DE69734321D1 - Non-peptidische vasopressin via antagonisten - Google Patents
Non-peptidische vasopressin via antagonistenInfo
- Publication number
- DE69734321D1 DE69734321D1 DE69734321T DE69734321T DE69734321D1 DE 69734321 D1 DE69734321 D1 DE 69734321D1 DE 69734321 T DE69734321 T DE 69734321T DE 69734321 T DE69734321 T DE 69734321T DE 69734321 D1 DE69734321 D1 DE 69734321D1
- Authority
- DE
- Germany
- Prior art keywords
- vasopressin via
- via antagonists
- peptidic vasopressin
- peptidic
- antagonists
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1214996P | 1996-02-23 | 1996-02-23 | |
US1218896P | 1996-02-23 | 1996-02-23 | |
US1221596P | 1996-02-23 | 1996-02-23 | |
US12215P | 1996-02-23 | ||
US12149P | 1996-02-23 | ||
US12188P | 1996-02-23 | ||
GBGB9605044.8A GB9605044D0 (en) | 1996-03-09 | 1996-03-09 | Method and non-peptidyl agents for modulation of the vasopressin v1a receptor |
GB9605046 | 1996-03-09 | ||
GB9605045 | 1996-03-09 | ||
GBGB9605045.5A GB9605045D0 (en) | 1996-03-09 | 1996-03-09 | Method and non-peptidyl agents for modulation of the oxytocin receptor |
GB9605044 | 1996-03-09 | ||
GBGB9605046.3A GB9605046D0 (en) | 1996-03-09 | 1996-03-09 | Method for antagonism of the tachykinin receptor with non-peptide agents |
PCT/US1997/003039 WO1997030707A1 (en) | 1996-02-23 | 1997-02-20 | NON-PEPTIDYL VASOPRESSIN V1a ANTAGONISTS |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69734321D1 true DE69734321D1 (de) | 2006-02-16 |
DE69734321T2 DE69734321T2 (de) | 2006-08-10 |
Family
ID=27547258
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69734321T Expired - Lifetime DE69734321T2 (de) | 1996-02-23 | 1997-02-20 | Non-peptidische vasopressin via antagonisten |
Country Status (10)
Country | Link |
---|---|
US (3) | US6204260B1 (de) |
EP (1) | EP0939632B1 (de) |
JP (1) | JP4212112B2 (de) |
AT (1) | ATE305781T1 (de) |
AU (1) | AU1977997A (de) |
CA (1) | CA2246753C (de) |
DE (1) | DE69734321T2 (de) |
DK (1) | DK0939632T3 (de) |
ES (1) | ES2248840T3 (de) |
WO (1) | WO1997030707A1 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2746824A1 (en) | 1999-08-16 | 2001-01-22 | Revaax Pharmaceuticals, Llc | Neurotherapeutic composition and method |
US6489319B2 (en) * | 1999-08-16 | 2002-12-03 | Revaax Pharmaceuticals, Llc | Neurotherapeutic use of carboxypeptidase inhibitors |
US6426342B2 (en) * | 1999-08-16 | 2002-07-30 | Revaax Pharmaceuticals, Llc | Use of β-lactamase inhibitors as neuroprotectants |
CA2389439A1 (en) | 1999-11-04 | 2001-05-10 | Ortho-Mcneil Pharmaceutical, Inc. | Nonpeptide substituted benzothiazepines as vasopressin antagonists |
ATE360014T1 (de) | 2001-06-15 | 2007-05-15 | Vicuron Pharm Inc | Bicyclische pyrrolidinverbindungen |
AR036053A1 (es) | 2001-06-15 | 2004-08-04 | Versicor Inc | Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas |
ES2666188T3 (es) * | 2001-10-12 | 2018-05-03 | Azevan Pharmaceuticals, Inc. | Antagonistas del v1a de vasopresina beta-lactámicos |
AU2002359761A1 (en) * | 2001-12-18 | 2003-06-30 | Invenux, Inc. | Antibiotic compounds |
US7208493B2 (en) * | 2002-10-03 | 2007-04-24 | Targegen, Inc. | Vasculostatic agents and methods of use thereof |
US20050282814A1 (en) * | 2002-10-03 | 2005-12-22 | Targegen, Inc. | Vasculostatic agents and methods of use thereof |
WO2005035492A1 (en) * | 2003-10-03 | 2005-04-21 | Serenix Pharmaceuticals, Llc. | 3-SUBSTITUTED β-LACTAMYL VASOPRESSIN V1A ANTAGONISTS |
CA2567574C (en) * | 2004-04-08 | 2013-01-08 | Targegen, Inc. | Benzotriazine inhibitors of kinases |
NZ553492A (en) | 2004-08-25 | 2010-11-26 | Targegen Inc | Triazole derivatives and methods of use |
AU2006227199A1 (en) * | 2005-03-22 | 2006-09-28 | Azevan Pharmaceuticals, Inc. | Beta-lactamylalkanoic acids for treating premenstrual disorders |
AU2013206201B2 (en) * | 2005-03-22 | 2016-06-16 | Azevan Pharmaceuticals, Inc. | Beta-lactamylalkanoic acids for treating premenstrual disorders |
EP1893216A4 (de) * | 2005-06-08 | 2012-08-08 | Targegen Inc | Verfahren und zusammensetzungen zur behandlung von augenerkrankungen |
US8048874B2 (en) * | 2005-07-19 | 2011-11-01 | Azevan Pharmaceuticals, Inc. | Beta-lactamyl phenylalanine, cysteine, and serine vasopressin antagonists |
US8133900B2 (en) * | 2005-11-01 | 2012-03-13 | Targegen, Inc. | Use of bi-aryl meta-pyrimidine inhibitors of kinases |
PT1951684T (pt) * | 2005-11-01 | 2016-10-13 | Targegen Inc | Inibidores de cinases de tipo biaril-meta-pirimidina |
US8604042B2 (en) * | 2005-11-01 | 2013-12-10 | Targegen, Inc. | Bi-aryl meta-pyrimidine inhibitors of kinases |
US7691858B2 (en) * | 2006-04-25 | 2010-04-06 | Targegen, Inc. | Kinase inhibitors and methods of use thereof |
US20100016274A1 (en) * | 2006-09-14 | 2010-01-21 | Koppel Gary A | Beta-lactam cannabinoid receptor modulators |
WO2010127125A1 (en) * | 2009-04-29 | 2010-11-04 | Rexahn Pharmaceuticals, Inc. | Clavulanate formulation for neuroprotection and treatment of neurodegenerative disorders |
RU2623209C9 (ru) | 2010-07-01 | 2018-01-22 | Азеван Фармасьютикалз, Инк. | Способы лечения посттравматического стрессового расстройства |
AU2010363329A1 (en) | 2010-11-07 | 2013-05-09 | Targegen, Inc. | Compositions and methods for treating myelofibrosis |
DK3122743T3 (da) | 2014-03-28 | 2023-02-20 | Azevan Pharmaceuticals Inc | Sammensætninger og fremgangsmåder til behandling af neurodegenerative sygdomme |
CN111295373A (zh) | 2017-09-15 | 2020-06-16 | 阿泽凡药物公司 | 用于治疗脑损伤的组合物和方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4751299A (en) | 1983-11-18 | 1988-06-14 | Takeda Chemical Industries, Ltd. | Optically active β-lactams and method of their production |
US4665171A (en) | 1985-07-17 | 1987-05-12 | Harvard University | Process and intermediates for β-lactam antibiotics |
US4673737A (en) | 1985-08-02 | 1987-06-16 | Harvard University | 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof |
EP0215435B1 (de) | 1985-09-09 | 1993-03-03 | Otsuka Pharmaceutical Co., Ltd. | 2-Oxa-isocephemverbindungen, sie enthaltende Zusammensetzungen und Verfahren zu deren Herstellung |
US4734498A (en) | 1986-07-10 | 1988-03-29 | Eli Lilly And Company | 3β-succinimidoazetidinones as chiral intermediates |
US4772694A (en) | 1986-07-24 | 1988-09-20 | Eli Lilly And Company | Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates |
DK123488A (da) | 1987-03-09 | 1988-09-10 | Otsuka Pharma Co Ltd | 2-oxa-isocephemforbindelser, praeparater indeholdende dem, og fremgangsmaader til fremstilling af dem |
US5373089A (en) | 1988-09-02 | 1994-12-13 | Northwestern University | Oxytocin antagonist |
US5068232A (en) * | 1990-04-10 | 1991-11-26 | American Cyanamid Company | Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them |
US5521307A (en) * | 1992-02-18 | 1996-05-28 | Eli Lilly And Company | Methods and compounds for the preparation of carbacephems |
WO1994010143A1 (en) * | 1992-10-27 | 1994-05-11 | Merck & Co., Inc. | New substituted azetidinones as anti-inflammatory and antidegenerative agents |
US5631365A (en) * | 1993-09-21 | 1997-05-20 | Schering Corporation | Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents |
AU4368896A (en) * | 1994-11-23 | 1996-06-17 | Affymax Technologies N.V. | Methods for synthesizing diverse collections of beta-lactam compounds |
WO1996032408A1 (en) * | 1995-03-31 | 1996-10-17 | Synphar Laboratories, Inc. | Novel 4-substituted-3-peptidyl-azetidin-2-one derivatives useful as cysteine proteinase inhibitor |
AU5487496A (en) * | 1995-05-03 | 1996-11-21 | Eli Lilly And Company | Combinatorial process for synthesizing azetidinone analogs |
-
1997
- 1997-02-20 DK DK97907895T patent/DK0939632T3/da active
- 1997-02-20 JP JP52964797A patent/JP4212112B2/ja not_active Expired - Lifetime
- 1997-02-20 EP EP97907895A patent/EP0939632B1/de not_active Expired - Lifetime
- 1997-02-20 CA CA002246753A patent/CA2246753C/en not_active Expired - Lifetime
- 1997-02-20 AT AT97907895T patent/ATE305781T1/de active
- 1997-02-20 WO PCT/US1997/003039 patent/WO1997030707A1/en active IP Right Grant
- 1997-02-20 ES ES97907895T patent/ES2248840T3/es not_active Expired - Lifetime
- 1997-02-20 AU AU19779/97A patent/AU1977997A/en not_active Abandoned
- 1997-02-20 DE DE69734321T patent/DE69734321T2/de not_active Expired - Lifetime
- 1997-02-20 US US09/125,737 patent/US6204260B1/en not_active Expired - Lifetime
-
2000
- 2000-12-08 US US09/733,430 patent/US6521611B2/en not_active Expired - Lifetime
-
2002
- 2002-12-20 US US10/327,240 patent/US6610680B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE305781T1 (de) | 2005-10-15 |
EP0939632A1 (de) | 1999-09-08 |
CA2246753A1 (en) | 1997-08-28 |
JP4212112B2 (ja) | 2009-01-21 |
DK0939632T3 (da) | 2006-01-30 |
EP0939632B1 (de) | 2005-10-05 |
CA2246753C (en) | 2005-05-10 |
WO1997030707A1 (en) | 1997-08-28 |
DE69734321T2 (de) | 2006-08-10 |
JP2000504731A (ja) | 2000-04-18 |
ES2248840T3 (es) | 2006-03-16 |
EP0939632A4 (de) | 2002-09-25 |
US20020049187A1 (en) | 2002-04-25 |
AU1977997A (en) | 1997-09-10 |
US6521611B2 (en) | 2003-02-18 |
US6204260B1 (en) | 2001-03-20 |
US6610680B1 (en) | 2003-08-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69734321D1 (de) | Non-peptidische vasopressin via antagonisten | |
AU3998693A (en) | Angiotensin ii antagonists | |
ATE219077T1 (de) | Endothelin antagoniste | |
MX9703186A (es) | Antagonistas del receptor del neuropeptido y de indolilo. | |
TR199802269T2 (xx) | Endotelin resept�r antagonistleri olarak faydal� indol t�revleri. | |
AU2956095A (en) | Heterocyclic tachykinin receptor antagonists | |
TR199801255T2 (xx) | Vitronektin resept�r antagonistleri. | |
DE69935873D1 (de) | 2-Methyl-thieno-benzodiazepin Formulierung | |
TR199801268T2 (xx) | Ta�ikinin antagonistleri olarak 3-Azetidinilalkilpiperidinler veya pirolidinler. | |
DE69703242D1 (de) | Indolin-derivate verwendbar als 5-ht-2c rezeptor-antagonisten | |
DE60028928D1 (de) | Verwendung von angiotensin ii rezeptorantagonisten zur behandlung von akutem myokardischen infarkt | |
AU3476599A (en) | Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression (5-ht1 receptor antagonists) | |
ATE208764T1 (de) | Isazole derivate als fibrinogen-rezeptor- antagonisten | |
DE69526738D1 (de) | Endothelin-rezeptor-antagonisten | |
DK0900218T3 (da) | Heterocykliske forbindelser | |
EA199800204A1 (ru) | Антагонисты 5-нтрецепторов для лечения дискинезии |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |