DE69902852T2 - Implantat enthaltend einen Silikonkern zur Langzeitfreigabe von Androgenen - Google Patents

Implantat enthaltend einen Silikonkern zur Langzeitfreigabe von Androgenen

Info

Publication number
DE69902852T2
DE69902852T2 DE69902852T DE69902852T DE69902852T2 DE 69902852 T2 DE69902852 T2 DE 69902852T2 DE 69902852 T DE69902852 T DE 69902852T DE 69902852 T DE69902852 T DE 69902852T DE 69902852 T2 DE69902852 T2 DE 69902852T2
Authority
DE
Germany
Prior art keywords
androgens
long
term release
implant containing
silicone core
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69902852T
Other languages
English (en)
Other versions
DE69902852D1 (de
Inventor
Alfred J Moo-Young
Saleh I Saleh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Population Council Inc
Original Assignee
Population Council Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Population Council Inc filed Critical Population Council Inc
Publication of DE69902852D1 publication Critical patent/DE69902852D1/de
Application granted granted Critical
Publication of DE69902852T2 publication Critical patent/DE69902852T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69902852T 1998-07-02 1999-07-01 Implantat enthaltend einen Silikonkern zur Langzeitfreigabe von Androgenen Expired - Lifetime DE69902852T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/109,760 US6117441A (en) 1998-07-02 1998-07-02 Silicone core long term androgen delivery implant

Publications (2)

Publication Number Publication Date
DE69902852D1 DE69902852D1 (de) 2002-10-17
DE69902852T2 true DE69902852T2 (de) 2003-01-16

Family

ID=22329420

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69902852T Expired - Lifetime DE69902852T2 (de) 1998-07-02 1999-07-01 Implantat enthaltend einen Silikonkern zur Langzeitfreigabe von Androgenen

Country Status (12)

Country Link
US (1) US6117441A (de)
EP (1) EP0970704B1 (de)
JP (1) JP4713700B2 (de)
AR (1) AR019198A1 (de)
AT (1) ATE223733T1 (de)
BR (1) BR9902528A (de)
CA (1) CA2276587C (de)
DE (1) DE69902852T2 (de)
DK (1) DK0970704T3 (de)
ES (1) ES2186280T3 (de)
HU (1) HU223690B1 (de)
PT (1) PT970704E (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006506385A (ja) * 2002-10-22 2006-02-23 ザ バイオメリックス コーポレーション 治療剤を小嚢内デリバリーするための方法およびシステム
ES2660627T3 (es) 2003-05-15 2018-03-23 Biomerix Corporation Matrices elastoméricas reticuladas, su fabricación y su utilización en dispositivos implantables
US20050131325A1 (en) * 2003-12-16 2005-06-16 How-Lun Chen Flexible injection port
US20050131383A1 (en) * 2003-12-16 2005-06-16 How-Lun Chen Method for implanting flexible injection port
US7763077B2 (en) 2003-12-24 2010-07-27 Biomerix Corporation Repair of spinal annular defects and annulo-nucleoplasty regeneration
AU2005269988B2 (en) 2004-07-02 2012-02-02 Mati Therapeutics Inc. Treatment medium delivery device and methods for delivery
AU2005325213B2 (en) 2004-08-04 2010-10-07 Evonik Corporation Methods for manufacturing delivery devices and devices thereof
WO2006026844A1 (en) * 2004-09-09 2006-03-16 Biolab Sanus Farmacêutica Ltda. Hormone delayed release composition on the basis of polyorganosiloxanes or ethylene vinyl acetate resp. process for its manufacture
US20060093639A1 (en) * 2004-10-29 2006-05-04 Starkebaum Warren L Method and device for destroying body tissue
GB0504657D0 (en) * 2005-03-05 2005-04-13 Psimedica Ltd Compositions and methods of treatment
KR20110038144A (ko) 2006-03-31 2011-04-13 큐엘티 플러그 딜리버리, 인코포레이티드 비루관계에 대한 약물 전달 방법, 구조, 및 조성물
CA2698580C (en) 2007-09-07 2016-10-11 Qlt Plug Delivery, Inc. Lacrimal implant detection
KR101996336B1 (ko) * 2007-09-07 2019-07-04 마티 테라퓨틱스 인코포레이티드 치료 약제의 서방성 약물 코어
ES2718612T3 (es) 2007-12-20 2019-07-03 Evonik Corp Procedimiento para preparar micropartículas que tienen un bajo volumen de disolvente residual
LT2547332T (lt) * 2010-03-16 2018-12-10 Titan Pharmaceuticals, Inc. Heterogeninės implantuojamos priemonės, skirtos vaisto pristatymui
EP2476409A1 (de) 2011-01-14 2012-07-18 Université Catholique De Louvain Implantat mit einem Kern und einer den Kern umschliessenden Röhre
EP3597176A1 (de) 2014-08-19 2020-01-22 The Regents Of The University Of California Implantate zur lokalisierten wirkstofffreisetzung und verfahren zu deren verwendung
US11690807B2 (en) * 2018-05-24 2023-07-04 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
SG11202005949UA (en) 2018-05-24 2020-07-29 Celanese Eva Performance Polymers Corp Implantable device for sustained release of a macromolecular drug compound
US11338119B2 (en) 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11173291B2 (en) 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11344526B2 (en) 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3832252A (en) * 1970-09-29 1974-08-27 T Higuchi Method of making a drug-delivery device
US3710795A (en) * 1970-09-29 1973-01-16 Alza Corp Drug-delivery device with stretched, rate-controlling membrane
US4052505A (en) * 1975-05-30 1977-10-04 Alza Corporation Ocular therapeutic system manufactured from copolymer
US4191741A (en) * 1978-09-22 1980-03-04 Eli Lilly And Company Removable drug implant
US4234571A (en) * 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
US4451253A (en) * 1980-12-18 1984-05-29 Harman Sherman M Means and method for administering medicinals
JPH0761959B2 (ja) * 1985-10-11 1995-07-05 住友製薬株式会社 シリコンエラストマ−系徐放性製剤
US4666441A (en) * 1985-12-17 1987-05-19 Ciba-Geigy Corporation Multicompartmentalized transdermal patches
US5028430A (en) * 1987-05-08 1991-07-02 Syntex (U.S.A.) Inc. Delivery systems for the controlled administration of LHRH analogs
DE19975054I2 (de) * 1987-08-08 2000-04-13 Akzo Nobel Nv Kontrazeptives Implantat
US5035891A (en) * 1987-10-05 1991-07-30 Syntex (U.S.A.) Inc. Controlled release subcutaneous implant
GB8806367D0 (en) * 1988-03-17 1988-04-13 Erba Carlo Spa Siloxane matrices with internal non-uniform drug distribution
US4942037A (en) * 1988-06-02 1990-07-17 Merck & Co., Inc. Transdermal delivery systems
IN171596B (de) * 1989-06-27 1992-11-21 Cohen Michael
AU651654B2 (en) * 1992-01-14 1994-07-28 Endo Pharmaceuticals Solutions Inc. Manufacture of water-swellable hydrophilic articles and drug delivery devices
US5266325A (en) * 1990-09-28 1993-11-30 Hydro Med Science Division Of National Patent Development Corp. Preparation of homogeneous hydrogel copolymers
JPH05238929A (ja) * 1992-02-27 1993-09-17 Sumitomo Pharmaceut Co Ltd 代謝性骨疾患治療用長期持続性製剤
FR2695826B1 (fr) * 1992-09-21 1995-01-06 Theramex Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention.
US5660848A (en) * 1994-11-02 1997-08-26 The Population Council, Center For Biomedical Research Subdermally implantable device
US5733565A (en) * 1996-02-23 1998-03-31 The Population Council, Center For Biomedical Research Male contraceptive implant

Also Published As

Publication number Publication date
EP0970704B1 (de) 2002-09-11
PT970704E (pt) 2003-01-31
US6117441A (en) 2000-09-12
ATE223733T1 (de) 2002-09-15
HUP9902225A2 (hu) 2002-01-28
DE69902852D1 (de) 2002-10-17
DK0970704T3 (da) 2003-01-20
BR9902528A (pt) 2000-05-02
CA2276587A1 (en) 2000-01-02
JP4713700B2 (ja) 2011-06-29
HU9902225D0 (en) 1999-08-30
EP0970704A1 (de) 2000-01-12
CA2276587C (en) 2006-10-24
HU223690B1 (hu) 2004-12-28
JP2000044489A (ja) 2000-02-15
AR019198A1 (es) 2001-12-26
ES2186280T3 (es) 2003-05-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition