10 Evode Ltd Method of sealing gaps and compositions therefor heat
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5346701A (en) * 1993-02-22 1994-09-13 Theratech, Inc. Transmucosal delivery of macromolecular drugs
FR2712807B1 (en) * 1993-11-24 1996-02-23 Vetoquinol Sa Solid mucoadhesive, therapeutic or hygienic composition, for administration by application to the oral or nasal mucosa.
US5688520A (en) * 1995-03-29 1997-11-18 Minnesota Mining And Manufacturing Company Transmucosal delivery of melatonin for prevention of migraine

Also Published As

Publication number Publication date
PL347061A1 (en) 2002-03-11
IL142168A0 (en) 2002-03-10
WO2000019987A1 (en) 2000-04-13
EP1117390B1 (en) 2004-08-18
PT1117390E (en) 2005-01-31
CA2345808A1 (en) 2000-04-13
ES2228125T3 (en) 2005-04-01
NZ510771A (en) 2003-08-29
HUP0103543A2 (en) 2002-01-28
DE69919554T2 (en) 2005-09-01
MXPA01003310A (en) 2003-05-15
NO20011656L (en) 2001-04-02
JP2002526403A (en) 2002-08-20
CN1321086A (en) 2001-11-07
AU1100100A (en) 2000-04-26
BR9915020A (en) 2001-08-14
CZ20011188A3 (en) 2001-08-15
NO20011656D0 (en) 2001-04-02
KR20010075528A (en) 2001-08-09
EP1117390A1 (en) 2001-07-25
AU768040B2 (en) 2003-11-27
ATE273698T1 (en) 2004-09-15

Similar Documents

Publication Publication Date Title
DE69919554D1 (en) SYSTEMS FOR THE DELIVERY OF MEDICINAL PRODUCTS TO Mucous Membranes
ATE429922T1 (en) TOPICAL GEL DELIVERY SYSTEMS FOR THE TREATMENT OF SKIN DISEASES
ATE211907T1 (en) OSMOTIC DRUG RELEASE SYSTEM
GEP20053602B (en) Aripiprazole for Oral Administration
ATE237330T1 (en) ADMINISTRATION OF NICOTINE IN THE COLON FOR THE TREATMENT OF INFLAMMATORY VITAL DISEASE
HK1096857A1 (en) Medicamentously targeted local lipolysis
DE60122672D1 (en) COMPOSITION FOR INTESTINAL ADMINISTRATION
DE69624355D1 (en) METHOD FOR THE DELIVERY OF MEDICINAL PRODUCTS BY MEANS OF GENTHERAPY
DK1082131T3 (en) Immunoregulator
ATE241338T1 (en) DRUG DELIVERY SYSTEM, IN PARTICULAR FOR ADMINISTRATION OF ANDROGENS
DE60026491D1 (en) MELAGATRAN FOR THE TREATMENT OF INFLAMMATION
DE59608150D1 (en) TRANSDERMAL THERAPEUTIC SYSTEM (TTS) FOR THE ADMINISTRATION OF TESTOSTERONE
CA2285477A1 (en) Formulations and methods to treat and prevent equine protozoal myeloencephalitis
DE69929616D1 (en) OXYHUMIC ACID AND ITS USE FOR THE TREATMENT OF DIFFERENT DISORDER
MX9803610A (en) Use of flupirtin for the prevention and treatment of diseases which are associated with damage to the haemopoietic cell system.
DE60039579D1 (en) HUMANE ADULTE ASTROCYTES, AND THEIR PREPARATION AND USE
ATE261724T1 (en) ANTICONVULSIVE DERIVATIVES FOR THE TREATMENT OF POST-TRAAUMATIC STRESS DISEASES
UA31156A (en) METHOD OF TREATMENT OF PULMONTERTERITS OF CALVES
AU2396900A (en) Treatment and prevention of hiv and other viral infections
DE9405351U1 (en) Device for the production of transdermal therapeutic systems
FR2783396B1 (en) DEVICE FOR SLOW DELIVERY OF TREATMENT PRODUCTS, ESPECIALLY PHYTOSANITARY
RU94020597A (en) Method of pseudotuberculosis treatment
UA29004A (en) The method for treatment of sepsis
UA31271A (en) Method for preparing patients with intestinal fistulas for surgery
UA27148C2 (en) Method for treating acute pyelonephritis

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee