DE69917476D1 - Methode zur verbindung einer kapillare mit einer mikrofluidvorrichtung - Google Patents
Methode zur verbindung einer kapillare mit einer mikrofluidvorrichtungInfo
- Publication number
- DE69917476D1 DE69917476D1 DE69917476T DE69917476T DE69917476D1 DE 69917476 D1 DE69917476 D1 DE 69917476D1 DE 69917476 T DE69917476 T DE 69917476T DE 69917476 T DE69917476 T DE 69917476T DE 69917476 D1 DE69917476 D1 DE 69917476D1
- Authority
- DE
- Germany
- Prior art keywords
- capillary
- hole
- capillary tube
- edge surface
- flat bottom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44791—Microapparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/12—Specific details about manufacturing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B01L2300/0838—Capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0421—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6034—Construction of the column joining multiple columns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
- G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
- G01N30/724—Nebulising, aerosol formation or ionisation
- G01N30/7266—Nebulising, aerosol formation or ionisation by electric field, e.g. electrospray
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
- Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Electrochemistry (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Electron Tubes For Measurement (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/169,146 US6605472B1 (en) | 1998-10-09 | 1998-10-09 | Microfluidic devices connected to glass capillaries with minimal dead volume |
PCT/CA1999/000868 WO2000022409A2 (en) | 1998-10-09 | 1999-09-23 | Microfluidic devices connected to capillaries with minimal dead volume |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69917476D1 true DE69917476D1 (de) | 2004-06-24 |
DE69917476T2 DE69917476T2 (de) | 2004-10-07 |
Family
ID=22614404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69917476T Expired - Fee Related DE69917476T2 (de) | 1998-10-09 | 1999-09-23 | Methode zur verbindung einer kapillare mit einer mikrofluidvorrichtung |
Country Status (6)
Country | Link |
---|---|
US (2) | US6605472B1 (de) |
EP (1) | EP1127258B1 (de) |
AT (1) | ATE267393T1 (de) |
CA (1) | CA2386056A1 (de) |
DE (1) | DE69917476T2 (de) |
WO (1) | WO2000022409A2 (de) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001061338A1 (en) * | 2000-02-18 | 2001-08-23 | Evotec Oai Ag | An end element for capillaries or chip channels |
WO2002030486A2 (en) * | 2000-10-13 | 2002-04-18 | Fluidigm Corporation | Microfluidic device based sample injection system for analytical devices |
DE10154601B4 (de) * | 2000-11-13 | 2007-02-22 | Agilent Technologies, Inc. (n.d.Ges.d.Staates Delaware), Palo Alto | Ein Mikrobauelement mit einem integrierten hervorstehenden Elektrospray-Emitter und ein Verfahren zum Herstellen des Mikrobauelements |
AU2002306486A1 (en) * | 2001-02-09 | 2002-08-28 | Microchem Solutions | Method and apparatus for sample injection in microfabricated devices |
AU2002307152A1 (en) | 2001-04-06 | 2002-10-21 | California Institute Of Technology | Nucleic acid amplification utilizing microfluidic devices |
DE50105368D1 (de) * | 2001-06-28 | 2005-03-24 | Agilent Technologies Inc | Mikrofluid-System mit Regler |
US6803568B2 (en) * | 2001-09-19 | 2004-10-12 | Predicant Biosciences, Inc. | Multi-channel microfluidic chip for electrospray ionization |
US8440093B1 (en) | 2001-10-26 | 2013-05-14 | Fuidigm Corporation | Methods and devices for electronic and magnetic sensing of the contents of microfluidic flow channels |
US7691333B2 (en) | 2001-11-30 | 2010-04-06 | Fluidigm Corporation | Microfluidic device and methods of using same |
EP2360234B1 (de) | 2001-11-30 | 2015-07-22 | Fluidigm Corporation | Mikrofluide Vorrichtung und Verfahren seiner Verwendung |
US7105810B2 (en) * | 2001-12-21 | 2006-09-12 | Cornell Research Foundation, Inc. | Electrospray emitter for microfluidic channel |
DE10213390C1 (de) * | 2002-03-26 | 2003-08-14 | Bruker Daltonik Gmbh | Kopplung Kapillarelektrophorese (CE) mit Massenspektrometrie (MS) unter Bewahrung bester Separation |
AU2003224817B2 (en) | 2002-04-01 | 2008-11-06 | Fluidigm Corporation | Microfluidic particle-analysis systems |
AU2003282875A1 (en) | 2002-09-25 | 2004-04-19 | California Institute Of Technology | Microfluidic large scale integration |
WO2004040001A2 (en) | 2002-10-02 | 2004-05-13 | California Institute Of Technology | Microfluidic nucleic acid analysis |
AU2003900329A0 (en) * | 2003-01-24 | 2003-02-13 | Microtechnology Centre Management Limited | Microfluidic connector |
US7666361B2 (en) | 2003-04-03 | 2010-02-23 | Fluidigm Corporation | Microfluidic devices and methods of using same |
US7476363B2 (en) | 2003-04-03 | 2009-01-13 | Fluidigm Corporation | Microfluidic devices and methods of using same |
US8828663B2 (en) | 2005-03-18 | 2014-09-09 | Fluidigm Corporation | Thermal reaction device and method for using the same |
US7604965B2 (en) | 2003-04-03 | 2009-10-20 | Fluidigm Corporation | Thermal reaction device and method for using the same |
US20050145496A1 (en) | 2003-04-03 | 2005-07-07 | Federico Goodsaid | Thermal reaction device and method for using the same |
US7007710B2 (en) | 2003-04-21 | 2006-03-07 | Predicant Biosciences, Inc. | Microfluidic devices and methods |
US7413712B2 (en) | 2003-08-11 | 2008-08-19 | California Institute Of Technology | Microfluidic rotary flow reactor matrix |
US7537807B2 (en) | 2003-09-26 | 2009-05-26 | Cornell University | Scanned source oriented nanofiber formation |
US7282705B2 (en) | 2003-12-19 | 2007-10-16 | Agilent Technologies, Inc. | Microdevice having an annular lining for producing an electrospray emitter |
AU2005231431B2 (en) * | 2004-04-02 | 2011-02-10 | Eksigent Technologies Llc | Microfluidic connections |
US20060022130A1 (en) * | 2004-07-29 | 2006-02-02 | Predicant Biosciences, Inc., A Delaware Corporation | Microfluidic devices and methods with integrated electrical contact |
US7591883B2 (en) * | 2004-09-27 | 2009-09-22 | Cornell Research Foundation, Inc. | Microfiber supported nanofiber membrane |
US20060166347A1 (en) * | 2005-01-27 | 2006-07-27 | Applera Corporation | Sample preparation devices and methods |
JP2007043042A (ja) * | 2005-07-07 | 2007-02-15 | Sumitomo Electric Ind Ltd | ウェハ保持体およびその製造方法、ならびにそれを搭載したウェハプローバ及び半導体加熱装置 |
DE102005032983B4 (de) * | 2005-07-14 | 2007-05-31 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Düsenanordnung |
US8794929B2 (en) | 2005-11-23 | 2014-08-05 | Eksigent Technologies Llc | Electrokinetic pump designs and drug delivery systems |
US20070170056A1 (en) * | 2006-01-26 | 2007-07-26 | Arnold Don W | Microscale electrochemical cell and methods incorporating the cell |
US8647590B2 (en) * | 2006-03-16 | 2014-02-11 | Agilent Technologies, Inc. | Optical detection cell with micro-fluidic chip |
US20070218454A1 (en) * | 2006-03-16 | 2007-09-20 | Brennen Reid A | Optical detection cell for micro-fluidics |
US7629124B2 (en) * | 2006-06-30 | 2009-12-08 | Canon U.S. Life Sciences, Inc. | Real-time PCR in micro-channels |
US20080182136A1 (en) * | 2007-01-26 | 2008-07-31 | Arnold Don W | Microscale Electrochemical Cell And Methods Incorporating The Cell |
US7867592B2 (en) | 2007-01-30 | 2011-01-11 | Eksigent Technologies, Inc. | Methods, compositions and devices, including electroosmotic pumps, comprising coated porous surfaces |
AU2008236739B2 (en) | 2007-04-04 | 2014-05-29 | Ande Corporation | Plastic microfluidic separation and detection platforms |
US8251672B2 (en) | 2007-12-11 | 2012-08-28 | Eksigent Technologies, Llc | Electrokinetic pump with fixed stroke volume |
CN101738449B (zh) * | 2008-11-07 | 2011-08-31 | 中国科学院大连化学物理研究所 | 一种电极支架及其在微流控芯片系统中的应用 |
US20100199750A1 (en) | 2009-02-06 | 2010-08-12 | Arnold Don W | Microfludic Analysis System and Method |
JP2012529908A (ja) | 2009-06-15 | 2012-11-29 | ネットバイオ・インコーポレーテッド | 法医学的dnaの定量化のための改善された方法 |
US8951471B2 (en) * | 2010-02-26 | 2015-02-10 | Perkinelmer Health Sciences, Inc. | Jet assembly for use in detectors and other devices |
CN101823686B (zh) * | 2010-04-21 | 2012-07-04 | 大连理工大学 | 一种热塑性聚合物多层微流控芯片封合方法 |
GB201011019D0 (en) | 2010-07-01 | 2010-08-18 | Weston Richard | Ionisation mass spectrometry |
US20150137015A1 (en) * | 2012-07-12 | 2015-05-21 | Agency For Science, Technology And Research | Connector for microfluidic device, a method for injecting fluid into microfluidic device using the connector and a method of providing and operating a valve |
US9453996B2 (en) | 2013-10-23 | 2016-09-27 | Tokitae Llc | Devices and methods for staining and microscopy |
DE102015120860B4 (de) * | 2014-12-02 | 2022-10-20 | Micromass Uk Limited | Ringförmige Gegenelektrode zum Verbessern der Strahlstabilität und der Verbindungsempfindlichkeit auf einer Mikrofluidikvorrichtung vom Keramikkacheltyp |
US10258741B2 (en) | 2016-12-28 | 2019-04-16 | Cequr Sa | Microfluidic flow restrictor and system |
CN113797986B (zh) | 2021-10-11 | 2023-05-26 | 苏州美翎生物医学科技有限公司 | 一种可微调毛细管同轴排列的微流控芯片 |
CN114870917B (zh) * | 2022-05-09 | 2023-06-06 | 南京大学 | 用于识别不同细胞的微流控芯片及其制备方法和检测平台 |
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US4920366A (en) | 1989-05-31 | 1990-04-24 | Amp Incorporated | Construction of an optical fiber with a connector |
EP0617278A1 (de) | 1993-03-12 | 1994-09-28 | Orion Research, Incorporated | Kapillarverbindungen zur Anwendung bei Trennverfahren |
US5540464A (en) * | 1994-10-04 | 1996-07-30 | J&W Scientific Incorporated | Capillary connector |
US5872010A (en) | 1995-07-21 | 1999-02-16 | Northeastern University | Microscale fluid handling system |
US5779868A (en) * | 1996-06-28 | 1998-07-14 | Caliper Technologies Corporation | Electropipettor and compensation means for electrophoretic bias |
WO1998010122A1 (en) * | 1996-09-03 | 1998-03-12 | Northeastern University | Microfabricated hybrid capillary array and multichannel detection assembly |
US5969353A (en) * | 1998-01-22 | 1999-10-19 | Millennium Pharmaceuticals, Inc. | Microfluid chip mass spectrometer interface |
-
1998
- 1998-10-09 US US09/169,146 patent/US6605472B1/en not_active Expired - Fee Related
-
1999
- 1999-09-23 DE DE69917476T patent/DE69917476T2/de not_active Expired - Fee Related
- 1999-09-23 AT AT99944204T patent/ATE267393T1/de not_active IP Right Cessation
- 1999-09-23 CA CA002386056A patent/CA2386056A1/en not_active Abandoned
- 1999-09-23 EP EP99944204A patent/EP1127258B1/de not_active Expired - Lifetime
- 1999-09-23 WO PCT/CA1999/000868 patent/WO2000022409A2/en active IP Right Grant
-
2003
- 2003-06-19 US US10/464,657 patent/US20030211631A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20030211631A1 (en) | 2003-11-13 |
EP1127258A2 (de) | 2001-08-29 |
CA2386056A1 (en) | 2000-04-20 |
WO2000022409A3 (en) | 2000-07-13 |
WO2000022409A2 (en) | 2000-04-20 |
ATE267393T1 (de) | 2004-06-15 |
EP1127258B1 (de) | 2004-05-19 |
US6605472B1 (en) | 2003-08-12 |
DE69917476T2 (de) | 2004-10-07 |
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