DE69831403D1 - Gerät zur isolation kleiner polymer-kugeln von einer suspension solcher kugeln - Google Patents

Gerät zur isolation kleiner polymer-kugeln von einer suspension solcher kugeln

Info

Publication number
DE69831403D1
DE69831403D1 DE69831403T DE69831403T DE69831403D1 DE 69831403 D1 DE69831403 D1 DE 69831403D1 DE 69831403 T DE69831403 T DE 69831403T DE 69831403 T DE69831403 T DE 69831403T DE 69831403 D1 DE69831403 D1 DE 69831403D1
Authority
DE
Germany
Prior art keywords
balls
suspension
beads
small polymer
bead
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69831403T
Other languages
English (en)
Other versions
DE69831403T2 (de
Inventor
Frank Paul
John James
C Payne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of DE69831403D1 publication Critical patent/DE69831403D1/de
Application granted granted Critical
Publication of DE69831403T2 publication Critical patent/DE69831403T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00457—Dispensing or evacuation of the solid phase support
    • B01J2219/00459—Beads
    • B01J2219/00468—Beads by manipulation of individual beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optical Measuring Cells (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Seal Device For Vehicle (AREA)
  • Glass Compositions (AREA)
DE69831403T 1997-04-08 1998-04-08 Gerät zur isolation kleiner polymer-kugeln von einer suspension solcher kugeln Expired - Fee Related DE69831403T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9707096.5A GB9707096D0 (en) 1997-04-08 1997-04-08 Novel device
GB9707096 1997-04-08
PCT/GB1998/001039 WO1998045683A1 (en) 1997-04-08 1998-04-08 Device for isolating small polymeric beads from a suspension of such beads

Publications (2)

Publication Number Publication Date
DE69831403D1 true DE69831403D1 (de) 2005-10-06
DE69831403T2 DE69831403T2 (de) 2006-06-01

Family

ID=10810448

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69831403T Expired - Fee Related DE69831403T2 (de) 1997-04-08 1998-04-08 Gerät zur isolation kleiner polymer-kugeln von einer suspension solcher kugeln

Country Status (9)

Country Link
US (1) US6332540B1 (de)
EP (1) EP0974046B1 (de)
JP (1) JP2001521439A (de)
AT (1) ATE303591T1 (de)
CA (1) CA2286213C (de)
DE (1) DE69831403T2 (de)
ES (1) ES2246068T3 (de)
GB (1) GB9707096D0 (de)
WO (1) WO1998045683A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1562035B1 (de) 1997-01-31 2017-01-25 Xy, Llc Optischer Apparat und optisches Verfahren
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6473171B1 (en) * 1999-01-15 2002-10-29 Coors Brewing Company Biocompatible apparatus for ultrasensitive and rapid detection of contaminants in liquids
US6151973A (en) * 1999-01-29 2000-11-28 Glaxo Wellcome Inc. Bead picking apparatus and method
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
US6263745B1 (en) * 1999-12-03 2001-07-24 Xy, Inc. Flow cytometer nozzle and flow cytometer sample handling methods
AU2002220018A1 (en) 2000-11-29 2002-06-11 Colorado State University System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US7252987B2 (en) * 2001-12-06 2007-08-07 Islet Technology, Inc. System for analysis and selection of encapsulated cellular materials
US7223371B2 (en) * 2002-03-14 2007-05-29 Micronics, Inc. Microfluidic channel network device
US20030175980A1 (en) * 2002-03-14 2003-09-18 Hayenga Jon W. Ribbon flow cytometry and cell sorting
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
CA2532376C (en) 2002-08-01 2015-05-12 Colorado State University Research Foundation Low pressure sperm cell separation system
US8436268B1 (en) * 2002-08-12 2013-05-07 Ecullet Method of and apparatus for type and color sorting of cullet
BRPI0313476B1 (pt) 2002-08-15 2015-06-23 Xy Llc Citômetro de fluxo de alta resolução
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
MX345105B (es) 2003-03-28 2017-01-16 Inguran Llc * Método de fotodaño para separar partículas.
AU2004242121B2 (en) 2003-05-15 2010-06-24 Xy, Llc. Efficient haploid cell sorting for flow cytometer systems
AU2005228893B2 (en) 2004-03-29 2010-08-19 Inguran, Llc Sperm suspensions for sorting into X or Y chromosome-bearing enriched populations
JP2008507287A (ja) 2004-07-22 2008-03-13 モンサント テクノロジー エルエルシー 精子細胞の集団を富化する方法
US8551763B2 (en) * 2007-10-12 2013-10-08 Fio Corporation Flow focusing method and system for forming concentrated volumes of microbeads, and microbeads formed further thereto
EP2356426B1 (de) * 2008-11-14 2020-04-15 Beckman Coulter, Inc. Monolithische optische flusszellen und herstellungsverfahren dafür
US20100230330A1 (en) * 2009-03-16 2010-09-16 Ecullet Method of and apparatus for the pre-processing of single stream recyclable material for sorting
JP5887275B2 (ja) * 2009-12-04 2016-03-16 ライフ テクノロジーズ コーポレーション アコースティックフローサイトメトリーのための装置、システム、方法、およびコンピュータ読み取り可能な媒体
US8871500B2 (en) * 2011-01-21 2014-10-28 Innovative Micro Technology MEMS particle sorting actuator and method of manufacturing
JP6036496B2 (ja) * 2012-07-24 2016-11-30 ソニー株式会社 微小粒子分取方法
WO2014047206A1 (en) * 2012-09-18 2014-03-27 Cytonome/St, Llc Flow cell for particle sorting
GB201509640D0 (en) * 2015-06-03 2015-07-15 Sphere Fluidics Ltd Systems and methods
EP3443323B1 (de) * 2016-04-15 2023-11-29 Becton, Dickinson and Company Tröpfchensortierer in einem gehäuse, verfahren zur verwendung davon, und kit
KR102135327B1 (ko) * 2018-07-26 2020-07-20 한국기계연구원 단일 입자 디스펜싱 장치 및 이를 이용한 단일 입자 디스펜싱 방법
US20230249224A1 (en) * 2021-04-04 2023-08-10 Micro Recycling Systems L.L.C. Apparatus and method for separating or sorting a set of parts

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826364A (en) * 1972-05-22 1974-07-30 Univ Leland Stanford Junior Particle sorting method and apparatus
US3827555A (en) * 1973-03-05 1974-08-06 Bio Physics Systems Inc Particle sorter with segregation indicator
US3984307A (en) * 1973-03-05 1976-10-05 Bio/Physics Systems, Inc. Combined particle sorter and segregation indicator
EP0177718B1 (de) * 1984-09-11 1989-12-06 Partec AG Verfahren und Vorrichtung zur Sortierung von mikroskopischen Partikeln
JPH0699490B2 (ja) * 1986-12-19 1994-12-07 鐘淵化学工業株式会社 懸濁重合方法及び懸濁重合装置
US5089126A (en) * 1989-03-31 1992-02-18 Lehigh University Method and apparatus for capillary hydrodynamic fractionation
GB9008044D0 (en) 1990-04-09 1990-06-06 Hatfield Polytechnic Higher Ed Microfabricated device for biological cell sorting
TW239881B (de) * 1992-12-22 1995-02-01 Sienna Biotech Inc
GB9310557D0 (en) * 1993-05-21 1993-07-07 Smithkline Beecham Plc Novel process and apparatus
US5726404A (en) 1996-05-31 1998-03-10 University Of Washington Valveless liquid microswitch

Also Published As

Publication number Publication date
CA2286213A1 (en) 1998-10-15
EP0974046B1 (de) 2005-08-31
GB9707096D0 (en) 1997-05-28
ATE303591T1 (de) 2005-09-15
EP0974046A1 (de) 2000-01-26
ES2246068T3 (es) 2006-02-01
CA2286213C (en) 2009-01-13
JP2001521439A (ja) 2001-11-06
WO1998045683A1 (en) 1998-10-15
DE69831403T2 (de) 2006-06-01
US6332540B1 (en) 2001-12-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee