DE69829182D1 - Modulare anordnung zur reagenzlosen affinitätsseparation und detektion von analyten - Google Patents

Modulare anordnung zur reagenzlosen affinitätsseparation und detektion von analyten

Info

Publication number
DE69829182D1
DE69829182D1 DE69829182T DE69829182T DE69829182D1 DE 69829182 D1 DE69829182 D1 DE 69829182D1 DE 69829182 T DE69829182 T DE 69829182T DE 69829182 T DE69829182 T DE 69829182T DE 69829182 D1 DE69829182 D1 DE 69829182D1
Authority
DE
Germany
Prior art keywords
analytes
reagent
detection
analyte
affinity separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69829182T
Other languages
English (en)
Other versions
DE69829182T2 (de
Inventor
P Lopez
A Sklar
Philip Hampton
Leonard Tender
Kimberly Opperman
Emmanuil Rabinovich
K Jain
Juchao Yan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of New Mexico UNM
Original Assignee
University of New Mexico UNM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of New Mexico UNM filed Critical University of New Mexico UNM
Application granted granted Critical
Publication of DE69829182D1 publication Critical patent/DE69829182D1/de
Publication of DE69829182T2 publication Critical patent/DE69829182T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Nanotechnology (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
DE69829182T 1997-04-11 1998-04-10 Modulare anordnung zur reagenzlosen affinitätsseparation und detektion von analyten Expired - Lifetime DE69829182T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4350197P 1997-04-11 1997-04-11
US43501P 1997-04-11
PCT/US1998/006871 WO1998047001A1 (en) 1997-04-11 1998-04-10 Modular assembly for reagentless affinity separation and detection of analyte

Publications (2)

Publication Number Publication Date
DE69829182D1 true DE69829182D1 (de) 2005-04-07
DE69829182T2 DE69829182T2 (de) 2005-12-29

Family

ID=21927477

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69829182T Expired - Lifetime DE69829182T2 (de) 1997-04-11 1998-04-10 Modulare anordnung zur reagenzlosen affinitätsseparation und detektion von analyten

Country Status (6)

Country Link
US (1) US6660532B1 (de)
EP (1) EP0988549B1 (de)
AT (1) ATE290211T1 (de)
CA (1) CA2285957A1 (de)
DE (1) DE69829182T2 (de)
WO (1) WO1998047001A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060160916A1 (en) * 2004-08-13 2006-07-20 Dyer Daniel J Process for modifying substrates with grafted polymers
US20070141597A1 (en) * 2005-10-25 2007-06-21 Harmon H J Biomimetic Biodetector of Toxins, Viruses, Bacteria, and Biological Factors
DE102005062003A1 (de) * 2005-12-22 2007-06-28 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Vorrichtung und Verfahren zur Detektion und/oder quantitativen Messung eines Zielmediums
WO2009148651A1 (en) * 2008-02-28 2009-12-10 Board Of Regents, The University Of Texas System Compositions and methods for detection of small molecules using dyes derivatized with analyte responsive receptors in a chemiluminescent assay
DE102014224449A1 (de) * 2014-11-28 2016-06-02 Forschungszentrum Jülich GmbH Szintillationsdetektor mit hoher Zählrate
WO2018136932A1 (en) * 2017-01-23 2018-07-26 Mendes Sergio Brito Electrically-modulated biosensors using electro-active waveguides

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310687A (en) 1984-10-31 1994-05-10 Igen, Inc. Luminescent metal chelate labels and means for detection
US4801726A (en) 1986-04-15 1989-01-31 Northeastern University Repetitive hit-and-run immunoassay and stable support-analyte conjugates; applied to T-2 toxin
US5135876A (en) * 1987-09-24 1992-08-04 University Of Utah Method and apparatus for the regulation of complex binding
US5229302A (en) * 1988-03-29 1993-07-20 Matsushita Electric Industrial Co., Ltd. Fluorescence immunoassay method utilizing pseudo-antigens combined with fluorescent quenchers
US5491097A (en) * 1989-06-15 1996-02-13 Biocircuits Corporation Analyte detection with multilayered bioelectronic conductivity sensors
US5156810A (en) * 1989-06-15 1992-10-20 Biocircuits Corporation Biosensors employing electrical, optical and mechanical signals
US5268305A (en) * 1989-06-15 1993-12-07 Biocircuits Corporation Multi-optical detection system
CA2024548C (en) * 1989-09-05 2002-05-28 David Issachar Analyte specific chemical sensor
AU6753390A (en) * 1989-10-02 1991-04-28 University Of Michigan, The Bioanalytical detection system
EP0476545B1 (de) * 1990-09-14 1997-05-07 Tosoh Corporation Verfahren und Kit für Immunoassay
US5776672A (en) * 1990-09-28 1998-07-07 Kabushiki Kaisha Toshiba Gene detection method
US5154890A (en) * 1990-11-07 1992-10-13 Hewlett-Packard Company Fiber optic potassium ion sensor
US5914241A (en) * 1993-01-19 1999-06-22 Biosite Diagnostics, Inc. Assays and kits for detecting analytes in the presence of cross-reacting substances
IL108726A (en) * 1994-02-22 1999-12-31 Yissum Res Dev Co Electrobiochemical method and system for the determination of an analyte which is a member of a recognition pair in a liquid medium and electrodes therefor
US5624537A (en) 1994-09-20 1997-04-29 The University Of British Columbia - University-Industry Liaison Office Biosensor and interface membrane
EP0880544A4 (de) 1995-03-08 2003-01-15 Mat Adsorption Technologies Gm Oberflächenmodifizierte affinitätstrennmembran

Also Published As

Publication number Publication date
EP0988549A4 (de) 2002-09-04
US6660532B1 (en) 2003-12-09
DE69829182T2 (de) 2005-12-29
ATE290211T1 (de) 2005-03-15
CA2285957A1 (en) 1998-10-22
WO1998047001A1 (en) 1998-10-22
EP0988549B1 (de) 2005-03-02
EP0988549A1 (de) 2000-03-29

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