DE69903627D1 - Tetrahydroisochinolinderivate als modulatoren von dopamin d3 rezeptoren - Google Patents
Tetrahydroisochinolinderivate als modulatoren von dopamin d3 rezeptorenInfo
- Publication number
- DE69903627D1 DE69903627D1 DE69903627T DE69903627T DE69903627D1 DE 69903627 D1 DE69903627 D1 DE 69903627D1 DE 69903627 T DE69903627 T DE 69903627T DE 69903627 T DE69903627 T DE 69903627T DE 69903627 D1 DE69903627 D1 DE 69903627D1
- Authority
- DE
- Germany
- Prior art keywords
- tetrahydroisochinoline
- dopamine
- modulators
- receptors
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9812522.2A GB9812522D0 (en) | 1998-06-10 | 1998-06-10 | Compounds |
PCT/EP1999/003840 WO1999064412A1 (en) | 1998-06-10 | 1999-06-01 | Tetrahydroisoquinoline derivatives as modulators of dopamine d3 receptors |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69903627D1 true DE69903627D1 (de) | 2002-11-28 |
DE69903627T2 DE69903627T2 (de) | 2003-06-26 |
Family
ID=10833528
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69903627T Expired - Fee Related DE69903627T2 (de) | 1998-06-10 | 1999-06-01 | Tetrahydroisochinolinderivate als modulatoren von dopamin d3 rezeptoren |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1086095B1 (de) |
JP (1) | JP2002517493A (de) |
CA (1) | CA2334814A1 (de) |
DE (1) | DE69903627T2 (de) |
ES (1) | ES2186365T3 (de) |
GB (1) | GB9812522D0 (de) |
WO (1) | WO1999064412A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
GB0221443D0 (en) | 2002-09-16 | 2002-10-23 | Glaxo Group Ltd | Pyridine derivates |
JP7015092B2 (ja) | 2016-07-28 | 2022-02-02 | 塩野義製薬株式会社 | ドーパミンd3受容体拮抗作用を有する含窒素縮環化合物 |
JPWO2019146739A1 (ja) * | 2018-01-26 | 2021-01-07 | 塩野義製薬株式会社 | ドーパミンd3受容体拮抗作用を有する縮環化合物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9709220A (pt) * | 1996-05-11 | 1999-08-10 | Smithkline Beecham Plc | Derivados de tetra-hidro-isoquinolina como moduladores dos receptores D3 da dopamina |
TR199902724T2 (xx) * | 1997-05-03 | 2000-04-21 | Smithkline Beecham P.L.C. | Dopamine D3 resept�rleri mod�lat�rleri olarak tetrahidroisokuinolin t�revleri. |
GB9709303D0 (en) * | 1997-05-09 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
-
1998
- 1998-06-10 GB GBGB9812522.2A patent/GB9812522D0/en not_active Ceased
-
1999
- 1999-06-01 CA CA002334814A patent/CA2334814A1/en not_active Abandoned
- 1999-06-01 DE DE69903627T patent/DE69903627T2/de not_active Expired - Fee Related
- 1999-06-01 JP JP2000553421A patent/JP2002517493A/ja active Pending
- 1999-06-01 WO PCT/EP1999/003840 patent/WO1999064412A1/en active IP Right Grant
- 1999-06-01 ES ES99926510T patent/ES2186365T3/es not_active Expired - Lifetime
- 1999-06-01 EP EP99926510A patent/EP1086095B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1086095B1 (de) | 2002-10-23 |
EP1086095A1 (de) | 2001-03-28 |
WO1999064412A1 (en) | 1999-12-16 |
DE69903627T2 (de) | 2003-06-26 |
CA2334814A1 (en) | 1999-12-16 |
GB9812522D0 (en) | 1998-08-05 |
ES2186365T3 (es) | 2003-05-01 |
JP2002517493A (ja) | 2002-06-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |